HS3ST5 / 3OST5 antibody

Principal name

HS3ST5 / 3OST5 antibody

Alternative names for HS3ST5 / 3OST5 antibody

HS3OST5, 3-OST-5, h3-OST-5, Heparan sulfate glucosamine 3-O-sulfotransferase 5, Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 5, Heparan sulfate 3-O-sulfotransferase 5

SwissProt ID

Q8BSL4 (Mouse), Q8IZT8 (Human)

Gene ID

222537 (HS3ST5)

Available reactivities

Bov (Bovine), Can (Canine), Chk (Chicken), Hu (Human), Ms (Mouse), Rt (Rat), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts


Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of HS3ST5 / 3OST5 antibody

HS3ST5 is the rate limiting enzyme for synthesis of HSact. It performs the crucial step modification in the biosynthesis of anticoagulant heparan sulfate (HSact) that is to complete the structure of the antithrombin pentasaccharide binding site. HS3ST5 also generates GlcUA-GlcNS or IdoUA-GlcNS and IdoUA2S-GlcNH2. The substrate-specific O-sulfation generates an enzyme-modified heparan sulfate which acts as a binding receptor to Herpes simplex virus-1 (HSV-1) and permits its entry.HS3ST5 belongs to a group of heparan sulfate 3-O-sulfotransferases (EC that transfer sulfate from 3-prime-phosphoadenosine 5-prime phosphosulfate (PAPS) to heparan sulfate and heparin (Mochizuki et al., 2003 [PubMed 12740361]).[supplied by OMIM]. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-139 AL355498.10 32491-32629 c 140-2744 AL355498.10 25338-27942 c

General readings

Chen,J. (2005) Biochim. Biophys. Acta 1725 (2), 190-200

4 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

HS3ST5 / 3OST5 antibody

WB Suggested Anti-HS3ST5 Antibody Titration: 0.2-1 ug/ml; Positive Control: MCF7 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

HS3ST5 / 3OST5 antibody

Human MCF-7; WB Suggested Anti-HS3ST5 Antibody Titration: 0.2-1 ug/ml. Positive Control: MCF7 cell lysate; HS3ST5 antibody - C-terminal region (ARP49083_P050) in Human MCF-7 cells using Western Blot Rabbit Aff - Purified Bov, Can, Chk, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

HS3ST5 / 3OST5 (full length, N-term HIS tag)

HS3ST5 / 3OST5 Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
50 µg / €199.00
  OriGene Technologies, Inc.


Catalog No.    

HS3ST5 overexpression lysate

HS3ST5 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

4 Item(s)

per page
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