HMGB4 antibody

Principal name

HMGB4 antibody

Alternative names for HMGB4 antibody

High mobility group protein B4

SwissProt ID

Q32L34 (Bovin), Q6P8W9 (Mouse), Q8WW32 (Human)

Gene ID

127540

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Enzyme Immunoassay (E), Paraffin Sections (P)

Background of HMGB4 antibody

High mobility group protein B4?is a?transcription factor?that in humans is encoded by the?HMGB4?gene.HMGB4 is strongly and preferentially expressed in the adult mouse testis and weakly in the brain; but not in many other tissues. HMGB4 associates with chromatin; and in transfection assays; in contrast to HMGB1; it acts as a potent transcriptiol repressor. During spermatogenesis; HMGB4 is present in the euchromatin of late pachytene spermatocytes and haploid round spermatids; whereas stronger expression is observed during the elongation phase; where it localizes to the basal pole of the nucleus in a manner mutually exclusive with H1FNT (H1T2) localized at the apical pole. HMGB4 basal localization is lost in H1FNT-mutant spermatids; showing that H1FNT provides a positiol cue for organizing chromatin domains within the nucleus. These results show that HMGB4 and H1FNT specify distinct chromatin domains at the apical and basal poles of the elongating spermatid nucleus.

General readings

Gerhard,D.S., Genome Res. 14 (10B), 2121-2127 (2004)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

HMGB4 antibody

Immunohistochemical staining of paraffin-embedded Human liver tissue within the normal limits using anti-HMGB4 mouse monoclonal antibody.(Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120°C for 3 min, TA808611)(1:150) Mouse IgG1 OTI5G3 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

HMGB4 antibody

Predicted band size: 22 kDa . Positive control: 231 cell and human fetal liver tissue lysate. Recommended dilution: 1/200-1000. (Gel: 12%SDS-PAGE Lane1: 231 cell lysate Lane2: Human fetal liver tissue lysate Lysates: 40 ug per lane Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 2 minutes) Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

HMGB4 antibody

WB Suggested Anti-HMGB4 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: HT1080 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

HMGB4 antibody

WB Suggested Anti-HMGB4 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: Jurkat cell lysate Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

HMGB4 (N-term) antibody

Western blot analysis of rat testicle tissue lysis using HMGB4 antibody Rabbit IgG Aff - Purified Hu, Ms, Rt ICC/IF, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

HMGB4 antibody

Western blot analysis of rat testis tissue lysate. Using HMGB4 polyclonal antibody ( Cat # PAB7982 ) . Rabbit Hu, Ms, Rt WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

HMGB4 antibody

Human HT1080; WB Suggested Anti-HMGB4 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: HT1080 cell lysate; HMGB4 antibody - N-terminal region (ARP39851_P050) in Human HT1080 cells using Western Blot Rabbit Aff - Purified Bov, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

HMGB4 antibody

Human Jurkat; WB Suggested Anti-HMGB4 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: Jurkat cell lysate; HMGB4 antibody - C-terminal region (ARP39852_P050) in Human Jurkat cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

HMGB4 antibody

HMGB4 Rabbit IgG Aff - Purified Hu, Ms, Rt WB
0.1 mg / €290.00
  Boster Immunoleader

HMGB4 antibody

HMGB4 Rabbit IgG Hu, Ms, Rt WB
0.1 mg / €400.00
  Novus Biologicals Inc.

Lysates

Catalog No.    

HMGB4 overexpression lysate

HMGB4 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

HMGB4 overexpression lysate

HMGB4 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

12 Item(s)

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