HFE2 / Hemojuvelin antibody

Principal name

HFE2 / Hemojuvelin antibody

Alternative names for HFE2 / Hemojuvelin antibody

HJV, RGMC, Hemochromatosis type 2 protein, RGM domain family member C

SwissProt ID

Q6ZVN8 (Human), Q7TQ32 (Mouse), Q8N7M5 (Rat)

Gene ID

148738 (HFE2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Flow Cytometry (F), Frozen Sections (C)

Background of HFE2 / Hemojuvelin antibody

The product of this gene is involved in iron metabolism. It may be a component of the signaling pathway which activates hepcidin or it may act as a modulator of hepcidin expression. It could also represent the cellular receptor for hepcidin. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. Defects in this gene are the cause of hemochromatosis type 2A, also called juvenile hemochromatosis (JH). JH is an early-onset autosomal recessive disorder due to severe iron overload resulting in hypogonadotrophic hypogonadism, hepatic fibrosis or cirrhosis and cardiomyopathy, occurring typically before age of 30. [provided by RefSeq]. Transcript Variant: This variant (b) lacks a segment in the 5' UTR and an in-frame portion of the 5' coding region, compared to variant a. The resulting isoform (b) has a shorter N-terminus when compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

Zhu, X., et al. Genet. Epidemiol. 34(2):171-187(2010)
Barton, J.C., et al. Am. J. Hematol. 84(11):710-714(2009)
Zhang, A.S., et al. J. Biol. Chem. 284(34):22580-22589(2009)

18 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

HFE2 / Hemojuvelin antibody

Anti-HFE2 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. Mouse IgG2a 1C12 Purified Hu E, WB
50 µg / €345.00
  OriGene Technologies, Inc.

HFE2 / Hemojuvelin antibody

Western blot analysis of extracts of various cell lines, using HFE2 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

HFE2 / Hemojuvelin antibody

WB Suggested Anti-HFE2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: HT1080 cell lysate Rabbit IgG Purified Bov, Can, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

HFE2 / Hemojuvelin (Center) antibody

Immunohistochemistry analysis in formalin fixed and paraffin embedded skeletal muscle reacted with HFE2 / Hemojuvelin Antibody (Center) Cat.-No AP52036PU-N, which was peroxidase conjugated to the secondary antibody and followed by DAB staining. Rabbit Ig Aff - Purified Hu, Ms P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

HFE2 / Hemojuvelin (C-term) antibody

Western blot analysis of HFE2 / Hemojuvelin Antibody (C-term) Cat.-No AP52037PU-N in HepG2 cell line lysates (35ug/lane). HFE2 (arrow) was detected using the purified Pab. Rabbit Ig Aff - Purified Hu F, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

HFE2 / Hemojuvelin antibody

HFE2 polyclonal antibody (A01), Lot # 060519JCS1 Western Blot analysis of HFE2 expression in U-2 OS ( Cat # L022V1 ). Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

HFE2 / Hemojuvelin antibody

Western Blot analysis of HFE2 expression in transfected 293T cell line (H00148738-T01) by HFE2 MaxPab polyclonal antibody.

Lane 1: HFE2 transfected lysate(34.43 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

HFE2 / Hemojuvelin antibody

HFE2 MaxPab rabbit polyclonal antibody. Western Blot analysis of HFE2 expression in mouse spleen. Rabbit Purified Hu, Ms E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

HFE2 / Hemojuvelin antibody

Immunoperoxidase of monoclonal antibody to HFE2 on formalin-fixed paraffin-embedded human liver. [antibody concentration 3 ug/ml] Mouse IgG2a 1C12 Purified Hu E, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

HFE2 / Hemojuvelin antibody

HFE2 / Hemojuvelin Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

HFE2 / Hemojuvelin antibody

HFE2 / Hemojuvelin Rabbit Purified Hu, Ms, Rt C, P, WB
0.1 ml / €400.00
  Novus Biologicals Inc.

HFE2 / Hemojuvelin antibody

HFE2 / Hemojuvelin Rabbit Aff - Purified Hu WB
50 µg / €440.00
  Novus Biologicals Inc.

HFE2 / Hemojuvelin antibody

Immunohistochemistry-Paraffin: Repulsive Guidance Molecule C Antibody [NBP1-89721] - Immunohistochemical staining of human stomach shows strong cytoplasmic positivity in glandular cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

HFE2 / Hemojuvelin

HFE2 / Hemojuvelin Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

HFE2 / Hemojuvelin

HFE2 / Hemojuvelin Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

HFE2 293T Cell Transient Overexpression Lysate(Denatured)

HFE2 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

HFE2 overexpression lysate

HFE2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Lysates (Overexpressed)

Catalog No.    

HFE2 overexpression lysate

HFE2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

18 Item(s)

per page
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