HINT2 antibody

Principal name

HINT2 antibody

Alternative names for HINT2 antibody

HINT-2, HINT-3, HIT-17kDa, PKCI-1-related HIT protein, Histidine triad nucleotide-binding protein 2

SwissProt ID

Q8SQ21 (Bovin), Q9BX68 (Human), Q9D0S9 (Mouse)

Gene ID

84681 (HINT2)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit), Ms (Mouse), Rt (Rat), Eq (Equine)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Flow Cytometry (F)

Background of HINT2 antibody

Histidine triad nucleotide binding protein 2 (HINT2) is a mitochondrial protein. This protein is an AMP-lysine hydrolase and phosphoamidase and may contribute to tumor suppression. This protein is a member of the HIT superfamily and Hint subfamily, which are characterized as nucleotide hydrolases and transferases that act on the alpha-phosphate of ribonucleotides. HINT2 regulates steroidogenesis through calcium-dependent and calcium-independent siglling pathways that may serve to maintain a favorable mitochondrial potential. Its role in calcium homeostasis may also contribute to its proapoptotic function in hepatocytes and other non-steroidogenic cells, though the exact mechanism remains unclear.

General readings

Maize KM., et al. (2013) The FEBS journal. 280(14): 3389-3398.Lenglet S., et al. (2008) Endocrinology. 149(11): 5461-5469.Martin J., et al. (2006) Gastroenterology. 130(7): 2179-2188.Lee LR., et al. (2013) Cancer prevention research. 6(7): 731-743.

19 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

HINT2 antibody

Predicted cell location: Cytoplasm. Positive control: Human colon cancer tissue. Recommended dilution: 1/10-50  The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using HINT2 antibody at dilution 1/20, on the right is treated with the synthetic peptide. (Original magnification:x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

HINT2 antibody

Predicted cell location: Cytoplasm. Positive control: Human breast and colon cancer tissue. Recommended dilution: 1/25-100  The image on the left is immunohistochemistry of paraffin-embedded Human breast and colon cancer tissue using HINT2 antibody at dilution 1/60, on the right is treated with the synthetic peptide. (Original magnification:x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

HINT2 antibody

WB Suggested Anti-HINT2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:1562500; Positive Control: Human brain Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Por, Rb WB
50 µg / €325.00
  OriGene Technologies, Inc.

HINT2 antibody

The recombinant human HINT2 (50ng) and Cell lysates (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human HINT2 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

Lane 1. : HINT2 Recombinant protein
Lane 2. : HepG2 cell lysate 
Lane 3. : U87MG cell lysate 
Lane 4. : Mouse brain lysate Mouse IgG1 AT5B10 Purified Hu E, F, WB
0.1 ml / €310.00
  Acris Antibodies GmbH

HINT2 antibody

The recombinant human HINT2 (50ng) and Cell lysates (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human HINT2 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

Lane 1. : HINT2 Recombinant protein
Lane 2. : HepG2 cell lysate 
Lane 3. : U87MG cell lysate 
Lane 4. : Mouse brain lysate Mouse IgG1 AT5B10 Purified Hu E, F, WB
50 µl / €220.00
  Acris Antibodies GmbH

HINT2 antibody

HINT2 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

HINT2 antibody

HINT2 Mouse IgG2a 4E11 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

HINT2 antibody

HINT2 Mouse IgG2a 1C2 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

HINT2 (C-term) antibody

Human Brain; WB Suggested Anti-HINT2 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: Human brain; HINT2 antibody - C-terminal region (ARP60265_P050) in Human Brain cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

HINT2 antibody

HINT2 Rabbit Aff - Purified Hu WB
50 µg / €440.00
  Novus Biologicals Inc.

HINT2 antibody

Immunohistochemistry-Paraffin: HINT2 Antibody [NBP1-86024] - Immunohistochemical staining of human kidney shows strong cytoplasmic positivity in tubular cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

HINT2

HINT2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

HINT2 (18-163, His-tag)

HINT2 Human Purified > 90 % by SDS - PAGE E. coli
0.25 mg / €730.00
  Acris Antibodies GmbH

HINT2 (18-163, His-tag)

HINT2 Human Purified > 90 % by SDS - PAGE E. coli
50 µg / €300.00
  Acris Antibodies GmbH

HINT2

HINT2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

HINT2

HINT2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

HINT2

HINT2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

HINT2

HINT2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

HINT2 overexpression lysate

HINT2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

19 Item(s)

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