HOXB13 antibody

Principal name

HOXB13 antibody

Alternative names for HOXB13 antibody

Homeobox protein Hox-B13

SwissProt ID

P70321 (Mouse), Q92826 (Human)

Gene ID

15408 (Hoxb13), 10481 (HOXB13), 3104813 (aroC)

Available reactivities

Ms (Mouse), Rt (Rat), Hu (Human), GP (Guinea Pig), Rb (Rabbit), Eq (Equine)

Available hosts

Rabbit, Goat, Mouse

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunoprecipitation (IP)

Background of HOXB13 antibody

HOXB13 is a novel member of the AbdB subfamily of vertebrate HOX genes which are clustered in 4 unlinked complexes in the genome (HOXA, HOXB, HOXC, and HOXD clusters) which each span about 200 kb and contains 9 to 11 genes, transcribed from the same strand of DNA. The order of the HOX genes along the chromosome correlates with their expression along the anterior/posterior axis of the embryo and suggests that their organization is integral to their proper regulation. Members of the Abdominal B (AbdB) subfamily of homeobox genes exhibit posterior domains of expression, including the developing urogenital system, in vertebrates. Several HOXB genes have been described in humans and other mammals though it was thought that HOXB genes 10 through 13 had been lost in evolution until HOXB13 was discovered.
HOXB13 gene contains 2 exons and encodes a 284-amino acid protein, 2 residues shorter than the mouse protein. It is separated from HOXB9 by 70 kb but is transcribed in the same orientation as the other HOXB genes. The 60-amino acid homeodomain, located near the C terminus of the protein, demonstrated 78 to 83% identity with HOX proteins in paralog group 13 of the AbdB subfamily; 6 of the amino acid differences from other member of this group represented conservative changes. HOXB13 had less than 60% identity to other AbdB-related genes. Mouse Hoxb13 is expressed first in the tailbud of embryonic mice and subsequently in the hindgut, urogenital tract, and the posterior extent of the spinal cord. It is not expressed in the secondary axes.
During the first 2 trimesters of development, wound healing occurs without scars. Two homeobox genes, PRX2 and HOXB13, are differentially expressed during fetal versus adult wound healing. Both genes are expressed in proliferating fibroblasts and fetal dermis, but not in adult dermis.
The HOXB13 gene has been mapped to human chromosome 17q21.2, where other HOXB genes are clustered, whilst the mouse Hoxb13 gene mapped to chromosome 11.

General readings

Zhao Y, Yamashita T, Ishikawa M. Regulation of tumor invasion by HOXB13 gene overexpressed in human endometrial cancer.Oncol Rep. 2005 Apr;13(4):721-6. PMID: 15756448

15 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

HOXB13 antibody

TA303162 (0.1µg/ml) staining of HeLa cell lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

HOXB13 antibody

WB Suggested Anti-Hoxb13 Antibody Titration: 0.2-1 ug/ml; Positive Control: Mouse Thymus Rabbit IgG Purified GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

HOXB13 antibody

WB Suggested Anti-HOXB13 Antibody Titration: 1.25 ug/ml; ELISA Titer: 1:312500; Positive Control: Human Prostate Rabbit IgG Purified Eq, GP, Ms, Rb, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

HOXB13 antibody

HOXB13 Mouse IgG2b 1E9 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

HOXB13 antibody

Western blot analysis of HOXB13, A13 and C13 in HeLa cell lysate in the 1 ) absence and 2 ) presence of immunizing peptide. Using HOXB13 polyclonal antibody ( Cat # PAB0356 ) at 1 : 5000 dilution. Rabbit Hu, Ms, Rt E, WB
0.1 ml / €400.00
  Abnova Taiwan Corp.

HOXB13 antibody

HOXB13 polyclonal antibody ( Cat # PAB7144 ) ( 0.1 µg/ml ) staining of HeLa cell lysate ( 35 µg protein in RIPA buffer ) . Primary incubation was 1 hour. Detected by chemiluminescence. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

HOXB13 (N-term) antibody

Mouse Thymus; WB Suggested Anti-Hoxb13 Antibody Titration: 0.2-1 ug/ml. Positive Control: Mouse Thymus; Hoxb13 antibody - N-terminal region (ARP36889_P050) in Mouse Thymus cells using Western Blot Rabbit Aff - Purified Ms WB
50 µg / €350.00
  AVIVA Systems Biology

HOXB13 antibody

Human Prostate; WB Suggested Anti-HOXB13 Antibody Titration: 1.25ug/ml. ELISA Titer: 1:312500. Positive Control: Human Prostate; HOXB13 antibody - middle region (ARP36890_T100) in Human Prostate cells using Western Blot Rabbit Aff - Purified Ms, Rt WB
0.1 mg / €310.00
  AVIVA Systems Biology

HOXB13 antibody

Western Blot: HOXB13 Antibody [NB100-2492] - Western blot analysis of HOXB13, A13 and C13 in HeLa cell lysate in the 1) absence and 2) presence of immunizing peptide, using NB 100-2492 at 1:5000 dilution. Rabbit Serum Hu, Ms, Rt E, WB
0.1 ml / €320.00
  Novus Biologicals Inc.

HOXB13 antibody

Western Blot: HOXB13 Antibody [NB100-53811] - NB100-53811 (0.1ug/ml) staining of HeLa cell lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat IgG Aff - Purified Hu E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

HOXB13 (1-284, His-tag)

HOXB13 Human Purified > 85 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

HOXB13 (1-284, His-tag)

HOXB13 Human Purified > 85 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

HOXB13

HOXB13 Human
2 µg / €300.00
  Abnova Taiwan Corp.

HOXB13

HOXB13 Human 12.5% SDS-PAGE Stained with Coomassie Blue
10 µg / €380.00
  Abnova Taiwan Corp.

HOXB13

HOXB13 Human 12.5% SDS-PAGE Stained with Coomassie Blue
25 µg / €510.00
  Abnova Taiwan Corp.

15 Item(s)

per page
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