hnRNP core protein A1 / HNRNPA1 antibody

Principal name

hnRNP core protein A1 / HNRNPA1 antibody

Alternative names for hnRNP core protein A1 / HNRNPA1 antibody

HNRPA1, Heterogeneous nuclear ribonucleoprotein A1, hnRNP-A1, Helix-destabilizing protein, Single-strand RNA-binding protein

SwissProt ID

P04256 (Rat), P09651 (Human), P09867 (Bovin), P17130 (Xenla), P49312 (Mouse)

Gene ID

3178 (HNRNPA1), 15382 (Hnrnpa1), 29578

Available reactivities

Bov (Bovine), Can (Canine), Chk (Chicken), Hu (Human), Ms (Mouse), Por (Porcine), Rt (Rat), African clawed frog, Mky (Monkey), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), ELISA (detection) (E(detection))

Background of hnRNP core protein A1 / HNRNPA1 antibody

HNRPA1 belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). HNRPA1 has two repeats of quasi-RRM domains that bind to RNAs. It is one of the most abundant core proteins of hnRNP complexes and it is localized to the nucleoplasm. HNRPA1 is involved in the packaging of pre-mRNA into hnRNP particles, transport of poly A+ mRNA from the nucleus to the cytoplasm, and may modulate splice site selection. It is also thought have a primary role in the formation of specific myometrial protein species in parturition. This gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It is one of the most abundant core proteins of hnRNP complexes and it is localized to the nucleoplasm. This protein, along with other hnRNP proteins, is exported from the nucleus, probably bound to mRNA, and is immediately re-imported. Its M9 domain acts as both a nuclear localization and nuclear export signal. The encoded protein is involved in the packaging of pre-mRNA into hnRNP particles, transport of poly A+ mRNA from the nucleus to the cytoplasm, and may modulate splice site selection. It is also thought have a primary role in the formation of specific myometrial protein species in parturition. Multiple alternatively spliced transcript variants have been found for this gene but only two transcripts are fully described. These variants have multiple alternative transcription initiation sites and multiple polyA sites.

General readings

Kim C.S., et al. (2007) J. Virol. 81:3852-3865Biamonti G., et al. (1989) J. Mol. Biol. 207:491-503

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

hnRNP core protein A1 / HNRNPA1 antibody

  Rabbit Polyclonal Anti-HNRPA1 Antibody  
WB Suggested Anti-HNRPA1 Antibody Titration: 1.25 ug/ml; ELISA Titer: 1: 312500; Positive Control: Jurkat cell lysate; HNRNPA1 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

hnRNP core protein A1 / HNRNPA1 antibody

  Rabbit polyclonal anti-hnRNP A1 antibody  
Western blot analysis of extracts from 293 cells, Jurkat cells and COLO205 cells, using hnRNP A1 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

hnRNP core protein A1 / HNRNPA1 antibody

  Anti-HNRNPA1 Rabbit Polyclonal Antibody  
Predicted band size: 39 kDa . Positive control: 293 cells lysate. Recommended dilution: 1/ 500-1000. (Gel: 10%SDS-PAGE Lysate: 30 ug Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

hnRNP core protein A1 / HNRNPA1 antibody

  Rabbit Polyclonal Anti-HNRPA1 Antibody  
WB Suggested Anti-HNRPA1 Antibody Titration: 1.25 ug/ml; ELISA Titer: 1: 1562500; Positive Control: Jurkat cell lysate; HNRNPA1 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

hnRNP core protein A1 / HNRNPA1 antibody

Immunohistochemistry analyzes of hnRNP A1 antibody (Cat.-No.: AP20408PU-N) in paraffin-embedded human liver carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

hnRNP core protein A1 / HNRNPA1 antibody

Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit IgG Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

hnRNP core protein A1 / HNRNPA1 antibody

Immunohistochemistry analysis of paraffin-embedded human liver carcinoma tissue, using hnRNP A1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
50 µg / €230.00
  Assay Biotech

hnRNP core protein A1 / HNRNPA1 antibody

Immunohistochemistry analysis of paraffin-embedded human liver carcinoma tissue, using hnRNP A1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

Hnrnpa1 - mouse gene knockout kit via CRISPR

Hnrnpa1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Hnrnpa1 - mouse gene knockout kit via CRISPR

Hnrnpa1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Hnrnpa1 - mouse gene knockout kit via CRISPR

Hnrnpa1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Hnrnpa1 - mouse gene knockout kit via CRISPR

Hnrnpa1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

hnRNP core protein A1 / HNRNPA1 (transcript variant 1)

  Recombinant protein of human heterogeneous nuclear ribonucleoprotein A1 (HNRNPA1), transcript variant 1  
hnRNP core protein A1 / HNRNPA1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

hnRNP core protein A1 / HNRNPA1 (transcript variant 2)

  Recombinant protein of human heterogeneous nuclear ribonucleoprotein A1 (HNRNPA1), transcript variant 2  
hnRNP core protein A1 / HNRNPA1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

hnRNP core protein A1 / HNRNPA1 (1-320, His-tag)

hnRNP core protein A1 / HNRNPA1 Human Purified > 85 % by SDS - PAGE E. coli
0.5 mg / €940.00
  Acris Antibodies GmbH

hnRNP core protein A1 / HNRNPA1 (1-320, His-tag)

hnRNP core protein A1 / HNRNPA1 Human Purified > 85 % by SDS - PAGE E. coli
0.1 mg / €370.00
  Acris Antibodies GmbH

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, HNRNPA1 (mGFP-tagged) - Human heterogeneous nuclear ribonucleoprotein A1 (HNRNPA1), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, HNRNPA1 (mGFP-tagged) - Human heterogeneous nuclear ribonucleoprotein A1 (HNRNPA1), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €960.00
  OriGene Technologies, Inc.

Lenti ORF particles, HNRNPA1 (mGFP-tagged) - Human heterogeneous nuclear ribonucleoprotein A1 (HNRNPA1), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, HNRNPA1 (mGFP-tagged) - Human heterogeneous nuclear ribonucleoprotein A1 (HNRNPA1), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €950.00
  OriGene Technologies, Inc.

Lenti ORF particles, HNRNPA1 (Myc-DDK tagged) - Human heterogeneous nuclear ribonucleoprotein A1 (HNRNPA1), transcript variant 1 , 200 uL, >10^7 TU/mL

Lenti ORF particles, HNRNPA1 (Myc-DDK tagged) - Human heterogeneous nuclear ribonucleoprotein A1 (HNRNPA1), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €860.00
  OriGene Technologies, Inc.

Lenti ORF particles, HNRNPA1 (Myc-DDK tagged) - Human heterogeneous nuclear ribonucleoprotein A1 (HNRNPA1), transcript variant 2 , 200 uL, >10^7 TU/mL

Lenti ORF particles, HNRNPA1 (Myc-DDK tagged) - Human heterogeneous nuclear ribonucleoprotein A1 (HNRNPA1), transcript variant 2 , 200 uL, >10^7 TU/mL  
200 µl / €850.00
  OriGene Technologies, Inc.

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