Histone H2A antibody

Principal name

Histone H2A antibody

Alternative names for Histone H2A antibody

H2A Histone Family, HIST1H2A

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Amph (Amphibian), Mam (Mammalia), Xen (Xenopus), Hst (Hamster)

Available hosts

Rabbit, Mouse

Available applications

Immunoprecipitation (IP), Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of Histone H2A antibody

The nucleosome is made up of four core histone proteins (H2A, H2B, H3 and H4) and is the primary building block of chromatin. The N-terminal tail of core histones undergoes multIPPle different post-translational modifications including acetylation, phosphorylation, ubiquitination, methylation and ADP-ribosylation. These modifications occur in response to cell signal stimuli and have a direct effect on gene expression. The role of histone variants, and specially those of H3 and H2A, in various nuclear processes has been long appreciated. There are at least three different families of H2A variants present in a variety of organisms from yeast to mammals, and the degree of conservation among members of each family is greater than that of the canonical H2A. H2AX is thought to play a role in DNA double-strand break repair; the serine in the SQEY motif of H2AX is phosphorylated at the site of the DNA damage and serves as a signal for the recruitment of repair proteins. Macro H2A1, another H2A variant, has been shown to have a role in X-chromosome inactivation and dosage compensation in mammals, where it is found to localize to the inactive X after silencing has been established.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Histone H2A antibody

Immunocytochemical detection of Histone H2A on 4% PFA fixed HeLa cells with AM26685AF-N. Mouse IgG2b C10037 Azide Free Hst, Hu, Ms, Rt ICC/IF, IP, WB
0.1 mg / €360.00
  Acris Antibodies GmbH

Histone H2A antibody

Immunohistochemistry (IHC) analyzes of Histone H2A antibody (Cat.-No.: AP06486PU-N) in paraffin-embedded Human breast carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt P
0.1 mg / €350.00
  Acris Antibodies GmbH

Histone H2A (acetyl K5) antibody

Histone H2A Rabbit Serum Amph, Mam E, ICC/IF, IP, P, WB
0.1 ml / €660.00
  Acris Antibodies GmbH

Histone H2A antibody

Histone H2A Rabbit IgG Serum Mam E, ICC/IF, IP, P, WB
50 µl / €400.00
  Novus Biologicals Inc.

Histone H2A antibody

Histone H2A Rabbit IgG Purified Hu, Ms, Rt P
0.1 mg / €420.00
  Novus Biologicals Inc.

5 Item(s)

per page
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