HS3ST5 / 3OST5 antibody

Principal name

HS3ST5 / 3OST5 antibody

Alternative names for HS3ST5 / 3OST5 antibody

HS3OST5, 3-OST-5, h3-OST-5, Heparan sulfate glucosamine 3-O-sulfotransferase 5, Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 5, Heparan sulfate 3-O-sulfotransferase 5

SwissProt ID

Q8BSL4 (Mouse), Q8IZT8 (Human)

Gene ID

222537 (HS3ST5), 319415 (Hs3st5)

Available reactivities

Bov (Bovine), Can (Canine), Chk (Chicken), Hu (Human), Ms (Mouse), Rt (Rat), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB)

Background of HS3ST5 / 3OST5 antibody

HS3ST5 is the rate limiting enzyme for synthesis of HSact. It performs the crucial step modification in the biosynthesis of anticoagulant heparan sulfate (HSact) that is to complete the structure of the antithrombin pentasaccharide binding site. HS3ST5 also generates GlcUA-GlcNS or IdoUA-GlcNS and IdoUA2S-GlcNH2. The substrate-specific O-sulfation generates an enzyme-modified heparan sulfate which acts as a binding receptor to Herpes simplex virus-1 (HSV-1) and permits its entry.HS3ST5 belongs to a group of heparan sulfate 3-O-sulfotransferases (EC 2.8.2.23) that transfer sulfate from 3-prime-phosphoadenosine 5-prime phosphosulfate (PAPS) to heparan sulfate and heparin (Mochizuki et al., 2003 [PubMed 12740361]).[supplied by OMIM]. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-139 AL355498.10 32491-32629 c 140-2744 AL355498.10 25338-27942 c

General readings

Chen,J. (2005) Biochim. Biophys. Acta 1725 (2), 190-200

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

HS3ST5 / 3OST5 antibody

  Rabbit polyclonal Anti-HS3ST5 Antibody  
WB Suggested Anti-HS3ST5 Antibody Titration: 0.2-1 ug/ml; Positive Control: MCF7 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

CRISPR

Catalog No. Species Donor Vector  

HS3ST5 - human gene knockout kit via CRISPR

HS3ST5 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

HS3ST5 - human gene knockout kit via CRISPR

HS3ST5 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

HS3ST5 - human gene knockout kit via CRISPR

HS3ST5 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

HS3ST5 - human gene knockout kit via CRISPR

HS3ST5 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

HS3ST5 / 3OST5 (full length, N-term HIS tag)

  Purified recombinant protein of Human heparan sulfate (glucosamine) 3-O-sulfotransferase 5 (HS3ST5), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug  
HS3ST5 / 3OST5 Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
50 µg / €199.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

HS3ST5 overexpression lysate

HS3ST5 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, HS3ST5 (mGFP-tagged) - Human heparan sulfate (glucosamine) 3-O-sulfotransferase 5 (HS3ST5), 200 uL, >10^7 TU/mL

Lenti ORF particles, HS3ST5 (mGFP-tagged) - Human heparan sulfate (glucosamine) 3-O-sulfotransferase 5 (HS3ST5), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, HS3ST5 (Myc-DDK tagged) - Human heparan sulfate (glucosamine) 3-O-sulfotransferase 5 (HS3ST5) , 200 uL, >10^7 TU/mL

Lenti ORF particles, HS3ST5 (Myc-DDK tagged) - Human heparan sulfate (glucosamine) 3-O-sulfotransferase 5 (HS3ST5) , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Hs3st5 (Myc-DDK-tagged) - Mouse heparan sulfate (glucosamine) 3-O-sulfotransferase 5 (Hs3st5), 200 uL, >10^7 TU/mL

Lenti ORF particles, Hs3st5 (Myc-DDK-tagged) - Mouse heparan sulfate (glucosamine) 3-O-sulfotransferase 5 (Hs3st5), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

10 Item(s)

per page
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