HLA class I B7 alpha / HLA-B antibody

Principal name

HLA class I B7 alpha / HLA-B antibody

Alternative names for HLA class I B7 alpha / HLA-B antibody

HLAB, MHC class I antigen B7, HLA class I histocompatibility antigen, B-7 alpha chain

SwissProt ID

P01889 (Human), Q9TP95 (Human)

Gene ID

3106 (HLA-B)

Available reactivities

Hu (Human)

Available hosts

Mouse, Rabbit

Available applications

Flow Cytometry (F), ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Frozen Sections (C), Paraffin Sections (P)

Background of HLA class I B7 alpha / HLA-B antibody

HLA-B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exon 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-B alleles have been described.

General readings

Parsons, M.S., et al. J. Infect. Dis. 202 SUPPL 3, S356-S360 (2010)
Brockman, M.A., et al. J. Virol. 84(22):11937-11949(2010)
Noble, J.A., et al. Diabetes 59(11):2972-2979(2010)
Lipponen, K., et al. Diabetes (2010) In press
Liao, Y.Q., et al. Zhongguo Shi Yan Xue Ye Xue Za Zhi 18(4):1055-1058(2010)

  1. Quick-Filters:
  2. Highly Validated (1)

15 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

HLA class I B7 alpha / HLA-B (N-term) antibody

  Rabbit polyclonal HLA-B Antibody (N-term)  
Western blot analysis of HLA-B Antibody (N-term) (Cat. #TA325053) in A2058 cell line lysates (35ug/lane). HLA-B (arrow) was detected using the purified Pab. Rabbit Hu WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

HLA class I B7 alpha / HLA-B antibody

  Mouse monoclonal Anti-HLA-B7 Clone BB7.1  
HLA class I B7 alpha / HLA-B Mouse IgG2 BB7.1 Purified Hu F
0.1 mg / €325.00
  OriGene Technologies, Inc.

HLA class I B7 alpha / HLA-B antibody

HLA class I B7 alpha / HLA-B Mouse IgM EP-4 Purified Hu P
0.1 mg / €310.00
  Acris Antibodies GmbH

HLA class I B7 alpha / HLA-B antibody

HLA class I B7 alpha / HLA-B Mouse IgG1 JOAN-1 Purified Hu C, WB
0.1 mg / €310.00
  Acris Antibodies GmbH

HLA class I B7 alpha / HLA-B (Center) antibody

Western blot analysis of HLA-B Antibody (Center) Cat.-No AP52051PU-N in A2058 cell line lysates (35ug/lane).This demonstrates the HLA-B antibody detected the HLA-B protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

HLA class I B7 alpha / HLA-B antibody

Staining of human peripheral blood
lymphocytes with MOUSE ANTI HUMAN HLAB7-FITC (SM1304F) Mouse IgG1 BB7.1 FITC Hu F
0.1 mg / €410.00
  Acris Antibodies GmbH

HLA class I B7 alpha / HLA-B antibody

Staining of human peripheal blood lymphocytes from an HLA-B7 positive donor with mouse anti human HLA-B7 (SM1304P). Mouse IgG1 BB7.1 Purified Hu F
0.2 mg / €520.00
  Acris Antibodies GmbH

HLA class I B7 alpha / HLA-B antibody

HLA class I B7 alpha / HLA-B Mouse IgG1 BB7.1 PE Hu F
100 Tests / €480.00
  Acris Antibodies GmbH

HLA class I B7 alpha / HLA-B antibody

HLA-B MaxPab polyclonal antibody. Western Blot analysis of HLA-B expression in human spleen. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

HLA class I B7 alpha / HLA-B antibody

Western Blot analysis of HLA-B expression in transfected 293T cell line (H00003106-T01) by HLA-B MaxPab polyclonal antibody.

Lane 1: HLA-B transfected lysate(40.50 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

HLA class I B7 alpha / HLA-B antibody

HLA class I B7 alpha / HLA-B Mouse IgG1 JOAN-1 Hu C, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

HLA class I B7 alpha / HLA-B

  Recombinant protein of human major histocompatibility complex, class I, B (HLA-B)  
HLA class I B7 alpha / HLA-B Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

HLA-B 293T Cell Transient Overexpression Lysate(Denatured)

HLA-B 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, HLA (mGFP-tagged) - Human major histocompatibility complex, class I, B (HLA-B), 200 uL, >10^7 TU/mL

Lenti ORF particles, HLA (mGFP-tagged) - Human major histocompatibility complex, class I, B (HLA-B), 200 uL, >10^7 TU/mL  
200 µl / €930.00
  OriGene Technologies, Inc.

Lenti ORF particles, HLA (Myc-DDK tagged) - Human major histocompatibility complex, class I, B (HLA-B) , 200 uL, >10^7 TU/mL

Lenti ORF particles, HLA (Myc-DDK tagged) - Human major histocompatibility complex, class I, B (HLA-B) , 200 uL, >10^7 TU/mL  
200 µl / €830.00
  OriGene Technologies, Inc.

15 Item(s)

per page
  • LinkedIn