HLA class II DP alpha chain / HLA-DPA1 antibody

Principal name

HLA class II DP alpha chain / HLA-DPA1 antibody

Alternative names for HLA class II DP alpha chain / HLA-DPA1 antibody

DP(W3), DP(W4), HLA-SB alpha chain, MHC class II DP3-alpha, MHC class II DPA1, HLA-DP1A, HLASB

SwissProt ID

P04227 (Mouse), P20036 (Human)

Gene ID

3113 (HLA-DPA1)

Available reactivities

Hu (Human), Por (Porcine)

Available hosts

Mouse, Rabbit

Available applications

Radioimmunoassay (R), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), ELISA (detection) (E(detection)), EPair for Elisa (EPair), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F)

Background of HLA class II DP alpha chain / HLA-DPA1 antibody

The specific function of this protein remains unknown.HLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

This product has been used in:Thomas A et al. HLA-D region alpha-chain monoclonal antibodies: cross-reaction between an anti-DP alpha-chain antibody and smooth muscle. J Pathol 154:353-63 (1988). PubMed PMID: 2455029
Adams TE et al. Production and characterization of monoclonal antibodies recognizing the alpha-chain subunits of human ia alloantigens. Immunology 50:613-24 (1983). PubMed PMID: 6197354

15 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

HLA class II DP alpha chain / HLA-DPA1 antibody

Western blot analysis of extracts from Jurkat cells, using HA2Q antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

HLA class II DP alpha chain / HLA-DPA1 antibody

WB Suggested Anti-HLA-DPA1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: Human Thymus Rabbit IgG Purified Hu, Por WB
50 µg / €325.00
  OriGene Technologies, Inc.

HLA class II DP alpha chain / HLA-DPA1 antibody

Human tonsil stained with anti-HLA-DP alpha 1 Antibody Cat.-No AM33239PU (Clone SP228). Rabbit IgG SP228 Purified Hu F, P
0.5 ml / €500.00
  Acris Antibodies GmbH

HLA class II DP alpha chain / HLA-DPA1 antibody

Human tonsil stained with anti-HLA-DP alpha 1 Antibody Cat.-No AM33239PU (Clone SP228). Rabbit IgG SP228 Purified Hu F, P
1 ml / €710.00
  Acris Antibodies GmbH

HLA class II DP alpha chain / HLA-DPA1 antibody

Human tonsil stained with anti-HLA-DP alpha 1 Antibody Cat.-No AM33239PU (Clone SP228). Rabbit IgG SP228 Purified Hu F, P
0.1 ml / €290.00
  Acris Antibodies GmbH

HLA class II DP alpha chain / HLA-DPA1 antibody

HLA-DPA1 MaxPab polyclonal antibody. Western Blot analysis of HLA-DPA1 expression in human spleen. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

HLA class II DP alpha chain / HLA-DPA1 antibody

HLA-DPA1 MaxPab rabbit polyclonal antibody. Western Blot analysis of HLA-DPA1 expression in human kidney. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

HLA class II DP alpha chain / HLA-DPA1 antibody

Western Blot analysis of HLA-DPA1 expression in transfected 293T cell line by HLA-DPA1 monoclonal antibody (M03), clone 1E3.

Lane 1: HLA-DPA1 transfected lysate(29.3 KDa).
Lane 2: Non-transfected lysate. Mouse IgG2a 1E3 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

HLA class II DP alpha chain / HLA-DPA1 antibody

Human Thymus; WB Suggested Anti-HLA-DPA1 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: Human Thymus; HLA-DPA1 antibody - middle region (ARP50199_P050) in Human Thymus cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

HLA class II DP alpha chain / HLA-DPA1 antibody

HLA class II DP alpha chain / HLA-DPA1 Mouse IgG1 TAL 3C3 Purified Hu R, WB
0.1 mg / €340.00
  Novus Biologicals Inc.

HLA class II DP alpha chain / HLA-DPA1 antibody

Western Blot: HLA DPA Antibody [NBP1-59051] - This Anti-HLA-DPA1 antibody was used in Western Blot of Fetal Thymus tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu WB
50 µg / €440.00
  Novus Biologicals Inc.

HLA class II DP alpha chain / HLA-DPA1 antibody

Immunohistochemistry-Paraffin: HLA DPA Antibody [NBP1-89689] Immunohistochemical staining of human lymph node shows strong cytoplasmic positivity in lymphoid cells outside reaction centra. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

HLA class II DP alpha chain / HLA-DPA1

HLA class II DP alpha chain / HLA-DPA1 Human in vitro transl.
2 µg / €300.00
  Abnova Taiwan Corp.

Antibody Pairs

Catalog No.    

HLA-DPA1 (Human) Matched Antibody Pair

HLA-DPA1 (Human) Matched Antibody Pair  
1 set / €710.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

HLA-DPA1 293T Cell Transient Overexpression Lysate(Denatured)

HLA-DPA1 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

15 Item(s)

per page
  • LinkedIn