Hexosaminidase D antibody

Principal name

Hexosaminidase D antibody

Alternative names for Hexosaminidase D antibody

HEXDC, Beta-hexosaminidase D, Hexosaminidase domain-containing protein, Beta-N-acetylhexosaminidase, N-acetyl-beta-galactosaminidase

SwissProt ID

A6QNR0 (Bovin), Q3U4H6 (Mouse), Q8WVB3 (Human)

Gene ID

284004 (HEXDC)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of Hexosaminidase D antibody

HEXDC, also known as hexosaminidase D, beta-hexosaminidase D, N-acetyl-beta-galactosaminidase, hexosaminidase domain-containing protein or beta-N-acetylhexosaminidase, is a 486 amino acid cytoplasmic and nuclear protein that has hexosaminidase activity and belongs to the glycosyl hydrolase 20 family. Existing as two alternatively spliced isoforms, HEXDC catalyzes the hydrolysis of non-reducing N-acetyl-D-hexosamine residues near the termini of N-acetyl-beta-D-hexosaminides. The gene encoding HEXDC maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Defects in p53 is associated with malignant cell growth and Li-Fraumeni syndrome. BRCA1 is directly involved in DNA repair and is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Hexosaminidase D antibody

WB Suggested Anti-HEXDC Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:12500; Positive Control: SH-SYSY cell lysate Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

Hexosaminidase D antibody

Western Blot analysis of HEXDC expression in transfected 293T cell line (H00284004-T01) by HEXDC MaxPab polyclonal antibody.

Lane 1: HEXDC transfected lysate(54.23 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

Hexosaminidase D antibody

Human SH-SYSY; WB Suggested Anti-HEXDC Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:12500. Positive Control: SH-SYSY cell lysate; HEXDC antibody - middle region (ARP55666_P050) in Human SH-SYSY cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

Hexosaminidase D antibody

Immunohistochemistry-Paraffin: HEXDC Antibody [NBP1-83573] - Immunohistochemical staining of human rectum shows strong cytoplasmic and nuclear positivity in glandular cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Hexosaminidase D antibody

Immunohistochemistry-Paraffin: HEXDC Antibody [NBP1-83574] - Immunohistochemical staining of human cerebellum shows strong cytoplasmic positivity in granular layer cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Hexosaminidase D antibody

Immunohistochemistry-Paraffin: HEXDC Antibody [NBP1-83575] - Immunohistochemical staining of human urinary bladder shows strong cytoplasmic and membranous positivity in superficial urothelial cells. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Hexosaminidase D

Hexosaminidase D Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

Hexosaminidase D

Hexosaminidase D Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

HEXDC 293T Cell Transient Overexpression Lysate(Denatured)

HEXDC 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

Lysates (Overexpressed)

Catalog No.    

HEXDC overexpression lysate

HEXDC overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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