Alternative names for HERC1 antibody
p532, p619, Probable E3 ubiquitin-protein ligase HERC1, HECT domain and RCC1-like domain-containing protein 1
Immunoprecipitation (IP), Western blot / Immunoblot (WB), Paraffin Sections (P)
Background of HERC1 antibody
HERC1 (HECT domain and RCC1-like domain-containing protein 1) belongs to the HERC family of ubiquitin ligases. It is involved in membrane traffic via its ability to bind clathrin and its guanine nucleotide exchange factor (GEF) activity for Arf and Rab. HERC1 has been found to interact with TSC2 (tuberous sclerosis complex 2) and may be involved with its destabilization. Alternative names for HERC1 include p532 and p619.