HLA class I Cw7 alpha / HLA-C antibody

Principal name

HLA class I Cw7 alpha / HLA-C antibody

Alternative names for HLA class I Cw7 alpha / HLA-C antibody

HLAC, MHC class I antigen Cw7, HLA class I histocompatibility antigen, Cw-7 alpha chain

SwissProt ID

P10321 (Human), Q95603 (Human)

Gene ID

3107 (HLA-C)

Ncbi ID

9606, NP_002108

Available reactivities

Hu (Human)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Immunoprecipitation (IP), Enzyme Immunoassay (E), Paraffin Sections (P)

Background of HLA class I Cw7 alpha / HLA-C antibody

HLA-C belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Over one hundred HLA-C alleles have been described [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

Xu Y., et al. (2009) Tissue Antigens. 74:453-455Zou H.Y., et al. (2009) Tissue Antigens. 74:455-456

7 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

HLA class I Cw7 alpha / HLA-C antibody

Western Blot analysis of HLA-C expression in transfected 293T cell line (H00003107-T01) by HLA-C MaxPab polyclonal antibody.

Lane 1: HLA-C transfected lysate(40.26 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

HLA class I Cw7 alpha / HLA-C antibody

Western Blot analysis of HLA-C expression in transfected 293T cell line (H00003107-T01) by HLA-C MaxPab polyclonal antibody.

Lane 1: HLA-C transfected lysate(40.80 KDa).
Lane 2: Non-transfected lysate. Rabbit Serum Hu E(detection), IP, WB
0.1 ml / €380.00
  Abnova Taiwan Corp.

HLA class I Cw7 alpha / HLA-C antibody

HLA class I Cw7 alpha / HLA-C Rabbit IgG Hu WB
0.1 ml / €340.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

HLA class I Cw7 alpha / HLA-C (25-308, His-tag)

HLA class I Cw7 alpha / HLA-C Human Purified > 90 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

HLA class I Cw7 alpha / HLA-C (25-308, His-tag)

HLA class I Cw7 alpha / HLA-C Human Purified > 90 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

Antibody Pairs

Catalog No.    

HLA-C (Human) IP-WB Antibody Pair

HLA-C (Human) IP-WB Antibody Pair  
1 set / €710.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

HLA-C 293T Cell Transient Overexpression Lysate(Denatured)

HLA-C 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

7 Item(s)

per page
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