HLA class II DR beta 3 / HLA-DRB3 antibody

Principal name

HLA class II DR beta 3 / HLA-DRB3 antibody

Alternative names for HLA class II DR beta 3 / HLA-DRB3 antibody

MHC class II antigen DRB3, HLA class II histocompatibility antigen DRB3-1 beta chain

SwissProt ID

P79483 (Human)

Gene ID

3125 (HLA-DRB3)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of HLA class II DR beta 3 / HLA-DRB3 antibody

HLA-DRB3 belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DRA) and a beta (DRB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. DRB1 is expressed at a level five times higher than its paralogues DRB3, DRB4 and DRB5. The presence of DRB3 is linked with allelic variants of DRB1, otherwise it is omitted. There are 4 related pseudogenes: DRB2, DRB6, DRB7, DRB8 and DRB9. [provided by RefSeq, Jul 2008]

12 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

HLA class II DR beta 3 / HLA-DRB3 antibody

Immunofluorescence analysis of methanol-fixed A549, using HLA-DRB3(TA308897) antibody at 1:500 dilution. Rabbit IgG Aff - Purified Hu ICC/IF
0.1 ml / €325.00
  OriGene Technologies, Inc.

HLA class II DR beta 3 / HLA-DRB3 antibody

Western blot analysis of extracts of HepG2 cell lines, using HLA-DRB3 antibody. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

HLA class II DR beta 3 / HLA-DRB3 antibody

Western Blot analysis of HLA-DRB3 expression in transfected 293T cell line (H00003125-T03) by HLA-DRB3 MaxPab polyclonal antibody.

Lane 1: HLA-DRB3 transfected lysate(29.37 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

HLA class II DR beta 3 / HLA-DRB3 antibody

HLA class II DR beta 3 / HLA-DRB3 Mouse Hu WB
50 µg / €370.00
  Abnova Taiwan Corp.

HLA class II DR beta 3 / HLA-DRB3 antibody

Western Blot analysis of HLA-DRB3 expression in transfected 293T cell line (H00003125-T01) by HLA-DRB3 MaxPab polyclonal antibody.

Lane 1: HLA-DRB3 transfected lysate(29.26 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), F, WB
50 µl / €370.00
  Abnova Taiwan Corp.

HLA class II DR beta 3 / HLA-DRB3 antibody

Western Blot analysis of HLA-DRB3 expression in transfected 293T cell line (H00003125-T01) by HLA-DRB3 MaxPab polyclonal antibody.

Lane 1: HLA-DRB3 transfected lysate(29.26 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), F, WB
50 µg / €370.00
  Abnova Taiwan Corp.

HLA class II DR beta 3 / HLA-DRB3 antibody

HLA-DRB3 MaxPab rabbit polyclonal antibody. Western Blot analysis of HLA-DRB3 expression in human kidney. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

HLA class II DR beta 3 / HLA-DRB3 antibody

Western  Blot:  HLA DRB3 Antibody [NBP1-33666] – Western blot analysis of HLA DRB3 on A549 lysates using NBP1-33666 at a dilution of 1:1000. 30ug whole cell lysate loaded on 12% SDS PAGE gel. Rabbit IgG Hu ICC/IF, WB
0.1 mg / €420.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

HLA class II DR beta 3 / HLA-DRB3

HLA class II DR beta 3 / HLA-DRB3 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

HLA class II DR beta 3 / HLA-DRB3

HLA class II DR beta 3 / HLA-DRB3 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

HLA-DRB3 293T Cell Transient Overexpression Lysate(Denatured)

HLA-DRB3 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

HLA overexpression lysate

HLA overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

12 Item(s)

per page
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