HFE2 / Hemojuvelin antibody

Principal name

HFE2 / Hemojuvelin antibody

Alternative names for HFE2 / Hemojuvelin antibody

HJV, RGMC, Hemochromatosis type 2 protein, RGM domain family member C

SwissProt ID

Q6ZVN8 (Human), Q7TQ32 (Mouse), Q8N7M5 (Rat)

Gene ID

148738 (HFE2), 69585 (Hfe2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Flow Cytometry (F)

Background of HFE2 / Hemojuvelin antibody

Hemojuvelin (HJV/RGMc/HFE2) is a membrane-bound and soluble protein in mammals. It is a member of a three gene family (in vertebrates) called the repulsive guidance molecules. In mouse, the Hemojuvelin protein is encoded by the HFE2 gene, and it is mapped to Chromosome 3. It was concluded that downregulation of hepatic Hemojuvelin during inflammation may induce a temporary elimination of iron sensing. Hemojuvelin is a coreceptor for bone morphogenetic proteins (BMPs), and inhibition of endogenous BMP signaling reduces hepcidin expression and increases serum iron in mice. Furthermore, Hemojuvelin may play inhibitory roles in prostate cancer by suppressing cell growth, adhesion, migration and invasion.

General readings

Zhu, X., et al. Genet. Epidemiol. 34(2):171-187(2010)
Barton, J.C., et al. Am. J. Hematol. 84(11):710-714(2009)
Zhang, A.S., et al. J. Biol. Chem. 284(34):22580-22589(2009)

18 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

HFE2 / Hemojuvelin antibody

  HFE2 / Hemojuvelin Mouse Monoclonal (1C12) Antibody  
Anti-HFE2 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. Mouse IgG2a 1C12 Purified Hu E, WB
50 µg / €450.00
  OriGene Technologies, Inc.

HFE2 / Hemojuvelin antibody

  Rabbit anti-HFE2 Polyclonal Antibody  
Western blot analysis of extracts of various cell lines, using HFE2 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

HFE2 / Hemojuvelin antibody

  Rabbit Polyclonal Anti-HFE2 Antibody  
WB Suggested Anti-HFE2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: HT1080 cell lysate Rabbit IgG Purified Bov, Can, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

HFE2 / Hemojuvelin (Center) antibody

Immunohistochemistry analysis in formalin fixed and paraffin embedded skeletal muscle reacted with HFE2 / Hemojuvelin Antibody (Center) Cat.-No AP52036PU-N, which was peroxidase conjugated to the secondary antibody and followed by DAB staining. Rabbit Ig Aff - Purified Hu, Ms P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

HFE2 / Hemojuvelin (C-term) antibody

Western blot analysis of HFE2 / Hemojuvelin Antibody (C-term) Cat.-No AP52037PU-N in HepG2 cell line lysates (35ug/lane). HFE2 (arrow) was detected using the purified Pab. Rabbit Ig Aff - Purified Hu F, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

ELISA Kits

Catalog No.    

Mouse Hemojuvelin ELISA Kit

Mouse Hemojuvelin ELISA Kit  
1 kit / €389.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

HFE2 overexpression lysate

HFE2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

HFE2 overexpression lysate

HFE2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, HFE2 (mGFP-tagged)-Human hemochromatosis type 2 (juvenile) (HFE2), transcript variant a, 200 uL, >10^7 TU/mL

Lenti ORF particles, HFE2 (mGFP-tagged)-Human hemochromatosis type 2 (juvenile) (HFE2), transcript variant a, 200 uL, >10^7 TU/mL  
200 µl / €1,020.00
  OriGene Technologies, Inc.

Lenti ORF particles, HFE2 (mGFP-tagged) - Human hemochromatosis type 2 (juvenile) (HFE2), transcript variant b, 200 uL, >10^7 TU/mL

Lenti ORF particles, HFE2 (mGFP-tagged) - Human hemochromatosis type 2 (juvenile) (HFE2), transcript variant b, 200 uL, >10^7 TU/mL  
200 µl / €960.00
  OriGene Technologies, Inc.

Lenti ORF particles, HFE2 (mGFP-tagged)-Human hemochromatosis type 2 (juvenile) (HFE2), transcript variant c, 200 uL, >10^7 TU/mL

Lenti ORF particles, HFE2 (mGFP-tagged)-Human hemochromatosis type 2 (juvenile) (HFE2), transcript variant c, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, HFE2 (mGFP-tagged)-Human hemochromatosis type 2 (juvenile) (HFE2), transcript variant d, 200 uL, >10^7 TU/mL

Lenti ORF particles, HFE2 (mGFP-tagged)-Human hemochromatosis type 2 (juvenile) (HFE2), transcript variant d, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, HFE2 (Myc-DDK-tagged)-Human hemochromatosis type 2 (juvenile) (HFE2), transcript variant a, 200 uL, >10^7 TU/mL

Lenti ORF particles, HFE2 (Myc-DDK-tagged)-Human hemochromatosis type 2 (juvenile) (HFE2), transcript variant a, 200 uL, >10^7 TU/mL  
200 µl / €910.00
  OriGene Technologies, Inc.

Lenti ORF particles, HFE2 (Myc-DDK tagged) - Human hemochromatosis type 2 (juvenile) (HFE2), transcript variant b , 200 uL, >10^7 TU/mL

Lenti ORF particles, HFE2 (Myc-DDK tagged) - Human hemochromatosis type 2 (juvenile) (HFE2), transcript variant b , 200 uL, >10^7 TU/mL  
200 µl / €860.00
  OriGene Technologies, Inc.

Lenti ORF particles, HFE2 (Myc-DDK-tagged)-Human hemochromatosis type 2 (juvenile) (HFE2), transcript variant c, 200 uL, >10^7 TU/mL

Lenti ORF particles, HFE2 (Myc-DDK-tagged)-Human hemochromatosis type 2 (juvenile) (HFE2), transcript variant c, 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Lenti ORF particles, HFE2 (Myc-DDK-tagged)-Human hemochromatosis type 2 (juvenile) (HFE2), transcript variant d, 200 uL, >10^7 TU/mL

Lenti ORF particles, HFE2 (Myc-DDK-tagged)-Human hemochromatosis type 2 (juvenile) (HFE2), transcript variant d, 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Hfe2 (GFP-tagged) - Mouse hemochromatosis type 2 (juvenile) (human homolog) (Hfe2), 200 uL, >10^7 TU/mL

Lenti ORF particles, Hfe2 (GFP-tagged) - Mouse hemochromatosis type 2 (juvenile) (human homolog) (Hfe2), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Hfe2 (Myc-DDK-tagged) - Mouse hemochromatosis type 2 (juvenile) (human homolog) (Hfe2), 200 uL, >10^7 TU/mL

Lenti ORF particles, Hfe2 (Myc-DDK-tagged) - Mouse hemochromatosis type 2 (juvenile) (human homolog) (Hfe2), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

18 Item(s)

per page
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