HLA class II DR alpha / HLA-DRA antibody

Principal name

HLA class II DR alpha / HLA-DRA antibody

Alternative names for HLA class II DR alpha / HLA-DRA antibody

HLA-DRA1, MHC class II antigen DRA, HLA class II histocompatibility antigen DR alpha chain

SwissProt ID

P01903 (Human)

Gene ID

3122 (HLA-DRA)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Mky (Monkey)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB), Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF), ELISA (detection) (E(detection)), Immunoprecipitation (IP), Frozen Sections (C)

Background of HLA class II DR alpha / HLA-DRA antibody

HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

De Gassart A., et al. (2008) Proc. Natl. Acad. Sci. U.S.A. 105:3491-3496
Lapaque N., et al. (2009) J. Biol. Chem. 284:7007-7016

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

HLA class II DR alpha / HLA-DRA antibody

Western blot analysis of extracts of Raji and Jurkat cell lines, using HLA-DRA antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

HLA class II DR alpha / HLA-DRA antibody

Formalin-paraffin human tonsil stained with HLA-DR MAb (Clone LN-3). Mouse IgG2b LN-3 Purified Hu, Mky C, F, ICC/IF, IP, P, WB
0.2 mg / €390.00
  Acris Antibodies GmbH

HLA class II DR alpha / HLA-DRA antibody

Formalin-paraffin human tonsil stained with HLA-DR MAb (Clone LN-3). Mouse IgG2b LN-3 Purified Hu, Mky C, F, ICC/IF, IP, P, WB
0.1 mg / €320.00
  Acris Antibodies GmbH

HLA class II DR alpha / HLA-DRA antibody

Formalin-paraffin human tonsil stained with HLA-DR MAb (Clone LN-3). Mouse IgG2b LN-3 Purified Hu, Mky C, F, ICC/IF, IP, P, WB
20 µg / €160.00
  Acris Antibodies GmbH

HLA class II DR alpha / HLA-DRA antibody

Formalin-paraffin human tonsil stained with HLA-DR MAb (Clone SPM289). Mouse IgG2b SPM289 Purified Hu F, ICC/IF, P, WB
0.2 mg / €390.00
  Acris Antibodies GmbH

HLA class II DR alpha / HLA-DRA antibody

Formalin-paraffin human tonsil stained with HLA-DR MAb (Clone SPM289). Mouse IgG2b SPM289 Purified Hu F, ICC/IF, P, WB
0.1 mg / €320.00
  Acris Antibodies GmbH

HLA class II DR alpha / HLA-DRA antibody

Formalin-paraffin human tonsil stained with HLA-DR MAb (Clone SPM289). Mouse IgG2b SPM289 Purified Hu F, ICC/IF, P, WB
20 µg / €160.00
  Acris Antibodies GmbH

HLA class II DR alpha / HLA-DRA antibody

Staining of normal human peripheral blood cells with 0.125 ug of Purified Mouse IgG2b Isotype Control (open histogram) or 0.125 ug of Anti-Human HLA-DR Purified) (filled histogram) followed by Anti-Mouse IgG FITC .  Cells in the lymphocyte gate were used for analysis. Mouse LN3 Purified Hu F, P
0.1 mg / €120.00
  OriGene Technologies, Inc.

HLA class II DR alpha / HLA-DRA antibody

Predicted band size: 29 kDa . Positive control: Raji cell lysate. Recommended dilution: 1/500-2000. (Gel: 10%SDS-PAGE Lysate: 40 ug Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

HLA class II DR alpha / HLA-DRA (C-term) antibody

Western blot analysis of HLA-DRA Antibody (C-term) (AP17467PU-N) in HL60 cell line lysates (35 µg/lane). HLA-DRA (arrow) was detected using the purified Pab. Rabbit Hu F, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

HLA class II DR alpha / HLA-DRA (N-term) antibody

Western blot analysis of HLA-DRA Antibody (N-term) (AP17468PU-N) in Ramos cell line lysates (35 µg/lane). HLA-DRA (arrow) was detected using the purified Pab. Rabbit Hu F, P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

HLA class II DR alpha / HLA-DRA antibody

HLA-DRA MaxPab polyclonal antibody. Western Blot analysis of HLA-DRA expression in human spleen. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

HLA class II DR alpha / HLA-DRA antibody

HLA-DRA MaxPab polyclonal antibody. Western Blot analysis of HLA-DRA expression in human spleen. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

HLA class II DR alpha / HLA-DRA antibody

HLA-DRA MaxPab polyclonal antibody. Western Blot analysis of HLA-DRA expression in human spleen. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

HLA class II DR alpha / HLA-DRA antibody

HLA-DRA MaxPab rabbit polyclonal antibody. Western Blot analysis of HLA-DRA expression in A-431. Rabbit Serum Hu E(detection), IP, WB
0.1 ml / €380.00
  Abnova Taiwan Corp.

HLA class II DR alpha / HLA-DRA antibody

Western Blot analysis of HLA-DRA expression in transfected 293T cell line (H00003122-T03) by HLA-DRA MaxPab polyclonal antibody.

Lane 1: HLA-DRA transfected lysate(28.60 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

HLA class II DR alpha / HLA-DRA antibody

Flow cytometric analysis of human peripheral blood lymphocytes using Anti-HLA-DR Antibody-FITC labled. Mouse IgG1 FITC Hu F, ICC/IF
50 Assays / €250.00
  Cohesion Biosciences Ltd.

HLA class II DR alpha / HLA-DRA antibody

Flow cytometric analysis of human peripheral blood lymphocytes using Anti-HLA-DR Antibody-FITC labled. Mouse IgG1 FITC Hu F, ICC/IF
100 Assays / €330.00
  Cohesion Biosciences Ltd.

HLA class II DR alpha / HLA-DRA antibody

Flow cytometric analysis of human peripheral blood lymphocytes using Anti-HLA-DR Antibody-PE labled. Mouse IgG1 PE Hu F, ICC/IF
50 Assays / €280.00
  Cohesion Biosciences Ltd.

HLA class II DR alpha / HLA-DRA antibody

Flow cytometric analysis of human peripheral blood lymphocytes using Anti-HLA-DR Antibody-PE labled. Mouse IgG1 PE Hu F, ICC/IF
100 Assays / €420.00
  Cohesion Biosciences Ltd.

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