HLA Class II DR beta 4 / HLA-DRB4 antibody

Principal name

HLA Class II DR beta 4 / HLA-DRB4 antibody

Alternative names for HLA Class II DR beta 4 / HLA-DRB4 antibody

MHC class II antigen DRB4, HLA class II histocompatibility antigen DR beta 4 chain

SwissProt ID

P06343 (Mouse), P13762 (Human)

Gene ID

3126 (HLA-DRB4)

Available reactivities

Hu (Human)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection))

Background of HLA Class II DR beta 4 / HLA-DRB4 antibody

HLA-DRB4 belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DRA) and a beta (DRB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. DRB1 is expressed at a level five times higher than its paralogues DRB3, DRB4 and DRB5. The presence of DRB4 is linked with allelic variants of DRB1, otherwise it is omitted. There are 4 related pseudogenes: DRB2, DRB6, DRB7, DRB8 and DRB9. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

8 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

HLA Class II DR beta 4 / HLA-DRB4 antibody

Sample(30 ug whole cell lysate). A:Raji . 12% SDS PAGE. TA308898 diluted at 1:1000 Rabbit IgG Aff - Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

HLA Class II DR beta 4 / HLA-DRB4 antibody

Western Blot analysis of HLA-DRB4 expression in transfected 293T cell line (H00003126-T01) by HLA-DRB4 MaxPab polyclonal antibody.

Lane 1: HLA-DRB4 transfected lysate(29.90 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

HLA Class II DR beta 4 / HLA-DRB4 antibody

Immunoperoxidase of monoclonal antibody to HLA-DRB4 on formalin-fixed paraffin-embedded human tonsil. [antibody concentration 1 ug/ml] Mouse IgG2b 4C8 Purified Hu E, P, WB
50 µg / €370.00
  Abnova Taiwan Corp.

HLA Class II DR beta 4 / HLA-DRB4 antibody

HLA Class II DR beta 4 / HLA-DRB4 Mouse IgG2b 4C8 Ascites Hu E, WB
0.2 ml / €370.00
  Abnova Taiwan Corp.

HLA Class II DR beta 4 / HLA-DRB4 antibody

Western Blot: HLA DRB4 Antibody [NBP1-32553] - (30 ug whole cell lysate) A:Raji  12% SDS PAGE diluted at 1:1000 Rabbit IgG Hu WB
0.1 mg / €420.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

HLA Class II DR beta 4 / HLA-DRB4

HLA Class II DR beta 4 / HLA-DRB4 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

HLA Class II DR beta 4 / HLA-DRB4

HLA Class II DR beta 4 / HLA-DRB4 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

HLA Class II DR beta 4 / HLA-DRB4

HLA Class II DR beta 4 / HLA-DRB4 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

8 Item(s)

per page
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