HLA class II DM alpha / HLA-DMA antibody

Principal name

HLA class II DM alpha / HLA-DMA antibody

Alternative names for HLA class II DM alpha / HLA-DMA antibody

DMA, RING6, MHC class II antigen DMA, HLA class II histocompatibility antigen, DM alpha chain, Really interesting new gene 6 protein

SwissProt ID

P28067 (Human), P28078 (Mouse)

Gene ID


Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit, Rat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunoprecipitation (IP), Flow Cytometry (F), Frozen Sections (C), Functional assay (FN)

Background of HLA class II DM alpha / HLA-DMA antibody

HLA-DMA belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta chain (DMB), both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

Int J Cancer Suppl. 1994;8:132-3.
Reactivity of lung tumors with lung-derived and non-lung-derived monoclonal antibodies.
Ioachim HL, Pambuccian S, Giancotti F, Dorsett B.
Department of Pathology, Lenox Hill Hospital, New York, NY 10021.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

HLA class II DM alpha / HLA-DMA antibody

  Rabbit Polyclonal Anti-HLA-DMA Antibody  
WB Suggested Anti-HLA-DMA Antibody; Titration: 1.0 ug/ml; Positive Control: MCF7 Whole Cell Rabbit IgG Purified Can, Hu, Rb, Rt WB
50 µg / €360.00
  OriGene Technologies, Inc.

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