HLA class I A-2 alpha / HLA-A2 antibody

Principal name

HLA class I A-2 alpha / HLA-A2 antibody

Alternative names for HLA class I A-2 alpha / HLA-A2 antibody

HLAA2, MHC class I antigen A-2, HLA class I histocompatibility antigen, A-2 alpha chain

SwissProt ID

P01892 (Human), Q9TQH5 (Human)

Gene ID

100507703 (LOC100507703)

Available reactivities

Hu (Human)

Available hosts

Mouse

Available applications

Frozen Sections (C), Functional assay (FN), Immunoprecipitation (IP), Flow Cytometry (F)

Background of HLA class I A-2 alpha / HLA-A2 antibody

The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In humans, this complex is referred to as the human leukocyte antigen (HLA) region. There are 3 major MHC class I proteins encoded by the HLA which are HLA A, HLA B and HLA C.
The HLA A gene is part of the human HLA complex on chromosome 6 and there are a large number of variant alleles of this gene.

General readings

1. Parham, P. and Brodsky, F. M. (1981). Partial purification and some properties of BB7.2. A cytotoxic monoclonal antibody wih specificity for HLA-A2 and a variant of HLA-A28. Hum. Immunol. 3: 277-299.
2. Hogan, K. T. and Brown, S. L.(1992). Localization and characterization of serologic epitopes on HLA-A2. Hum. Immunol. 33: 185-192.
3. Harig, S. et al. (2001) Induction of cytotoxic T-cell responses against immunoglobulin V region-derived
peptides modified at human leukocyte antigen-A2 binding residues. Blood. 98: 2999-3005.
4. Pantenburg, B. et al. (2010) Human CD8(+) T cells clear Cryptosporidium parvum from infected intestinal epithelial cells. Am J Trop Med Hyg. 82:6007.
5. Duncan, L.M. et al. (2010) Stabilization of an E3 ligase-E2-ubiquitin complex increases cell surface MHC class I expression. J Immunol. 184: 6978-85
.6. Wang, B. et al. (2004) Identification of an HLA-A*0201-restricted CD8+ T-cell epitope SSp-1 of SARS-CoV spike protein. Blood. 104: 200-6.
7. Wooldridge, L. et al. (2007) Enhanced immunogenicity of CTL antigens through mutation of the CD8 binding MHC class I invariant region. Eur J Immunol. 37: 1323-33.
8. Wooldridge, L. et al. (2010) MHC class I molecules with Superenhanced CD8 binding properties bypass the requirement for cognate TCR recognition and nonspecifically activate CTLs. J Immunol. 184: 3357-66.
9. Popovic, J. et al. (2011) The only proposed T-cell epitope derived from the TEL-AML1 translocation is not naturally processed. Blood. May 25. [Epub ahead of print].
10. Schmidt, J. et al. (2011) Reversible Major Histocompatibility Complex I-Peptide Multimers Containing Ni2+-Nitrilotriacetic Acid Peptides and Histidine Tags Improve Analysis and Sorting of CD8+ T Cells. J Biol Chem. 286: 41723-35.

6 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

HLA class I A-2 alpha / HLA-A2 antibody

HLA class I A-2 alpha  / HLA-A2 Mouse IgG2b BB7.2 Low Endotoxin Hu C, F, FN, IP
0.5 mg / €550.00
  Acris Antibodies GmbH

HLA class I A-2 alpha / HLA-A2 antibody

Staining of human peripheral blood monocytes with MOUSE ANTI HUMAN HLAA2: FITC (SM1818F). Mouse IgG2b BB7.2 FITC Hu F
0.1 mg / €510.00
  Acris Antibodies GmbH

HLA class I A-2 alpha / HLA-A2 antibody

HLA class I A-2 alpha  / HLA-A2 Mouse IgG2b BB7.2 Purified Hu C, F, IP
0.2 mg / €490.00
  Acris Antibodies GmbH

HLA class I A-2 alpha / HLA-A2 antibody

SM1818R HLA-A2 antibody RPE conjugated staining of Human peripheral blood lymphocytes. Mouse IgG2b BB7.2 PE Hu F
100 Tests / €580.00
  Acris Antibodies GmbH

HLA class I A-2 alpha / HLA-A2 antibody

HLA class I A-2 alpha  / HLA-A2 Mouse IgG2b BB7.2 Hu F
100 reaction / €390.00
  Abnova Taiwan Corp.

HLA class I A-2 alpha / HLA-A2 antibody

Staining of human peripheral blood monocytes with MOUSE ANTI HUMAN HLA-A2:FITC Mouse IgG2b BB7.2 FITC Hu F
50 µg / €350.00
  Novus Biologicals Inc.

6 Item(s)

per page
  • LinkedIn