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HOXA4 / HOX1D antibody

Principal name

HOXA4 / HOX1D antibody

Alternative names for HOXA4 / HOX1D antibody

Homeobox protein Hox-A4, Hox-1D, Hox-1.4

SwissProt ID

P06798 (Mouse), P09635 (Rat), P17277 (Chick), Q00056 (Human), Q28598 (Sheep)

Gene ID

3201 (HOXA4)

Ncbi ID

9606, NP_002132.3, AAI60036.1, NM_002141

Available reactivities

Hu (Human), Rt (Rat), Ms (Mouse), Can (Canine)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of HOXA4 / HOX1D antibody

The Hox homeobox genes encode proteins that are transcriptional regulators with an established role in embryonic development. HoxA4 (homeobox A4), also known as HOX1D or HOX1, is a 320 amino acid protein that localizes to the nucleus and contains one homeobox DNA-binding domain. Expressed in the embryonic nervous system, HoxA4 functions as a sequence-specific DNA-binding transcription factor that is part of a regulatory mechanism that provides cells with positional identities during development. Via its ability to bind DNA, HoxA4 plays an important role in the regulation of gene expression, as well as morphogenesis and differentiation. The gene encoding HoxA4 maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Defects in some of the genes localized to chromosome 7 have been linked to osteogenesis imperfecta, Williams-Beuren syndrome, Pendred syndrome, lissencephaly, citrullinemia and Shwachman-Diamond syndrome.

General readings

1. Klausen C, Leung PC, Auersperg N, Cell motility and spreading are suppressed by HOXA4 in ovarian cancer cells: possible involvement of beta1 integrin. Molecular cancer research : MCR 2009 Sep 7 (9): 1425-37.
PMID: 19723874

HOXA4 polyclonal antibody (A01), Lot # 061025JCS1 Western Blot analysis of HOXA4 expression in PC-12 ( Cat # L012V1 ).

H00003201-A01

ELISA: HOXA4 Antibody

TA590708

(0.1ug/ml) staining of Human Colon lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

TA311222

Predicted cell location: Cytoplasm, Nucleus. Positive control: Human liver and colon cancer tissue. Recommended dilution: 1/25-100 The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA323052 (HOXA4 Antibody) at dilution 1/20, on the right is treated with the synthetic peptide. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using TA323052 (HOXA4 Antibody) at dilution 1/20, on the right is treated with the synthetic peptide. (Original magnification: ×200)

TA323052

TA323052

Primary Antibodies

Catalog No.	Host	Iso.	Pres.	React.	Applications
TA311222	HOXA4 / HOX1D antibody
	Goat Anti-HOXA4 Antibody
	Goat		Aff - Purified	Can, Hu	E, WB	0.1 mg / €360.00
						OriGene Technologies, Inc.
TA323052	HOXA4 / HOX1D antibody
	Anti-HOXA4 Rabbit Polyclonal Antibody
	Rabbit	IgG	Purified	Hu, Ms, Rt	E, P	0.1 ml / €335.00
						OriGene Technologies, Inc.
+1 additional image

Lysates

Catalog No.
LY419504	HOXA4 overexpression lysate
		0.1 mg / €295.00
		OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.
RC213447L2V	Lenti ORF particles, HOXA4 (mGFP-tagged)-Human homeobox A4 (HOXA4), 200 uL, >10^7 TU/mL
		200 µl / €989.00
		OriGene Technologies, Inc.

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