Histamine H4 receptor antibody
Principal name
Histamine H4 receptor antibody
Alternative names for Histamine H4 receptor antibody
HH4R, GPCR105, HRH4, G-protein coupled receptor 105, GPRv53, SP9144, AXOR35, Pfi-013
Ncbi ID
NP_001137300.1, 9606, NM_021624, NP_694727.1, NM_153087, NM_131909, NM_001160166
Available reactivities
Available hosts
Available applications
Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Western blot / Immunoblot (WB)
Background of Histamine H4 receptor antibody
Histamine (2-[4-imidazole]ethylamine) is a low-molecular-weight amine synthesized from L-histidine. It is produced by various cells throughout the body, including central nervous system neurons, gastric mucosa parietal cells, mast cells, basophils and lymphocytes. Histamine is a major biological mediator whose functions include, among many others, regulation of vascular smooth muscle, immune regulation, regulation of sleep-wake cycles and regulation of gastric acid secretion. The biological effects of histamine are mediated through four receptors (H1- H4 Histamine receptors) all of which belong to the 7-transmembrane domain, G protein-coupled receptor (GPCR) superfamily. H4 Histamine Receptor couples to Gi/G0 proteins and receptor activation leads to inhibition of adenylate cyclase, mobilisation of calcium from intracellular stores and activation of the mitogen-activated protein kise (MAPK) cascade. H4 Histamine Receptor is largely expressed in haemopoietic cells including mast cells, eosinophils, dendritic cells and T lymphocytes. H4 Histamine Receptors modulate eosinophil migration and the selective recruitment of mast cells leading to amplification of histamine-mediated immune responses. In addition, H4 Histamine Receptors are involved in dendritic cell activation and the regulation of T lymphocyte cytokine production. These studies indicate that H4 Histamine Receptor is an attractive therapeutic target for the treatment of inflammatory disorders, such as allergy, asthma, chronic pruritus and autoimmune diseases.











Primary Antibodies
Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
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TA308703 | Histamine H4 receptor antibody |
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Rabbit polyclonal antibody to Histamine H4 Receptor (histamine receptor H4) | |||||||
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Rabbit | IgG | Aff - Purified | Hu | WB |
0.1 ml /
€416.00
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OriGene Technologies, Inc. | |||||||
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TA315695 | Histamine H4 receptor antibody |
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Rabbit polyclonal anti-HRH4 antibody | |||||||
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Rabbit | IgG | Purified | Hu | E, ICC/IF |
0.1 ml /
€335.00
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OriGene Technologies, Inc. | |||||||
TA315696 | Histamine H4 receptor antibody |
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Rabbit polyclonal anti-KR2_VZVD antibody | |||||||
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Rabbit | IgG | Purified | Hu | E, WB |
0.1 ml /
€335.00
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OriGene Technologies, Inc. | |||||||
TA328667 | Histamine H4 receptor antibody |
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Rabbit Polyclonal Anti-Human H4 Histamine Receptor (extracellular) | |||||||
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Rabbit | Purified | Hu | WB |
0.2 ml /
€622.00
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OriGene Technologies, Inc. | |||||||
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TA340671 | Histamine H4 receptor (1st Cytopl. Dom.) antibody |
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Rabbit Polyclonal Anti-HRH4 Antibody (Cytoplasmic Domain) | |||||||
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Rabbit | Aff - Purified | Bear, Bov, Can, Eq, Hu, Mky, Ms, Op, Platypus, Prim, Rb, Rt | P |
50 µg /
€400.00
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OriGene Technologies, Inc. | |||||||
TA340840 | Histamine H4 receptor antibody |
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Rabbit Polyclonal Anti-HRH4 Antibody (Extracellular Domain) | |||||||
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Rabbit | Purified | Hu, Mky |
50 µg /
€400.00
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OriGene Technologies, Inc. | |||||||
TA340989 | Histamine H4 receptor antibody |
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Rabbit Polyclonal Anti-HRH4 Antibody (Cytoplasmic Domain) | |||||||
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Rabbit | Purified | Hu, Mky |
50 µg /
€400.00
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OriGene Technologies, Inc. | |||||||
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SP4670P | Histamine H4 receptor (C-term) antibody |
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Rabbit | Aff - Purified | Hu | E, ICC/IF, P |
50 µg /
€380.00
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Acris Antibodies GmbH | |||||||
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G372-1 | Histamine H4 receptor antibody |
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Rabbit | Aff - Purified | Hu | E, ICC/IF |
50 µg /
€230.00
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Assay Biotech | |||||||
G372-2 | Histamine H4 receptor antibody |
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Rabbit | Aff - Purified | Hu | E, ICC/IF |
0.1 mg /
€330.00
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Assay Biotech |
CRISPR
Catalog No. | Species | Donor Vector | |
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KN212974 | HRH4 - human gene knockout kit via CRISPR |
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Human | GFP-Puro |
1 kit /
€1,290.00
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OriGene Technologies, Inc. | |||
KN212974BN | HRH4 - human gene knockout kit via CRISPR |
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Human | mBFP-Neo |
1 kit /
€1,290.00
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OriGene Technologies, Inc. | |||
KN212974LP | HRH4 - human gene knockout kit via CRISPR |
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Human | Luciferase-Puro |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. | |||
KN212974RB | HRH4 - human gene knockout kit via CRISPR |
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Human | RFP-BSD |
1 kit /
€1,290.00
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OriGene Technologies, Inc. | |||
KN307945 | Hrh4 - mouse gene knockout kit via CRISPR |
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Mouse | GFP-Puro |
1 kit /
€1,290.00
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OriGene Technologies, Inc. | |||
KN307945BN | Hrh4 - mouse gene knockout kit via CRISPR |
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Mouse | mBFP-Neo |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. | |||
KN307945LP | Hrh4 - mouse gene knockout kit via CRISPR |
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Mouse | Luciferase-Puro |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. | |||
KN307945RB | Hrh4 - mouse gene knockout kit via CRISPR |
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Mouse | RFP-BSD |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. |
Lysates
Catalog No. | ||
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LY411975 | HRH4 overexpression lysate |
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0.1 mg /
€295.00
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OriGene Technologies, Inc. |
Human Lenti ORF Particles
Catalog No. | ||
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RC212974L2V | Lenti ORF particles, HRH4 (mGFP-tagged) - Human histamine receptor H4 (HRH4), transcript variant 1, 200 uL, >10^7 TU/mL |
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200 µl /
€1,082.00
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OriGene Technologies, Inc. | ||