Herpes Virus Type 8 / HHV8 antibody

Principal name

Herpes Virus Type 8 / HHV8 antibody

Alternative names for Herpes Virus Type 8 / HHV8 antibody

HHV-8, KHSV

Gene ID

4961461

Available reactivities

Hu (Human), Vi (Virus)

Available hosts

Rat, Mouse, Rabbit, Sheep

Available applications

Paraffin Sections (P), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Frozen Sections (C), Immunoprecipitation (IP)

Background of Herpes Virus Type 8 / HHV8 antibody

ORF57 (also known as MTA), one of the earliest Kaposi's sarcoma-associated herpesvirus (KSHV) regulatory proteins to be expressed, is essential for virus lytic replication. A counterpart is present in every herpesvirus sequenced, indicating the importance of this signature viral protein, and those examined act post-transcriptionally, affecting RNA splicing and transport. KSHV ORF57 is capable of establishing both lytic and latent replication cycles. In KS, the virus localizes to tumor progenitor endothelial cells, most of which are latently infected. In cell culture, KSHV replication is generally studied using B-cell lines, such as BCBL-1, generated from primary effusion lymphoma material. Most BCBL-1 cells are latently infected, although there is some spontaneous virus reactivation. Addition of chemical inducers such as sodium n-butyrate, 12-O-tetradecanoylphorbol-13-acetate (TPA), and valproic acid (VA) to these cells efficiently induces the lytic cycle and produces virions. KSHV ORF57 protein predominantly localizes to the nucleus and can shuttle between the nucleus and cytoplasm. Most HSV-1 genes are unspliced; by contrast, ORF57 is spliced gene; the protein is 455 amino acids in length and 50kDa in size.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Herpes Virus Type 8 / HHV8 ORF62 antibody

Herpes Virus Type 8 / HHV8 Sheep IgG Purified WB
0.25 mg / €360.00
  Acris Antibodies GmbH

Herpes Virus Type 8 / HHV8 Cyclin antibody

Herpes Virus Type 8 / HHV8 Sheep IgG Purified Hu IP, WB
0.25 mg / €360.00
  Acris Antibodies GmbH

Herpes Virus Type 8 / HHV8 (K8 alpha) antibody

Immunohistochemistry-Paraffin: KSHV K8 Antibody (8C12G10G1) [NB100-2189] - Immunohistochemical analysis of paraffin-embedded lung cancer tumor (left), mammary cancer tissues (right) using c-Jun Rabbit pAb with DAB staining. Mouse IgG2a 8C12G10G1 Ascites Vi E, ICC/IF, P, WB
0.1 ml / €440.00
  Novus Biologicals Inc.

Herpes Virus Type 8 / HHV8 Minor Capsid Protein antibody

Herpes Virus Type 8 / HHV8 Sheep IgG Purified Hu IP, WB
0.25 mg / €360.00
  Acris Antibodies GmbH

Herpes Virus Type 8 / HHV8 ORF57 antibody

Western blot using affinity purified anti-KSHV FORF57 to detect KSHV ORF57 in HEK293 cells transfected with ORF57 expression vector and ORF57 truncations, or in KSHV infected B-cell line (BCBL-1) treated with or without valproic acid to induce viral replication (arrow). The membrane was probed with the primary antibody diluted 1:7,500 (left) and 1:1,000 (right). Rabbit IgG Aff - Purified Hu E, WB
0.1 mg / €440.00
  Acris Antibodies GmbH

Herpes Virus Type 8 / HHV8 ORF57 antibody

Western blot using affinity purified anti-KSHV FORF57 to detect KSHV ORF57 in HEK293 cells transfected with ORF57 expression vector and ORF57 truncations, or in KSHV infected B-cell line (BCBL-1) treated with or without valproic acid to induce viral replication (arrow). The membrane was probed with the primary antibody diluted 1:7,500 (left) and 1:1,000 (right). Rabbit IgG Aff - Purified Hu E, WB
25 µl / €190.00
  Acris Antibodies GmbH

Herpes Virus Type 8 / HHV8 antibody

Cultured cells infected with HHV8 stained with HHV8 antibody DM395 /DM395-05 (Clone LN53). Rat IgG2c LN53 Purified Hu P
1 ml / €520.00
  Acris Antibodies GmbH

Herpes Virus Type 8 / HHV8 antibody

Cultured cells infected with HHV8 stained with HHV8 antibody DM395 /DM395-05 (Clone LN53). Rat IgG2c LN53 Purified Hu P
0.5 ml / €340.00
  Acris Antibodies GmbH

Herpes Virus Type 8 / HHV8 ORF73 antibody

Transfected and non-transfected 293T cell lysates were resolved by SDS-PAGE, transferred to NC membrane and probed with ORF73/HHV8 monoclonal antibody, clone AT4C11 ( Cat # MAB4201 ; 1 : 1,000 ). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Mouse IgG2a AT4C11 E, WB
0.1 ml / €390.00
  Abnova Taiwan Corp.

Herpes Virus Type 8 / HHV8 (K8 alpha) antibody

Western blot analysis using KSHV K8a monoclonal antibody, clone 8C12G10G1 ( Cat # MAB5592 ) against TPA-induced BCBL-1 cell lysate. Mouse IgG2a 8C12G10G1 ICC/IF, WB
0.1 mg / €470.00
  Abnova Taiwan Corp.

Herpes Virus Type 8 / HHV8 gp59 antibody

Western blot using HHV8gp59 polyclonal antibody ( Cat # PAB10254 ) to detect HHV8gp59 in HEK293 cells transfected with HHV8gp59 expression vector and HHV8gp59 truncations, or in HHV8gp59 infected B-cell line ( BCBL-1 ) treated with or without valproic acid to induce viral replication ( arrow ).
The membrane was probed with the primary antibody diluted 1 : 7,500 ( left ) and 1:1,000 ( right ).
Personal Communication, V. Majerciak, M.Zheng, CCR-NC , Bethesda, MD. Rabbit Hu C, E, WB
0.1 mg / €560.00
  Abnova Taiwan Corp.

Herpes Virus Type 8 / HHV8 gp67 antibody

Herpes Virus Type 8 / HHV8 Sheep IgG Hu WB
0.25 mg / €400.00
  Abnova Taiwan Corp.

Herpes Virus Type 8 / HHV8 ORF8 antibody

Western blot analysis using KSHV ORF8 polyclonal antibody ( Cat # PAB14292 ) to KSHV ORF8 against uninduced BCBL-1 ( Lane 1 ); TPA-induced BCBL-1 ( Lane 2 ) and purified virion ( Lane 3 ). Rabbit IgG1 Hu WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

Herpes Virus Type 8 / HHV8 ORF8 antibody

Western Blot: KSHV ORF8 Antibody [NB100-2197] - Western blot analysis using anti-KSHV ORF8 polyclonal antiobdy against uninduced BCBL1 cell lysate (1), TPA induced BCBL1 cell lysate(2) and purified virion (3). Rabbit Serum Hu WB
0.1 mg / €380.00
  Novus Biologicals Inc.

Herpes Virus Type 8 / HHV8 gp78 antibody

Immunohistochemistry: HHV8gp78 Antibody (LN53) [NBP1-22767]-Cultured cells infected with HHV8 stained with HHV8 antibody Mouse IgG2c LN53 Supernatant Hu E
0.5 ml / €400.00
  Novus Biologicals Inc.

Herpes Virus Type 8 / HHV8 gp78 antibody

Herpes Virus Type 8 / HHV8 Mouse IgG2a AT4C11 Hu E, P, WB
0.1 ml / €380.00
  Novus Biologicals Inc.

16 Item(s)

per page
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