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HLA class II DR beta 3 / HLA-DRB3 antibody

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Principal name

HLA class II DR beta 3 / HLA-DRB3 antibody

Alternative names for HLA class II DR beta 3 / HLA-DRB3 antibody

MHC class II antigen DRB3, HLA class II histocompatibility antigen DRB3-1 beta chain

SwissProt ID

P79483 (Human)

Gene ID

3125 (HLA-DRB3)

Ncbi ID

9606, NP_072049, AAH08987, NM_022555, NP_072049.2

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of HLA class II DR beta 3 / HLA-DRB3 antibody

HLA-DRB3 belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DRA) and a beta (DRB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. DRB1 is expressed at a level five times higher than its paralogues DRB3, DRB4 and DRB5. The presence of DRB3 is linked with allelic variants of DRB1, otherwise it is omitted. There are 4 related pseudogenes: DRB2, DRB6, DRB7, DRB8 and DRB9. [provided by RefSeq, Jul 2008]

H00003125-B02 - HLA class II DR beta 3 / HLA-DRB3
Western Blot analysis of HLA-DRB3 expression in transfected 293T cell line (H00003125-T01) by HLA-DRB3 MaxPab polyclonal antibody.Lane 1: HLA-DRB3 transfected lysate(29.26 KDa).Lane 2: Non-transfected lysate.
H00003125-B02 - HLA class II DR beta 3 / HLA-DRB3
HLA-DRB3 MaxPab polyclonal antibody. Western Blot analysis of HLA-DRB3 expression in human liver.
H00003125-B02 - HLA class II DR beta 3 / HLA-DRB3
FACS analysis of negative control 293 cells (Black) and HLA-DRB3 expressing 293 cells (Green) using HLA-DRB3 purified MaxPab mouse polyclonal antibody.
H00003125-B01 - HLA class II DR beta 3 / HLA-DRB3
Western Blot analysis of HLA-DRB3 expression in transfected 293T cell line (H00003125-T03) by HLA-DRB3 MaxPab polyclonal antibody.Lane 1: HLA-DRB3 transfected lysate(29.37 KDa).Lane 2: Non-transfected lysate.
H00003125-B02P - HLA class II DR beta 3 / HLA-DRB3
Western Blot analysis of HLA-DRB3 expression in transfected 293T cell line (H00003125-T01) by HLA-DRB3 MaxPab polyclonal antibody.Lane 1: HLA-DRB3 transfected lysate(29.26 KDa).Lane 2: Non-transfected lysate.
H00003125-B02P - HLA class II DR beta 3 / HLA-DRB3
HLA-DRB3 MaxPab polyclonal antibody. Western Blot analysis of HLA-DRB3 expression in human liver.
H00003125-B02P - HLA class II DR beta 3 / HLA-DRB3
FACS analysis of negative control 293 cells (Black) and HLA-DRB3 expressing 293 cells (Green) using HLA-DRB3 purified MaxPab mouse polyclonal antibody.
H00003125-D01P - HLA class II DR beta 3 / HLA-DRB3
HLA-DRB3 MaxPab rabbit polyclonal antibody. Western Blot analysis of HLA-DRB3 expression in human kidney.
H00003125-D01P - HLA class II DR beta 3 / HLA-DRB3
Western Blot analysis of HLA-DRB3 expression in transfected 293T cell line (H00003125-T01) by HLA-DRB3 MaxPab polyclonal antibody.Lane 1: HLA-DRB3 transfected lysate(30.00 KDa).Lane 2: Non-transfected lysate.
GTX105068 - HLA class II DR beta 3 / HLA-DRB3
Immunofluorescence analysis of methanol-fixed A549, using HLA-DRB3(GTX105068) antibody at 1:500 dilution.
NBP1-33666 - HLA class II DR beta 3 / HLA-DRB3
Western Blot: HLA DRB3 Antibody [NBP1-33666] – Western blot analysis of HLA DRB3 on A549 lysates using NBP1-33666 at a dilution of 1:1000. 30ug whole cell lysate loaded on 12% SDS PAGE gel.
GTX119428 - HLA class II DR beta 3 / HLA-DRB3
Immunohistochemical analysis of paraffin-embedded gastric ca, using HLA-DRB3(GTX119428) antibody at 1:500 dilution.
GTX119428 - HLA class II DR beta 3 / HLA-DRB3
Immunofluorescence analysis of methanol-fixed HeLa, using HLA-DRB3(GTX119428) antibody at 1:500 dilution.

3 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

HLA class II DR beta 3 / HLA-DRB3 antibody
  Rabbit polyclonal antibody to HLA-DRB3 (major histocompatibility complex, class II, DR beta 3)  
Immunofluorescence analysis of methanol-fixed A549, using HLA-DRB3(TA308897) antibody at 1:500 dilution. Rabbit IgG Aff - Purified Hu ICC/IF
0.1 ml / €416.00
  OriGene Technologies, Inc.

HLA class II DR beta 3 / HLA-DRB3 antibody
  HLA-DRB3 Rabbit Polyclonal Antibody  
Western blot analysis of extracts of HepG2 cell lines, using HLA-DRB3 antibody. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €335.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

HLA overexpression lysate
HLA overexpression lysate  
0.1 mg / €295.00
  OriGene Technologies, Inc.

3 Item(s)

per page

Available Filters

Product Type
  1. Lysate (1)
  2. Primary Antibody (2)
Clonality
  1. Polyclonal (2)
Target
  1. HLA class II DR beta 3 / HLA-DRB3 (2)
Reactivity
  1. Human (Hu) (2)
  2. Mouse (Ms) (1)
  3. Rat (Rt) (1)
Applications
  1. Immunocytochemistry/​Immunofluorescence (ICC/IF) (1)
  2. Western blot / Immunoblot (WB) (1)
Presentation
  1. Aff - Purified (1)
  2. Purified (1)
Host
  1. Rabbit (2)
Images
  1. 1 image (2)
Images: Applications
  1. Immunofluorescence (IF) (1)
  2. Western blot / Immunoblot (WB) (1)
Manufacturer
  1. OriGene Technologies (3)
Service
 
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