HLA Class I ABC antibody

Principal name

HLA Class I ABC antibody

Alternative names for HLA Class I ABC antibody

MHC class I ABC, HLA Class 2 ABC, Human Leukocyte antigen class I ABC, Major Histocompatibility complex class I

Available reactivities

Hu (Human), Bov (Bovine), Mky (Monkey), Fe (Feline), Prim (Primate), Chimp (Chimpanzee), Macaque, Bab (Baboon)

Available hosts

Mouse, Rat, Rabbit

Available applications

Immunoprecipitation (IP), Western blot / Immunoblot (WB), Flow Cytometry (F), Enzyme Immunoassay (E), Frozen Sections (C), Functional assay (FN), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of HLA Class I ABC antibody

The antigenic agglomerate major histocompatibility complex (MHC) class I molecules present antigenic peptides to CD8-positive T cells. It is now recognized that the products of the MHC genes are antigen-presenting molecules (APM) designed for the presentation of antigen fragments (peptides) to the T-cell receptor, thus participating in the immune response (1). Recently shown is a mechanism of antigen acquisition for cross-presentation that couples the antigen presentation system of two adjacent cells and is lost in most tumours: gap-junction-mediated intercellular peptide coupling for presentation by bystander MHC class I molecules and transfer to professional antigen presenting cells for cross-priming (2). The mammalian vomeronasal organ detects social information about gender, status, and individuality. It has been shown that small peptides that serve as ligands for major histocompatibility complex (MHC) class I molecules function also as sensory stimuli for a subset of vomeronasal sensory neurons located in the basal Gao- and V2R receptor-expressing zone of the vomeronasal epithelium (3).

General readings

1. Barnstable, C. J. et al. (1978) Production of monoclonal antibodies to group A erythrocytes, HLA and other human cell surface antigens - new tools for genetic analysis. Cell. 14: 9-20..
2. Jacobsen, C. N. et al. (1993) Reactivities of 20 anti-human monoclonal antibodies with leucocytes from ten different animal species. Vet. Immunol. Immunopathol. 39: 461-466.
3. Yoshino, N. et al. (2000) Upgrading of flow cytometric analysis for absolute counts, cytokines and other antigenic molecules of Cynomolgus monkeys (Macaca fascicularis) by using anti-human cross-reactive antibodies. Exp. Anim. 49 (2): 97-110.
4. Stern, P. et al. (1987) Class I-like MHC molecules expressed by baboon placental synctiotrophoblast. J. Immunol. 138 (4): 1088-1091.
5. Verbeek, M. M. et al. (1995) T lymphocyte adhesion to human brain pericytes is mediated via very late antigen-4/vascular cell adhesion molecule-1 interactions.
J. Immunol. 154:5876-5884.
6. Tanabe, M et al. (1992) Structural and functional analysis of monomorphic determinants recognized by monoclonal antibodies reacting with the HLA class I alpha 3 domain. J. Immunol. 148:3203-3209.
7. Ishitani, A. et al. (2003) Protein expression and peptide binding suggest unique and interacting functional roles for HLA-E, F and G in maternal-placental immune recognition. J Immunol. 171: 1376-1384.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

HLA Class I ABC Xenograft marker antibody

Flow Cytometry: Staining of Human peripheral blood lymphocytes with Rat Anti Human HLA ABC antibody (Cat.-No SM2012P) Rat IgG2b YTH862.2 Purified Hu C, F, FN, ICC/IF, IP
0.2 mg / €470.00
  Acris Antibodies GmbH

HLA Class I ABC antibody

Surface staining of human peripheral blood cells with anti-HLA-class I (W6/32) PE. Mouse IgG2a W6/32 FITC Bov, Fe, Hu, Prim F
0.1 mg / €330.00
  Acris Antibodies GmbH

HLA Class I ABC antibody

Staining of human peripheral blood monocytes with MOUSE ANTI HUMAN HLA ABC:BIOTIN (SM1222B). Mouse IgG2a W6/32 Biotin Bov, Fe, Hu, Mky, Prim F
0.1 mg / €430.00
  Acris Antibodies GmbH

HLA Class I ABC antibody

Staining of human peripheral blood lymphocytes with MOUSE ANTI HUMAN HLA ABC:FITC (SM1222F). Mouse IgG2a W6/32 FITC Bov, Fe, Hu, Mky, Prim F
0.1 mg / €390.00
  Acris Antibodies GmbH

HLA Class I ABC antibody

HLA Class I ABC Mouse IgG2a W6/32 HRP Bov, Fe, Hu, Mky, Prim C
0.1 mg / €430.00
  Acris Antibodies GmbH

HLA Class I ABC antibody

Staining of peripheral blood lymphocytes with anti-HLA-ABC - Low Endotoxin (SM1222LE) Mouse IgG2a W6/32 Low Endotoxin Bab, Bov, Chimp, Fe, Hu, Macaque, Mky, Prim C, E, F, FN, ICC/IF, IP
0.5 mg / €550.00
  Acris Antibodies GmbH

HLA Class I ABC antibody

Staining of Human peripheral blood lymphocytes with Mouse anti Human HLA ABC Antibody Cat.-No SM1222P (Clone W6/32) Mouse IgG2a W6/32 Purified Bov, Fe, Hu, Mky, Prim C, E, F, ICC/IF, IP
0.2 mg / €520.00
  Acris Antibodies GmbH

HLA Class I ABC antibody

HLA Class I ABC Mouse IgG2a W6/32 PE Bov, Fe, Hu, Mky, Prim F
100 Tests / €480.00
  Acris Antibodies GmbH

HLA Class I ABC antibody

Surface staining of human peripheral blood cells with anti-HLA-class I (W6/32) PE. Mouse IgG2a W6/32 Biotin Bov, Fe, Hu, Non-Human Primates, Prim F
0.1 mg / €330.00
  Acris Antibodies GmbH

HLA Class I ABC antibody

Surface staining of human peripheral blood cells with anti-HLA-class I (W6/32) PE. Mouse IgG2a W6/32 PE Bov, Fe, Hu, Prim F
0.1 mg / €390.00
  Acris Antibodies GmbH

HLA Class I ABC antibody

HLA Class I ABC Mouse IgG1 MEM-81 Purified Hu F
0.1 mg / €210.00
  Acris Antibodies GmbH

HLA Class I ABC antibody

HLA Class I ABC Mouse IgG1 Bu8 FITC Hu F
0.1 mg / €400.00
  Acris Antibodies GmbH

HLA Class I ABC antibody

HLA Class I ABC Mouse IgG1 Bu8 FITC Hu F
25 µg / €190.00
  Acris Antibodies GmbH

HLA Class I ABC antibody

HLA Class I ABC Mouse IgG1 Bu8 Purified Hu F
0.2 mg / €450.00
  Acris Antibodies GmbH

HLA Class I ABC antibody

HLA Class I ABC Mouse IgG1 Bu8 Purified Hu F
25 µg / €180.00
  Acris Antibodies GmbH

HLA Class I ABC antibody

HLA Class I ABC Mouse IgG1 LY5.1 Purified Hu C
0.5 mg / €430.00
  Acris Antibodies GmbH

HLA Class I ABC antibody

Western blot of human Ramos B cell line lysate (1% laurylmaltoside); non-reduced sample, immunostained by mAb MEM-147 and goat anti-mouse IgG (H+L)-HRP conjugate. Mouse IgG1 MEM-147 Purified Hu F, IP, WB
0.1 mg / €220.00
  Acris Antibodies GmbH

HLA Class I ABC antibody

HLA Class I ABC Mouse IgG3 MEM-123 Purified Bov, Hu, Mky E, F, IP
0.1 mg / €220.00
  Acris Antibodies GmbH

HLA Class I ABC antibody

HLA Class I ABC Mouse IgG1 MEM-147 Hu F, IP, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

HLA Class I ABC antibody

HLA Class I ABC Mouse IgG1 MEM-81 Hu F
0.1 mg / €390.00
  Abnova Taiwan Corp.

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