HIC2 / ZBTB30 antibody

Principal name

HIC2 / ZBTB30 antibody

Alternative names for HIC2 / ZBTB30 antibody

HIC-2, HRG22, KIAA1020, HIC3, HIC-3, Hypermethylated in cancer 2 protein, HIC1-related gene on chromosome 22, Zinc finger and BTB domain-containing protein 30

SwissProt ID

Q96JB3 (Human), Q9JLZ6 (Mouse)

Gene ID

23119 (HIC2), 58180 (Hic2)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Ms (Mouse), Rt (Rat), Por (Porcine), GP (Guinea Pig), Rb (Rabbit), Eq (Equine), Ze (Zebrafish)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of HIC2 / ZBTB30 antibody

Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. HIC-2 (hypermethylated in cancer 2) possesses zinc finger motifs that are thought to be important for DNA-binding and also has a BTB/POZ domain at the N-terminus, which is thought to be important for protein-protein binding, as well as for the binding of transcription factors. HIC-2 is also known as Hic-3, HIC1-related gene on chromosome 22 or Zinc finger and BTB domain-containing protein 30, and is a 615 amino acid protein that is expressed as two isoforms produced by alternative splicing. HIC-2 is highly expressed in cerebellum and is localized to the nucleus in cells. HIC-2 contains a short amino acid sequence that is thought to interact with CtBP, a transcriptional repressor. The gene sequence associated with HIC-2 is thought to be a target for miRNAs (microRNAs) which are expressed in many cancers, suggesting that HIC-2 could possess tumor suppressor capabilities.

General readings

Collins,J.E., Genome Biol. 5 (10), R84 (2004)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

HIC2 / ZBTB30 antibody

Huh-7; . Sample Type :. Huh-7. . Primary Antibody Dilution:. 4 ug/ml . Secondary Antibody :. Anti-rabbit Alexa 546 . Secondary Antibody Dilution:. 2 ug/ml . Gene Name :. HIC2; HIC2 antibody - middle region (ARP31802_P050) in Huh-7 cells using Immunofluorescence Rabbit Aff - Purified Bov, Can, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

HIC2 / ZBTB30 (188-200) antibody

(0.1ug/ml) staining of HepG2 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Por, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

HIC2 / ZBTB30 antibody

WB Suggested Anti-HIC2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: Human brain Rabbit IgG Purified Bov, Can, Hu, Ms, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

HIC2 / ZBTB30 antibody

WB Suggested Anti-HIC2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: Human Placenta Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

HIC2 / ZBTB30 antibody

WB Suggested Anti-HIC2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: THP-1 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

HIC2 / ZBTB30 antibody

HIC2 / ZBTB30 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

HIC2 / ZBTB30 antibody

Immunofluorescence of purified MaxPab antibody to HIC2 on HepG2 cell. [antibody concentration 10 ug/ml] Mouse Purified Hu E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

HIC2 / ZBTB30 antibody

Hum. Fetal Brain; Host: Rabbit . Target Name: HIC2 . Sample Tissue: Human Fetal Brain . Antibody Dilution: 1.0ug/ml.; HIC2 antibody - middle region (ARP32981_P050) in Hum. Fetal Brain cells using Western Blot Rabbit Aff - Purified Bov, Can, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

HIC2 / ZBTB30 antibody

Human Placenta; WB Suggested Anti-HIC2 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: Human Placenta; HIC2 antibody - N-terminal region (ARP39170_P050) in Human Placenta cells using Western Blot Rabbit Aff - Purified Bov, Can, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

HIC2 / ZBTB30 (C-term) antibody

HIC2 / ZBTB30 Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

HIC2 / ZBTB30 antibody

Western blot analysis of HIC2 expression in HepG2 (A); HeLa (B); NIH3T3 (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

HIC2 / ZBTB30 antibody

Western blot analysis of HIC2 expression in HepG2 (A); HeLa (B); NIH3T3 (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

HIC2 / ZBTB30 antibody

Western blot analysis of HIC2 expression in HepG2 (A); HeLa (B); NIH3T3 (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

HIC2 / ZBTB30 antibody

HIC2 / ZBTB30 Rabbit IgG Aff - Purified Hu, Ms WB
50 µg / €680.00
  Funakoshi Co., Ltd.

HIC2 / ZBTB30 antibody

Immunohistochemistry-Paraffin: HIC2 Antibody [NBP1-81710] - Immunohistochemical staining of human placenta shows strong cytoplasmic positivity in trophoblastic cells. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

HIC2 / ZBTB30 (full length, N-term HIS tag)

HIC2 / ZBTB30 Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
50 µg / €199.00
  OriGene Technologies, Inc.

HIC2 / ZBTB30

HIC2 / ZBTB30 Human Purified
2 µg / €300.00
  Abnova Taiwan Corp.

HIC2 / ZBTB30

HIC2 / ZBTB30 Human
2 µg / €300.00
  Abnova Taiwan Corp.

HIC2 / ZBTB30

HIC2 / ZBTB30 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

HIC2 / ZBTB30

HIC2 / ZBTB30 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

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