HGS / HRS antibody

Principal name

HGS / HRS antibody

Alternative names for HGS / HRS antibody

Protein pp110, Hepatocyte growth factor-regulated tyrosine kinase substrate

SwissProt ID

O14964 (Human), Q0V8S0 (Bovin), Q99LI8 (Mouse), Q9JJ50 (Rat)

Gene ID

9146 (HGS), 15239 (Hgs)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Por (Porcine), Can (Canine)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection))

Background of HGS / HRS antibody

The hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs) is a zinc-finger protein that interacts with STAM and undergoes tyrosine phosphorylation in response to IL2, CSF2 or HGF. Hrs is involved in intracellular trafficking and signal transduction and is associated with early endosomes. H contains a phosphatidylinositol 3-phosphate-binding domain that contributes to its endosomal targeting, where Hrs colocalizes with Clathrin via a Clathrin box motif at the carboxy terminus of Hrs. Hrs is essential for ventral folding morphogenesis and shares structual similarity to the yeast protein Vps27p, which is involved in vacuolar protein sorting. The human Hrs gene, which maps to chromosome 17q25, enodes a 777 amino acid protein. In Schwann cells, Hrs colocalizes at endosomes with the tumor suppressor protein schwannomin, suggesting a role for schwannomin in Hrs-mediated cell signaling.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

HGS / HRS antibody

Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit IgG Purified Hu, Ms, Rt E, ICC/IF, P, WB
50 µl / €380.00
  OriGene Technologies GmbH

HGS / HRS antibody

  Goat Polyclonal Antibody against HGS  
TA303100 (2.5µg/ml) staining of paraffin embedded Human Testis. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. Goat Purified Can, Hu, Ms, Rt E, WB
0.1 mg / €360.00
  OriGene Technologies, Inc.

HGS / HRS antibody

  Rabbit polyclonal anti-HGS antibody  
Western blot analysis of extracts from 293 cells and JK cells, using HGS antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 ml / €335.00
  OriGene Technologies, Inc.

HGS / HRS antibody

  Rabbit Polyclonal Anti-HGS Antibody  
Western blot analysis on HepG2 cell lysate using HGS Antibody Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €335.00
  OriGene Technologies, Inc.

HGS / HRS antibody

  HGS mouse monoclonal antibody, clone OTI1C2 (formerly 1C2)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY HGS (RC200609, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-HGS. Mouse IgG2b OTI1C2 Purified Hu WB
0.1 ml / €350.00
  OriGene Technologies, Inc.

TrueMAB

HGS / HRS antibody

  HGS mouse monoclonal antibody, clone OTI3H7 (formerly 3H7)  
Anti-HGS mouse monoclonal antibody (TA505894) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY HGS(RC200609). Mouse IgG2b OTI3H7 Purified Hu ICC/IF, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

HGS / HRS (N-term) antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  OriGene Technologies GmbH

HGS / HRS antibody

Immunohistochemistry analyzes of HRS antibody Cat.-No AP20247PU-N in paraffin-embedded human brain tissue. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €350.00
  OriGene Technologies GmbH

HGS / HRS antibody

Immunohistochemistry analyzes of Hrs antibody (Cat.-No.: AP20509PU-N) in paraffin-embedded Human testis tissue. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €350.00
  OriGene Technologies GmbH

HGS / HRS pTyr334 antibody

Immunohistochemistry analysis of paraffin-embedded human brain, using HRS (Phospho-Tyr334) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
50 µg / €230.00
  Assay Biotech

HGS / HRS pTyr334 antibody

Immunohistochemistry analysis of paraffin-embedded human brain, using HRS (Phospho-Tyr334) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 mg / €330.00
  Assay Biotech

HGS / HRS antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using HRS (Ab-334) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
50 µg / €230.00
  Assay Biotech

HGS / HRS antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using HRS (Ab-334) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 mg / €330.00
  Assay Biotech

HGS / HRS antibody

Immunohistochemistry analysis of paraffin-embedded human testis tissue, using HGS Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
50 µg / €230.00
  Assay Biotech

HGS / HRS antibody

Immunohistochemistry analysis of paraffin-embedded human testis tissue, using HGS Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 mg / €330.00
  Assay Biotech

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

HGS / HRS

  Recombinant protein of human hepatocyte growth factor-regulated tyrosine kinase substrate (HGS)  
HGS / HRS Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €438.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

HGS overexpression lysate

HGS overexpression lysate  
0.1 mg / €295.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, HGS (mGFP-tagged) - Human hepatocyte growth factor-regulated tyrosine kinase substrate (HGS), 200 uL, >10^7 TU/mL

Lenti ORF particles, HGS (mGFP-tagged) - Human hepatocyte growth factor-regulated tyrosine kinase substrate (HGS), 200 uL, >10^7 TU/mL  
200 µl / €1,082.00
  OriGene Technologies, Inc.

Lenti ORF particles, HGS (Myc-DDK tagged) - Human hepatocyte growth factor-regulated tyrosine kinase substrate (HGS) , 200 uL, >10^7 TU/mL

Lenti ORF particles, HGS (Myc-DDK tagged) - Human hepatocyte growth factor-regulated tyrosine kinase substrate (HGS) , 200 uL, >10^7 TU/mL  
200 µl / €969.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Hgs (GFP-tagged) - Mouse HGF-regulated tyrosine kinase substrate (Hgs), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, Hgs (GFP-tagged) - Mouse HGF-regulated tyrosine kinase substrate (Hgs), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,432.00
  OriGene Technologies, Inc.

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