HES1 antibody

Principal name

HES1 antibody

Alternative names for HES1 antibody

HES-1, HL, HRY, Hairy-like, HHL, Hairy homolog, Hairy and enhancer of split 1

SwissProt ID

O57337 (Chick), P35428 (Mouse), Q04666 (Rat), Q14469 (Human), Q3ZBG4 (Bovin)

Gene ID

3280 (HES1), 29577 (Hes1), 15205

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Chk (Chicken), Por (Porcine), Ze (Zebrafish), African clawed frog, Mky (Monkey), Prim (Primate)

Available hosts

Rabbit, Goat, Mouse

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Dot blot (Dot), Flow Cytometry (F), Frozen Sections (C), Luminex (LMNX)

Background of HES1 antibody

HES1 is a nuclear protein belonging to th basic helix-loop-helix family of transcription factors with a basic helix-loop-helix (bHLH) domain and an Orange domain. The basic domain of HES1 contains a helix interrupting protein that binds to the N-box rather than the canonical E-box. An immediate early response gene to growth factor, HES1 is reported as having a dual function of both transcriptional activator and silencer of acid alpha-glucosidase (GAA), thus contributing to the subtle tissue-specific control of housekeeping genes such as GAA. HES1 a transcriptional repressor of genes which require a bHLH protein for their transcription and also the formation of a complex with a corepressor protein (Groucho) such as TLE2. HES1 may act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1.

General readings

Hoebeke,I., et al., (2006) Blood 107 (7), 2879-2881

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

HES1 antibody

Immunohistochemical staining of paraffin-embedded liver within the normal limits using anti-HES1 (TA500114) mouse monoclonal antibody (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min). Mouse IgG1 OTI4H1 Purified Hu ICC/IF, P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

HES1 antibody

Immunohistochemical staining of paraffin-embedded Human thyroid tissue within the normal limits using anti-HES1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504001) Mouse IgG1 OTI2D2 Purified Hu F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

HES1 antibody

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-HES1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504046) Mouse IgG2b OTI1B5 Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

HES1 antibody

HES1 ELISA with 1B5 Capture (TA600482) and 4H1 Detection (TA700482) Antibodies. Substrate used: Recombinant Human HES1 (TP311709) Mouse IgG1 OTI1B5 Purified Hu E, LMNX
0.1 mg / €325.00
  OriGene Technologies, Inc.

HES1 antibody

HES1 ELISA with 7B9 Capture (TA600484) and 2D2 Detection (TA700483) Antibodies. Substrate used: Recombinant Human HES1 (TP311709) Mouse IgG1 OTI7B9 Purified Hu E, LMNX
0.1 mg / €325.00
  OriGene Technologies, Inc.

HES1 antibody

HES1 Mouse IgG1 OTI2D2 Purified Hu E, LMNX
50 µg / €345.00
  OriGene Technologies, Inc.

HES1 antibody

HES1 ELISA with 2D2 Capture (TA600483) and 1B5 Detection (TA700484) Antibodies. Substrate used: Recombinant Human HES1 (TP311709) Mouse IgG1 OTI1B5 Purified Hu E, LMNX
50 µg / €345.00
  OriGene Technologies, Inc.

HES1 antibody

Human Heart; . Rabbit Anti-HES1 Antibody. . Catalog Number:. ARP32372 . Paraffin Embedded Tissue: Human cardiac cell . Cellular Data: Epithelial cells of renal tubule. Antibody Concentration: 4.0-8.0 ug/ml. Magnification: 400X Rabbit Aff - Purified African clawed frog, Bov, Chk, Hu, Ms, Por, Rt, Ze P, WB
0.1 mg / €310.00
  AVIVA Systems Biology

HES1 antibody

Immunohistochemistry-Paraffin: Hes1 Antibody (4H1) [NBP1-47791] - Immunohistochemical staining of paraffin-embedded Carcinoma of liver using anti-HES1 mouse monoclonal antibody. Mouse IgG1 4H1 Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €620.00
  Novus Biologicals Inc.

HES1 antibody

Immunohistochemistry-Paraffin: Hes1 Antibody [TA336954] - Analysis of HES1 in formalin-fixed paraffin-embedded human brain tissue using an isotype control (top left) and this antibody (bottom left, right) at 1:2000. Rabbit Purified Bov, Hu, Ms, Prim, Rt P
0.1 ml / €325.00
  OriGene Technologies, Inc.

HES1 antibody

HEK293T cells were transfected with pCMV6-ENTRY control (PS01, left panel) or HES1 cDNA (right panel) and incubated for 48 hours after transfection. The cells were detached, fixed with 2% formaldehyde for 30 min, permeabilized with 0.1% trixon-X100, and then stained with PE-labeled HES1 antibodies (TA400011). Mouse OTI4H1 Purified Hu F
0.1 ml / €325.00
  OriGene Technologies, Inc.

HES1 antibody

HEK293T cells were transfected with pCMV6-ENTRY control (Lane 1) or pCMV6-ENTRY HES1 (Lane 2) plasmids for 48 hrs. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-HES1-biotin and Streptavidin-HRP. Mouse OTI4H1 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

HES1 antibody

HEK293T cells were transfected with pCMV6-ENTRY control (Lane 1) or pCMV6-ENTRY HES1 (Lane 2) plasmids for 48 hrs. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-HES1-HRP. Mouse OTI4H1 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

HES1 antibody

Anti-HES1 mouse monoclonal antibody (TA503958) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY HES1(RC211709). Mouse IgG1 OTI1H8 Purified Hu F, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

HES1 antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of Human bladder tissue using anti-HES1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504002) Mouse IgG1 OTI1F11 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

HES1 antibody

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-HES1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504045) Mouse IgG1 OTI7B9 Purified Hu, Mky, Ms, Rt P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

HES1 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY HES1 (RC211709, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-HES1. Mouse IgG1 OTI1B9 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

HES1 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY HES1 (RC211709, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-HES1. Mouse IgG1 OTI2H4 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

HES1 antibody

HES1 ELISA with 2D2 Capture (TA600483) and 1B5 Detection (TA700484) Antibodies. Substrate used: Recombinant Human HES1 (TP311709) Mouse IgG1 OTI2D2 Purified Hu E, LMNX
0.1 mg / €325.00
  OriGene Technologies, Inc.

HES1 antibody

HES1 ELISA with 1F11 Capture (TA600485) and 1B5 Detection (TA700484) Antibodies. Substrate used: Recombinant Human HES1 (TP311709) Mouse IgG1 OTI1F11 Purified Hu E, LMNX
0.1 mg / €325.00
  OriGene Technologies, Inc.

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