HIRA / TUPLE1 antibody

Principal name

HIRA / TUPLE1 antibody

Alternative names for HIRA / TUPLE1 antibody

DGCR1, HIR, TUP1-like enhancer of split protein 1, HIR histone cell cycle regulation defective homolog A

SwissProt ID

P54198 (Human), P79987 (Chick), Q61666 (Mouse), Q8QFR2 (Xenla)

Gene ID

7290 (HIRA), 15260 (Hira)

Available reactivities

S. cerevisiae (Saccharomyces cerevisiae), Hu (Human), Ms (Mouse), Can (Canine), Eq (Equine), GP (Guinea Pig), Rb (Rabbit), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of HIRA / TUPLE1 antibody

Hira (UniProtKB/Swiss-Prot entry P54198) is a histone chaperone that cooperates with ASF1A to promote replication-independent chromatin assembly. It is important for histone regulation and is required for the periodic repression of histone gene transcription during the cell cycle. Hira plays an important role in the formation of transcriptiolly silent senescence-associated heterochromatic foci (SAHF). SAHF, which contain heterochromatin proteins such as HP1, are believed to repress expression of proliferation-promoting genes, leading to the irreversible cell cycle changes that occur in senescent cells. Interaction between HIRA and ASF1A is the rate limiting step in the formation of SAHF. Hira is also thought to be involved in certain haploinsufficiency syndromes such as DiGeorge syndrome. Insufficient production of Hira protein may disrupt normal embryonic development.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

HIRA / TUPLE1 antibody

  Rabbit polyclonal HIRA (Thr555) antibody(Phospho-specific)  
Immunofluorescence analysis of HeLa cells, using HIRA (Phospho-Thr555) antibody.The picture on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, ICC/IF
0.1 ml / €325.00
  OriGene Technologies, Inc.

HIRA / TUPLE1 antibody

  Rabbit polyclonal HIRA Antibody (Center)  
HIRA Antibody (Center) (Cat. #TA324826) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the HIRA antibody detected the HIRA protein (arrow). Rabbit Ig Purified Hu WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

HIRA / TUPLE1 antibody

  Rabbit Polyclonal Anti-Hira Antibody  
WB Suggested Anti-Hira Antibody Titration: 0.2-1 ug/ml; Positive Control: Mouse Brain Rabbit IgG Purified Can, Eq, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

HIRA / TUPLE1 antibody

  Rabbit Polyclonal Hira Antibody  
WB was performed on whole cell lysates from mouse fibroblasts (NIH3T3) and embryonic stem cells (E14Tg2a) with the antibody against mouse Hira, diluted 1:1,000 in BSA/PBS-Tween. The molecular weight marker (M, in kDa) is shown on the left; the location of the protein of interest (112 kDa) is indicated on the right. Rabbit IgG Purified Ms E
0.1 ml / €325.00
  OriGene Technologies, Inc.

HIRA / TUPLE1 antibody

Figure 1. Western blot analysis using TUP1 antibody (AM05331PU-N) on recombinant TUP1 protein (amino acids 1-200) expressed in Mav108 cells. Mouse IgG 10 Purified S. cerevisiae WB
0.1 mg / €370.00
  Acris Antibodies GmbH

HIRA / TUPLE1 pThr555 antibody

Immunofluorescence analysis of HeLa cells, using HIRA (Phospho-Thr555) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, ICC/IF
50 µg / €230.00
  Assay Biotech

HIRA / TUPLE1 pThr555 antibody

Immunofluorescence analysis of HeLa cells, using HIRA (Phospho-Thr555) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, ICC/IF
0.1 mg / €330.00
  Assay Biotech

HIRA / TUPLE1 antibody

Immunohistochemistry analysis of paraffin-embedded human tonsil tissue, using HIRA (Ab-555) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, P
50 µg / €230.00
  Assay Biotech

HIRA / TUPLE1 antibody

Immunohistochemistry analysis of paraffin-embedded human tonsil tissue, using HIRA (Ab-555) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, P
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

Hira - mouse gene knockout kit via CRISPR

Hira - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Hira - mouse gene knockout kit via CRISPR

Hira - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Hira - mouse gene knockout kit via CRISPR

Hira - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Hira - mouse gene knockout kit via CRISPR

Hira - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, HIRA (mGFP-tagged)-Human HIR histone cell cycle regulation defective homolog A (S. cerevisiae) (HIRA), 200 uL, >10^7 TU/mL

Lenti ORF particles, HIRA (mGFP-tagged)-Human HIR histone cell cycle regulation defective homolog A (S. cerevisiae) (HIRA), 200 uL, >10^7 TU/mL  
200 µl / €1,320.00
  OriGene Technologies, Inc.

Lenti ORF particles, HIRA (Myc-DDK-tagged)-Human HIR histone cell cycle regulation defective homolog A (S. cerevisiae) (HIRA), 200 uL, >10^7 TU/mL

Lenti ORF particles, HIRA (Myc-DDK-tagged)-Human HIR histone cell cycle regulation defective homolog A (S. cerevisiae) (HIRA), 200 uL, >10^7 TU/mL  
200 µl / €1,180.00
  OriGene Technologies, Inc.

15 Item(s)

per page
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