Histamine H1 receptor antibody

Principal name

Histamine H1 receptor antibody

Alternative names for Histamine H1 receptor antibody

HRH1, HR-H1, Histamine H1 receptor

SwissProt ID

P30546 (Bovin), P31390 (Rat), P35367 (Human), P70174 (Mouse)

Gene ID

3269 (HRH1), 24448 (Hrh1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Mky (Monkey), Chimp (Chimpanzee), Gorilla, Chk (Chicken), Eq (Equine), Hst (Hamster), Por (Porcine), Rb (Rabbit)

Available hosts

Rabbit, Goat, Mouse

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C)

Background of Histamine H1 receptor antibody

Histamine (2-[4-imidazole]ethylamine) is a low-molecular-weight amine synthesized from L-histidine. It is produced by various cells throughout the body, including central nervous system neurons, gastric mucosa parietal cells, mast cells, basophils and lymphocytes. Histamine is a major biological mediator whose functions include, among many others, regulation of vascular smooth muscle, immune regulation, regulation of sleep-wake cycles and regulation of gastric acid secretion. The biological effects of histamine are mediated through four receptors (H1- H4 Histamine receptors) all of which belong to the 7-transmembrane domain, G protein-coupled receptor (GPCR) superfamily. H1 receptors couple to Gq/G11 proteins leading to phospholipase C activation, inositol phosphate production and calcium mobilization. H1 receptors are expressed in many cell types including endothelial and smooth muscle cells where they mediate vasodilatation and increased vascular permeability effects. H1 receptors are widely distributed through the brain where the mediate sleep-wake cycles and regulate cognitive functions. H1 receptors are expressed in a several cell populations involved in the immune response, including T-cells and B-cells, monocytes and eosinophiles. H1 anti-histamine compounds have been available for almost thirty years and are among the most commonly used medication for conditions such as allergic inflammation. In addition, H1 anti-histamines are also prescribed for the treatment of insomnia and algesia.

General readings

Kawakami N, Miyoshi K, Horio S, Fukui H. Beta(2)-adrenergic receptor-mediated histamine H(1) receptor down-regulation: another possible advantage of beta(2) agonists in asthmatic therapy.J Pharmacol Sci. 2004 Apr;94(4):449-58. PMID: 15107586

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Histamine H1 receptor (2nd extracell. dom.) antibody

Anti-HRH1 / Histamine H1 Receptor antibody IHC of human Vessel. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Hu, Mky P
50 µg / €345.00
  OriGene Technologies, Inc.

Histamine H1 receptor antibody

TA303207 (0.5µg/ml) staining of Human Heart lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Histamine H1 receptor antibody

Anti-HRH1 / H1 Receptor antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 4 ug/ml. Rabbit IgG Purified Hu
50 µg / €345.00
  OriGene Technologies, Inc.

Histamine H1 receptor antibody

Anti-HRH1 / Histamine H1 Receptor antibody IHC of human small intestine, smooth muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. Goat Purified Bov, Can, Chimp, Chk, Eq, Gorilla, Hst, Hu, Mky, Ms, Por, Rb, Rt P
50 µg / €345.00
  OriGene Technologies, Inc.

Histamine H1 receptor antibody

Western blot analysis of rat heart membranes (lanes 1 and 3) and rat basophilic leukemia (RBL) cell lysates (lanes 2 and 4): 1, 2. Anti-H1 Histamine Receptor antibody, (1:200). 3, 4. Anti-H1 Histamine Receptor antibody, preincubated with the control peptide antigen. Rabbit Purified Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

Histamine H1 receptor antibody

Western blot (WB) analysis of Histamine H1 Receptor antibody in extracts from COLO205 cells. Rabbit Aff - Purified Hu E, ICC/IF, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Histamine H1 receptor (C-term) antibody

AP23217PU-N Histamine H1  Receptor antibody staining of Paraffin Embedded Human Colon at 4 µg/ml. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining. Goat Aff - Purified Bov, Can, Hu, Ms, Rt E, P
0.1 mg / €340.00
  Acris Antibodies GmbH

Histamine H1 receptor pSer398 antibody

Immunofluorescence staining of methanol-fixed HuvEc cells using Histamine H1 Receptor (Phospho-Ser398) Antibody AP55724PU-N. Rabbit Aff - Purified Hu, Ms ICC/IF
0.1 ml / €340.00
  Acris Antibodies GmbH

Histamine H1 receptor pSer398 antibody

Immunofluorescence staining of methanol-fixed HuvEc cells using Histamine H1 Receptor (Phospho-Ser398) Antibody AP55724PU-N. Rabbit Aff - Purified Hu, Ms ICC/IF
50 µl / €270.00
  Acris Antibodies GmbH

Histamine H1 receptor Control Peptide

Histamine H1 receptor Purified
50 µg / €220.00
  Acris Antibodies GmbH

Histamine H1 receptor antibody

Proximity Ligation Analysis (PLA) of protein-protein interactions between IL6 and HRH1. HeLa cells were stained with anti-IL6 rabbit purified polyclonal 1:1200 and anti-HRH1 mouse monoclonal antibody 1:50. Signals were detected by Duolink® 30 Detection Kit 613(red), and nuclei were counterstained with DAPI (blue). Each red dot represents the detection of protein-protein interaction complex. Mouse IgG1 3D1 Purified Hu E
0.1 mg / €370.00
  Abnova Taiwan Corp.

Histamine H1 receptor antibody

Histamine H1 receptor Goat Hu E
0.1 mg / €400.00
  Abnova Taiwan Corp.

Histamine H1 receptor antibody

HRH1 polyclonal antibody ( Cat # PAB7234 ) ( 0.5 µg/ml ) staining of human heart lysate ( 35 µg protein in RIPA buffer ) . Primary incubation was 1 hour. Detected by chemiluminescence. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

Histamine H1 receptor pSer398 antibody

Immunofluorescence analysis of HuvEc cells, using Histamine H1 Receptor (Phospho-Ser398) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF
50 µg / €205.00
  Assay Biotech

Histamine H1 receptor pSer398 antibody

Immunofluorescence analysis of HuvEc cells, using Histamine H1 Receptor (Phospho-Ser398) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF
0.1 mg / €310.00
  Assay Biotech

Histamine H1 receptor antibody

Immunofluorescence analysis of LOVO cells, using HRH1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, ICC/IF, WB
50 µg / €205.00
  Assay Biotech

Histamine H1 receptor antibody

Immunofluorescence analysis of LOVO cells, using HRH1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, ICC/IF, WB
0.1 mg / €310.00
  Assay Biotech

Histamine H1 receptor antibody

Immunohistochemistry-Frozen: HRH1 Antibody [NB600-795] - (4µg/ml) staining of paraffin embedded Human Colon. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining. Goat IgG Aff - Purified Hu C, E, P
0.1 mg / €400.00
  Novus Biologicals Inc.

Histamine H1 receptor Control Peptide

Histamine H1 receptor E
0.1 mg / €340.00
  Novus Biologicals Inc.

Histamine H1 receptor antibody

Western Blot: Histamine H1 Receptor Antibody [NBP1-00868] - Western blot (WB) analysis of Histamine H1 Receptor (K179) antibody in extracts from COLO205 cells Rabbit Aff - Purified Hu ICC/IF, WB
0.1 mg / €420.00
  Novus Biologicals Inc.

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