Histamine H1 receptor antibody

Principal name

Histamine H1 receptor antibody

Alternative names for Histamine H1 receptor antibody

HRH1, HR-H1, Histamine H1 receptor

SwissProt ID

P30546 (Bovin), P31390 (Rat), P35367 (Human), P70174 (Mouse)

Gene ID

3269 (HRH1), 24448 (Hrh1), 15465

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Mky (Monkey), Chimp (Chimpanzee), Chk (Chicken), Eq (Equine), Hst (Hamster), Por (Porcine), Rb (Rabbit), Gorilla

Available hosts

Goat, Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of Histamine H1 receptor antibody

Histamine (2-[4-imidazole]ethylamine) is a low-molecular-weight amine synthesized from L-histidine. It is produced by various cells throughout the body, including central nervous system neurons, gastric mucosa parietal cells, mast cells, basophils and lymphocytes. Histamine is a major biological mediator whose functions include, among many others, regulation of vascular smooth muscle, immune regulation, regulation of sleep-wake cycles and regulation of gastric acid secretion. The biological effects of histamine are mediated through four receptors (H1- H4 Histamine receptors) all of which belong to the 7-transmembrane domain, G protein-coupled receptor (GPCR) superfamily. H1 receptors couple to Gq/G11 proteins leading to phospholipase C activation, inositol phosphate production and calcium mobilization. H1 receptors are expressed in many cell types including endothelial and smooth muscle cells where they mediate vasodilatation and increased vascular permeability effects. H1 receptors are widely distributed through the brain where the mediate sleep-wake cycles and regulate cognitive functions. H1 receptors are expressed in a several cell populations involved in the immune response, including T-cells and B-cells, monocytes and eosinophiles. H1 anti-histamine compounds have been available for almost thirty years and are among the most commonly used medication for conditions such as allergic inflammation. In addition, H1 anti-histamines are also prescribed for the treatment of insomnia and algesia.

General readings

Bryce PJ, Mathias CB, Harrison KL, Watanabe T, Geha RS, Oettgen HC.
The H1 histamine receptor regulates allergic lung responses.
J Clin Invest. 2006 Jun;116(6):1624-32. Epub 2006 May 4.
PMID: 16680192

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Histamine H1 receptor (2nd extracell. dom.) antibody

  HRH1 / H1 Receptor Rabbit Polyclonal (Extracellular Domain) Antibody  
Anti-HRH1 / Histamine H1 Receptor antibody IHC of human Vessel. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Hu, Mky P
50 µg / €400.00
  OriGene Technologies, Inc.

Histamine H1 receptor antibody

  Goat Polyclonal Antibody against HRH1  
TA303207 (0.5µg/ml) staining of Human Heart lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Histamine H1 receptor antibody

  Rabbit polyclonal Histamine H1 Receptor (Ser398)(Phospho-specific)  
Immunofluorescence analysis of HuvEc cells, using Histamine H1 Receptor (Phospho-Ser398) antibody.The picture on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, ICC/IF
0.1 ml / €325.00
  OriGene Technologies, Inc.

Histamine H1 receptor antibody

  HRH1 / H1 Receptor Rabbit Polyclonal (Cytoplasmic Domain) Antibody  
Anti-HRH1 / H1 Receptor antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 4 ug/ml. Rabbit IgG Purified Hu
50 µg / €400.00
  OriGene Technologies, Inc.

Histamine H1 receptor antibody

  HRH1 / H1 Receptor Goat Polyclonal (C-Terminus) Antibody  
Anti-HRH1 / Histamine H1 Receptor antibody IHC of human small intestine, smooth muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. Goat Purified Bov, Can, Chimp, Chk, Eq, Gorilla, Hst, Hu, Mky, Ms, Por, Rb, Rt P
50 µg / €400.00
  OriGene Technologies, Inc.

Histamine H1 receptor antibody

  Rabbit Polyclonal Anti-H1 Histamine Receptor  
Western blot analysis of rat heart membranes (lanes 1 and 3) and rat basophilic leukemia (RBL) cell lysates (lanes 2 and 4): 1, 2. Anti-H1 Histamine Receptor antibody, (1:200). 3, 4. Anti-H1 Histamine Receptor antibody, preincubated with the control peptide antigen. Rabbit Purified Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

Histamine H1 receptor antibody

  Rabbit Polyclonal Anti-HRH1 Antibody  
Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane: Human normal colon tissue, Primary antibody: (HRH1 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes Rabbit IgG Purified Hu E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Histamine H1 receptor antibody

Western blot (WB) analysis of Histamine H1 Receptor antibody in extracts from COLO205 cells. Rabbit Aff - Purified Hu E, ICC/IF, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Histamine H1 receptor (C-term) antibody

AP23217PU-N Histamine H1  Receptor antibody staining of Paraffin Embedded Human Colon at 4 µg/ml. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining. Goat Aff - Purified Bov, Can, Hu, Ms, Rt E, P
0.1 mg / €350.00
  Acris Antibodies GmbH

Histamine H1 receptor pSer398 antibody

Immunofluorescence staining of methanol-fixed HuvEc cells using Histamine H1 Receptor (Phospho-Ser398) Antibody AP55724PU-N. Rabbit Aff - Purified Hu, Ms ICC/IF
0.1 ml / €340.00
  Acris Antibodies GmbH

Histamine H1 receptor pSer398 antibody

Immunofluorescence staining of methanol-fixed HuvEc cells using Histamine H1 Receptor (Phospho-Ser398) Antibody AP55724PU-N. Rabbit Aff - Purified Hu, Ms ICC/IF
50 µl / €270.00
  Acris Antibodies GmbH

Histamine H1 receptor pSer398 antibody

Immunofluorescence analysis of HuvEc cells, using Histamine H1 Receptor (Phospho-Ser398) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF
50 µg / €230.00
  Assay Biotech

Histamine H1 receptor pSer398 antibody

Immunofluorescence analysis of HuvEc cells, using Histamine H1 Receptor (Phospho-Ser398) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF
0.1 mg / €330.00
  Assay Biotech

Histamine H1 receptor antibody

Immunofluorescence analysis of LOVO cells, using HRH1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, ICC/IF, WB
50 µg / €230.00
  Assay Biotech

Histamine H1 receptor antibody

Immunofluorescence analysis of LOVO cells, using HRH1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, ICC/IF, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

Hrh1 - mouse gene knockout kit via CRISPR

Hrh1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Hrh1 - mouse gene knockout kit via CRISPR

Hrh1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Hrh1 - mouse gene knockout kit via CRISPR

Hrh1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Hrh1 - mouse gene knockout kit via CRISPR

Hrh1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

HRH1 overexpression lysate

HRH1 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

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