HSPB8 / HSP22 antibody

Principal name

HSPB8 / HSP22 antibody

Alternative names for HSPB8 / HSP22 antibody

Heat shock protein beta-8, CRYAC, E2IG1, Small stress protein-like protein HSP22, Alpha-crystallin C chain, E2-induced gene 1 protein, Protein kinase H11

SwissProt ID

Q5EAC9 (Bovin), Q8MJ36 (Canfa), Q9EPX0 (Rat), Q9JK92 (Mouse), Q9UJY1 (Human)

Gene ID

26353 (HSPB8)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Ms (Mouse), Rt (Rat), Mky (Monkey), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Mouse, Goat, Rabbit

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), ELISA (detection) (E(detection)), Dot blot (Dot), Flow Cytometry (F)

Background of HSPB8 / HSP22 antibody

HSPB8 belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-termil part of the molecule. The expression of HSPB8 protein is induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, HSPB8 appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in the encoding HSPB8 gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-termil part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additiol publications.

General readings

Benndorf R, Sun X, Gilmont RR, Biederman KJ, Molloy MP, Goodmurphy CW, Cheng H, Andrews PC, Welsh MJ.
HSP22, a new member of the small heat shock protein superfamily, interacts with mimic of phosphorylated HSP27 ((3D)HSP27).
J Biol Chem. 2001 Jul 20;276(29):26753-61.
PMID: 11342557

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

HSPB8 / HSP22 antibody

Anti-HSPB8 mouse monoclonal antibody (TA501210) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY HSPB8(RC201040 ). Mouse IgG2a OTI1E3 Purified Hu, Rt F, ICC/IF, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

HSPB8 / HSP22 (C-term) antibody

TA302835 staining (1µg/ml) of human muscle lysate (RIPA buffer, 30µg total protein per lane).  Primary incubated for 1 hour.  Detected by western blot using chemiluminescence. Goat Aff - Purified Hu E, WB
20 µg / €200.00
  Acris Antibodies GmbH

HSPB8 / HSP22 (C-term) antibody

TA302835 staining (1µg/ml) of human muscle lysate (RIPA buffer, 30µg total protein per lane).  Primary incubated for 1 hour.  Detected by western blot using chemiluminescence. Goat Aff - Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

HSPB8 / HSP22 antibody

Sample(30 ug whole cell lysate). A:293T whole cell lysate. B:A431. 12% SDS PAGE. TA308596 diluted at 1:1000 Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

HSPB8 / HSP22 antibody

Western blot analysis of Hsp22 in rat skeletal muscle lysates using 20ug of the antibody Rabbit Purified Hu, Ms WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

HSPB8 / HSP22 antibody

WB Suggested Anti-HSPB8 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: Human Placenta Rabbit IgG Purified Bov, Eq, GP, Hu, Ms, Por, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

HSPB8 / HSP22 antibody

WB Suggested Anti-HSPB8 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: ACHN cell lysateHSPB8 is supported by BioGPS gene expression data to be expressed in ACHN Rabbit IgG Purified Can, Eq, GP, Hu, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

HSPB8 / HSP22 antibody

Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE) Mouse IgG 5B12 Purified Hu E, P, WB
50 µg / €530.00
  Acris Antibodies GmbH

HSPB8 / HSP22 antibody

HSPB8 / HSP22 Mouse Serum Hu E
50 µl / €290.00
  Abnova Taiwan Corp.

HSPB8 / HSP22 antibody

HSPB8 MaxPab polyclonal antibody. Western Blot analysis of HSPB8 expression in human colon. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

HSPB8 / HSP22 antibody

HSPB8 MaxPab polyclonal antibody. Western Blot analysis of HSPB8 expression in human colon. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

HSPB8 / HSP22 antibody

Western Blot analysis of HSPB8 expression in transfected 293T cell line by HSPB8 monoclonal antibody (M02), clone 5D7.

Lane 1: HSPB8 transfected lysate(35.446 KDa).
Lane 2: Non-transfected lysate. Mouse IgG2b 5D7 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

HSPB8 / HSP22 antibody

Western Blot analysis of HSPB8 expression in transfected 293T cell line by HSPB8 monoclonal antibody (M03), clone 5C3.

Lane 1: HSPB8 transfected lysate(35.446 KDa).
Lane 2: Non-transfected lysate. Mouse IgG2b 5C3 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

HSPB8 / HSP22 antibody

Immunoperoxidase of monoclonal antibody to HSPB8 on formalin-fixed paraffin-embedded human placenta. [antibody concentration 3 ug/ml] Mouse IgG 5B12 Purified Hu E, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

HSPB8 / HSP22 antibody

HSPB8 / HSP22 Mouse IgG2a 5B12 Ascites Hu E, WB
0.2 ml / €370.00
  Abnova Taiwan Corp.

HSPB8 / HSP22 antibody

Western Blot analysis of HSPB8 expression in transfected 293T cell line by HSPB8 monoclonal antibody (M05), clone 5G3.

Lane 1: HSPB8 transfected lysate(35.446 KDa).
Lane 2: Non-transfected lysate. Mouse IgG3 5G3 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

HSPB8 / HSP22 antibody

HSPB8 monoclonal antibody (M12), clone 3C5. Western Blot analysis of HSPB8 expression in HeLa(Cat # L013V1 ). Mouse IgG1 3C5 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

HSPB8 / HSP22 antibody

HSPB8 polyclonal antibody ( Cat # PAB6266 ) staining ( 1 µg/ml ) of human muscle lysate ( RIPA buffer, 30 µg total protein per lane ) . Primary incubated for 1 hour. Detected by western blot using chemiluminescence. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

HSPB8 / HSP22 antibody

Human Placenta; WB Suggested Anti-HSPB8 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: Human Placenta; HSPB8 antibody - N-terminal region (ARP55035_P050) in Human Placenta cells using Western Blot Rabbit Aff - Purified Bov, Can, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

HSPB8 / HSP22 (Center) antibody

Human ACHN; WB Suggested Anti-HSPB8 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: ACHN cell lysate. HSPB8 is supported by BioGPS gene expression data to be expressed in ACHN.; HSPB8 antibody - middle region (ARP55036_P050) in Human ACHN cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

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