Hephaestin antibody

Principal name

Hephaestin antibody

Alternative names for Hephaestin antibody

HEPH, KIAA0698

SwissProt ID

Q920H8 (Rat), Q9BQS7 (Human), Q9Z0Z4 (Mouse)

Gene ID

9843 (HEPH), 117240 (Heph)

Available reactivities

Hu (Human), Rt (Rat), Ms (Mouse), Can (Canine), Por (Porcine), Ze (Zebrafish), Bov (Bovine), Eq (Equine), GP (Guinea Pig), Rb (Rabbit), Sh (Sheep)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of Hephaestin antibody

Hephaestin is a single-pass type I membrane protein that belongs to the multicopper oxidase family of proteins. Hephaestin, a copper-dependant ferroxidase protein, is crucial for iron exiting intestinal enterocytes into the circulation. It mediates the movement of iron across the basolateral membrane in conjunction with ferroportin 1. This is an important link between iron and copper metabolism in mammalian systems, as copper deficiency leads to reduced hephaestin and reduced iron absorption resulting in anemia. Hephaestin can bind six copper ions per monomer and is regulated by the homeobox transcription factor CDX2. Increased levels of iron leads to an increase in CDX2 expression and thus Hephaestin. Hephaestin is primarily detected in the intestine, but is also expressed in colon, breast, bone trabecural cells and fibroblasts.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Hephaestin antibody

WB Suggested Anti-HEPH Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: MCF7 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Sh, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

Hephaestin antibody

Hephaestin Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

Hephaestin antibody

HEPH monoclonal antibody (M01), clone 2D3 Western Blot analysis of HEPH expression in K-562 ( Cat # L009V1 ). Mouse IgG2a 2D3 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Hephaestin antibody

Hephaestin Rabbit Rt E, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

Hephaestin antibody

Human MCF-7; WB Suggested Anti-HEPH Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: MCF7 cell lysate; HEPH antibody - N-terminal region (ARP47078_P050) in Human MCF-7 cells using Western Blot Rabbit Aff - Purified Can, Hu, Ms, Por, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

Hephaestin antibody

Immunohistochemistry-Paraffin: Hephaestin Antibody [NBP1-85483] - Immunohistochemical staining of human colon shows moderate cytoplasmic and membranous positivity in glandular cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Hephaestin (transcript variant 2)

Hephaestin Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Hephaestin (transcript variant 1)

Hephaestin Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Hephaestin

Hephaestin Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

Hephaestin

Hephaestin Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

HEPH overexpression lysate

HEPH overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

HEPH overexpression lysate

HEPH overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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