HLA class I alpha F / HLA-F antibody

Principal name

HLA class I alpha F / HLA-F antibody

Alternative names for HLA class I alpha F / HLA-F antibody

HLA F antigen, Leukocyte antigen F, CDA12, HLA-5.4, HLAF, HLA class I histocompatibility antigen alpha chain F

SwissProt ID

P30511 (Human)

Gene ID

3134 (HLA-F)

Available reactivities

Bov (Bovine), Hu (Human), Ms (Mouse), Por (Porcine)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P)

Background of HLA class I alpha F / HLA-F antibody

HLA-F belongs to the HLA class I heavy chain paralogues. It is a non-classical heavy chain that forms a heterodimer with a beta-2 microglobulin light chain, with the heavy chain anchored in the membrane. Unlike most other HLA heavy chains, this molecule is localized in the endoplasmic reticulum and Golgi apparatus, with a small amount present at the cell surface in some cell types. It contains a divergent peptide-binding groove, and is thought to bind a restricted subset of peptides for immune presentation. This gene belongs to the HLA class I heavy chain paralogues. It encodes a non-classical heavy chain that forms a heterodimer with a beta-2 microglobulin light chain, with the heavy chain anchored in the membrane. Unlike most other HLA heavy chains, this molecule is localized in the endoplasmic reticulum and Golgi apparatus, with a small amount present at the cell surface in some cell types. It contains a divergent peptide-binding groove, and is thought to bind a restricted subset of peptides for immune presentation. This gene exhibits few polymorphisms. Multiple transcript variants encoding different isoforms have been found for this gene. These variants lack a coding exon found in transcripts from other HLA paralogues due to an altered splice acceptor site, resulting in a shorter cytoplasmic domain.

General readings

Burfoot,R.K., (2008) Tissue Antigens 71 (1), 42-50

6 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

HLA class I alpha F / HLA-F antibody

WB Suggested Anti-HLA-F Antibody Titration: 0.2-1 ug/ml; Positive Control: HepG2 cell lysate Rabbit IgG Purified Hu, Por WB
50 µg / €325.00
  OriGene Technologies, Inc.

HLA class I alpha F / HLA-F antibody

WB Suggested Anti-HLA-F Antibody Titration: 0.2-1 ug/ml; Positive Control: 721_B cell lysate; HLA-F is strongly supported by BioGPS gene expression data to be expressed in Human 721_B cells Rabbit IgG Purified Bov, Hu, Por P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

HLA class I alpha F / HLA-F antibody

Human Lung Tissue; Rabbit Anti-HLA-F Antibody . Catalog Number: ARP49411_P050 . Formalin Fixed Paraffin Embedded Tissue: Human Lung Tissue . Observed Staining: Membrane and cytoplasmic in alveolar type I cells . Primary Antibody Concentration: 1:100 . Secondary Antibody: Donkey anti-Rabbit-Cy3 . Secondary Antibody Concentration: 1:200 . Magnification: 20X . Exposure Time: 0.5 - 2.0 sec .; Rabbit Anti-HLA-F Antibody (ARP49411_P050) ) in Human Lung Tissue using Immunohistochemistry Rabbit Aff - Purified Bov, Hu WB
50 µg / €350.00
  AVIVA Systems Biology

HLA class I alpha F / HLA-F antibody

Western Blot: HLA F Antibody [NBP1-59537] - This Anti-HLA-F antibody was used in Western Blot of 721_B tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu WB
50 µg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

HLA class I alpha F / HLA-F (22-305, His-tag)

HLA class I alpha F / HLA-F Human Purified > 90 % by SDS - PAGE E. coli
0.1 mg / €730.00
  Acris Antibodies GmbH

HLA class I alpha F / HLA-F (22-305, His-tag)

HLA class I alpha F / HLA-F Human Purified > 90 % by SDS - PAGE E. coli
20 µg / €300.00
  Acris Antibodies GmbH

6 Item(s)

per page
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