HPV18 E6 Protein antibody

Principal name

HPV18 E6 Protein antibody

Alternative names for HPV18 E6 Protein antibody

Human Papilloma Virus Early Protein 6

SwissProt ID

P06463 (Hpv18)

Gene ID

1489088 (E6)

Available reactivities

Vi (Virus)

Available hosts

Mouse, Rabbit

Available applications

Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Enzyme Immunoassay (E), Radioimmunoassay (R), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of HPV18 E6 Protein antibody

Human papilloma viruses (HPVs) can be classified as either high risk or low risk according to their association with cancer. HPV16 and HPV18 are the most common of the high risk group while HPV6 and HPV11 are among the low risk types. Approximately 90% of cervical cancers contain HPV DNA of the high risk types. Mutational analysis have shown that the E6 and E7 genes of the high risk HPVs are necessary and sufficient for HPV transforming function. The specific interactions of the E6 and E7 proteins with p53 and pRB, respectively, correlate with HPV high and low risk classifications. The high risk HPV E7 proteins bind to pRB with a higher affinity than do the low risk HPV proteins, and only the high risk HPV E6 proteins form detectable complexes with p53 in vitro.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

HPV18 E6 Protein antibody

HPV18 E6 Protein Mouse IgG1 BF7 Purified C, E, R, WB
1 mg / €430.00
  OriGene Technologies GmbH

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per page
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