HNF1 alpha / TCF1 antibody

Principal name

HNF1 alpha / TCF1 antibody

Alternative names for HNF1 alpha / TCF1 antibody

HNF1A, LFB1, LF-B1, TCF-1, Transcription factor 1, Hepatocyte nuclear factor 1-alpha, Liver-specific transcription factor LF-B1

SwissProt ID

P15257 (Rat), P20823 (Human), P22361 (Mouse), Q90867 (Chick)

Gene ID

6927 (HNF1A), 24817 (Hnf1a)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Chk (Chicken), Por (Porcine), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Ze (Zebrafish)

Available hosts

Rabbit, Mouse, Goat

Available applications

Paraffin Sections (P), Western blot / Immunoblot (WB), Frozen Sections (C), Enzyme Immunoassay (E)

Background of HNF1 alpha / TCF1 antibody

T-cell factor-1 (TCF-1) is a DNA-binding transcriptional activator that isessential for lymphoid cell development. The TCF family of transcription factors are activated by the Wnt-1 and Wingless pathways and are characterized by the presence of a conserved protein motif, the high mobility group (HMG) 1 box, which mediates DNA binding. Several alternative splice variants of TCF-1 have been identified, including TCF-1A, which share a conserved amino terminus and differ in the carboxy terminal sequences. The Wnt mediated signaling pathway induces cytosolic β-catenin binding to TCF proteins within the nucleus, leading to the enhanced expression of the Wnt target genes. The β-catenin-TCF complexes are negatively regulated by the adenomatous polyposis coli (APC) tumor suppressor protein, which phosphorylates β-catenin and, in turn, increases the degradation of cytosolic β-catenin and inhibits the transcriptional activity of the TCF proteins. Mutations in the APC gene, which are commonly observed in colorectal carcinomas, disrupt this regulatory pathway and correlate with an accumulation of β-catenin and the increased activation of the TCF target genes.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

HNF1 alpha / TCF1 antibody

Figure 1. Western blot analysis using AM05273PU-N antibody at 1 µg/ml on Jurkat cell lysates. Mouse IgG 7H3 Purified Hu C, WB
0.1 mg / €550.00
  Acris Antibodies GmbH

HNF1 alpha / TCF1 antibody

  Rabbit Polyclonal Anti-HNF1A  
WB Suggested Anti-HNF1A Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: OVCAR-3 cell lysate HNF1A is supported by BioGPS gene expression data to be expressed in OVCAR3 Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rt P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

HNF1 alpha / TCF1 antibody

  Rabbit polyclonal antibody to HNF-1 alpha (HNF1 homeobox A)  
HNF1 alpha antibody [N1N3] detects HNF1 alpha protein by Western blot analysis. A. 30 ug HepG2 whole cell lysate/extract. 7.5 % SDS-PAGE. HNF1 alpha antibody [N1N3] (TA308567) dilution: 1:5000 Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

HNF1 alpha / TCF1 antibody

  Anti-HNF1A Rabbit Polyclonal Antibody  
Western blot analysis of Human liver cancer tissue using TA321150 (HNF1A Antibody) at dilution 1/150 Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

HNF1 alpha / TCF1 antibody

  Anti-HNF1A Rabbit Polyclonal Antibody  
Western blot analysis of Human liver cancer tissue using TA321151(HNF1A Antibody) at dilution 1/150 Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

HNF1 alpha / TCF1 antibody

  Anti-HNF1A Rabbit Polyclonal Antibody  
Predicted band size: 56 kDa . Positive control: Mouse liver tissue lysate. Recommended dilution: 1/500-2000. (Gel: 10%SDS-PAGE Lysate: 40 ug per lane Primary antibody: 1/400 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 45 seconds) Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

HNF1 alpha / TCF1 antibody

  Rabbit polyclonal HNF1A Antibody (Center)  
Western blot analysis of HNF1A Antibody (Center) (Cat. #TA325066) in mouse liver tissue lysates (35ug/lane). HNF1A (arrow) was detected using the purified Pab. Rabbit Hu, Ms WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

HNF1 alpha / TCF1 antibody

  Rabbit Polyclonal anti-HNF1A Antibody  
Host: Rabbit; Target Name: HNF1A; Sample Tissue: 293T Whole Cell lysates; Antibody Dilution: 1.0ug/ml Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

HNF1 alpha / TCF1 antibody

  Rabbit Polyclonal Anti-HNF1A Antibody - N-terminal region  
HNF1 alpha / TCF1 Rabbit IgG Purified Bov, Can, Eq, Hu, Ms, Por, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

HNF1 alpha / TCF1 antibody

Western blot (WB) analysis of TCF-1 antibody (Cat.-No.: AP06685PU-N) in extracts from HUVEC cells. Rabbit Aff - Purified Hu, Ms P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

HNF1A - human gene knockout kit via CRISPR

HNF1A - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

HNF1A - human gene knockout kit via CRISPR

HNF1A - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

HNF1A - human gene knockout kit via CRISPR

HNF1A - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

HNF1A - human gene knockout kit via CRISPR

HNF1A - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

HNF1 alpha / TCF1

  Recombinant protein of human HNF1 homeobox A (HNF1A)  
HNF1 alpha / TCF1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, HNF1A (mGFP-tagged) - Human HNF1 homeobox A (HNF1A), 200 uL, >10^7 TU/mL

Lenti ORF particles, HNF1A (mGFP-tagged) - Human HNF1 homeobox A (HNF1A), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, HNF1A (Myc-DDK tagged) - Human HNF1 homeobox A (HNF1A) , 200 uL, >10^7 TU/mL

Lenti ORF particles, HNF1A (Myc-DDK tagged) - Human HNF1 homeobox A (HNF1A) , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Hnf1a (GFP-tagged ORF) - Rat HNF1 homeobox A (Hnf1a), 200 uL, >10^7 TU/mL

Lenti ORF particles, Hnf1a (GFP-tagged ORF) - Rat HNF1 homeobox A (Hnf1a), 200 uL, >10^7 TU/mL  
200 µl / €1,290.00
  OriGene Technologies, Inc.

Lenti ORF particles, Hnf1a (Myc-DDK-tagged ORF) - Rat HNF1 homeobox A (Hnf1a), 200 uL, >10^7 TU/mL

Lenti ORF particles, Hnf1a (Myc-DDK-tagged ORF) - Rat HNF1 homeobox A (Hnf1a), 200 uL, >10^7 TU/mL  
200 µl / €1,155.00
  OriGene Technologies, Inc.

19 Item(s)

per page
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