HSD17B10 / ERAB antibody

Principal name

HSD17B10 / ERAB antibody

Alternative names for HSD17B10 / ERAB antibody

HADH2, MRPP2, SCHAD, XH98G2, 17-beta-HSD10, Mitochondrial Marker, 17-beta-hydroxysteroid dehydrogenase 10, Endoplasmic reticulum-associated amyloid beta-peptide-binding protein, 3-hydroxyacyl-CoA dehydrogenase type-2, 3-hydroxyacyl-CoA dehydrogenase type II, Type II HADH, 3-hydroxy-2-methylbutyryl-CoA dehydrogenase, Mitochondrial ribonuclease P protein 2, Short-chain type dehydrogenase/reductase XH98G2

SwissProt ID

O02691 (Bovin), O08756 (Mouse), O18404 (Drome), O70351 (Rat), Q99714 (Human)

Gene ID

3028 (HSD17B10)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Mky (Monkey), Xen (Xenopus), Ze (Zebrafish), Por (Porcine)

Available hosts

Mouse, Rabbit, Goat

Available applications

Frozen Sections (C), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Western blot / Immunoblot (WB), Flow Cytometry (F), Immunoprecipitation (IP), ELISA (detection) (E(detection))

Background of HSD17B10 / ERAB antibody

This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids, alcohols, and steroids. The protein has been implicated in the development of Alzheimer's disease, and mutations in the gene are the cause of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency (MHBD). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq]. Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1, resulting in a shorter isoform (2). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

He XY, Schulz H, Yang SY. A human brain L-3-hydroxyacyl-coenzyme A dehydrogenase is identical to an amyloid beta-peptide-binding protein involved in Alzheimer's disease.
J Biol Chem. 1998 Apr 24;273(17):10741-6. PMID: 9553139

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

HSD17B10 / ERAB antibody

Immunohistochemical staining of paraffin-embedded liver tissue within the normal limits using anti-HSD17B10mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500686, Dilution 1:50) Mouse IgG1 OTI10B4 Purified Hu F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

HSD17B10 / ERAB antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of Human thyroid tissue using anti-HSD17B10 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500724) Mouse IgG2b OTI11A2 Purified Hu F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

HSD17B10 / ERAB antibody

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of breast tissue using anti-HSD17B10 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500813, Dilution 1:50) Mouse IgG2a OTI5E2 Purified Hu, Mky F, ICC/IF, P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

HSD17B10 / ERAB (100-116) antibody

Human Alzheimer’s brain stained with anti-ERAB antibody Rabbit Purified Hu P, WB
0.5 ml / €360.00
  Acris Antibodies GmbH

HSD17B10 / ERAB (100-116) antibody

Human Alzheimer’s brain stained with anti-ERAB antibody Rabbit Purified Hu P, WB
1 ml / €520.00
  Acris Antibodies GmbH

HSD17B10 / ERAB (100-116) antibody

Human Alzheimer’s brain stained with anti-ERAB antibody Rabbit Purified Hu P, WB
0.1 ml / €190.00
  Acris Antibodies GmbH

HSD17B10 / ERAB antibody

TA302984 staining (0.3µg/ml) of Human Brain lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Mky, Ms, Rt, Xen, Ze WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

HSD17B10 / ERAB antibody

Western blot analysis of Jurkat cells (Lane 1: 50ug lysate), EC9706 cells (Lane 2: 57ug lysate) and SGC cells (Lane 3: 50ug lysate) with anti-HADH2 antibody diluated at 1:1000. Rabbit IgG Purified Hu, Ms WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

HSD17B10 / ERAB antibody

Western blot analysis of ABAD/HADH2 using Jurkat cell lysate (Lane 1& 2). Rabbit Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

HSD17B10 / ERAB antibody

Western blot analysis of ERAB/HCD2 using rat kidney tissue lysate (Lane 1), mouse 3T3 cell lysate (Lane 2) and Jurkat cell lysate (Lane 3 & 4). Rabbit Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

HSD17B10 / ERAB antibody

Western blot analysis of extracts from LOVO cells, using ERAB antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

HSD17B10 / ERAB antibody

Western blot analysis of extracts of various cell lines, using HSD17B10 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

HSD17B10 / ERAB antibody

Western blot analysis of extract from JK, HUVEC, HepG2 and Hela cells using ERAB Antibody Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

HSD17B10 / ERAB antibody

Immunohistochemical staining of paraffin-embedded liver tissue within the normal limits using anti-HSD17B10 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500687, Dilution 1:50) Mouse IgG1 OTI3B5 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

HSD17B10 / ERAB (C-term) antibody

Immunohistochemistry on Formalin-fixed and paraffin-embedded human prostate tissue. (Top)Coloration with the Anti-ABAD antibody at a 1:20 concentration. (Bottom)Antibody adsorbed to the antigen (peptide), negative control.Disappearance of cytoplasmic staining indicating the antibody is specific. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

HSD17B10 / ERAB antibody

Immunohistochemistry analyzes of HADH2 antibody (AP20285PU-N) in paraffin-embedded human brain tissue. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

HSD17B10 / ERAB antibody

HSD17B10 / ERAB Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

HSD17B10 / ERAB antibody

Immunofluorescence of purified MaxPab antibody to HADH2 on HeLa cell. [antibody concentration 10 ug/ml] Mouse Serum Hu E(detection), ICC/IF, WB
50 µl / €370.00
  Abnova Taiwan Corp.

HSD17B10 / ERAB antibody

Immunofluorescence of purified MaxPab antibody to HADH2 on HeLa cell. [antibody concentration 10 ug/ml] Mouse Purified Hu E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

HSD17B10 / ERAB antibody

Western Blot analysis of HSD17B10 expression in transfected 293T cell line (H00003028-T02) by HSD17B10 MaxPab polyclonal antibody.

Lane 1: HSD17B10 transfected lysate(26.90 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

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