HSPB8 / HSP22 antibody

Principal name

HSPB8 / HSP22 antibody

Alternative names for HSPB8 / HSP22 antibody

Heat shock protein beta-8, CRYAC, E2IG1, Small stress protein-like protein HSP22, Alpha-crystallin C chain, E2-induced gene 1 protein, Protein kinase H11

SwissProt ID

Q5EAC9 (Bovin), Q8MJ36 (Canfa), Q9EPX0 (Rat), Q9JK92 (Mouse), Q9UJY1 (Human)

Gene ID

26353 (HSPB8), 80888 (Hspb8), 113906

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Ms (Mouse), Rt (Rat), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Mouse, Goat, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of HSPB8 / HSP22 antibody

HSPB8 belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-termil part of the molecule. The expression of HSPB8 protein is induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, HSPB8 appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in the encoding HSPB8 gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-termil part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additiol publications.

General readings

Benndorf R, Sun X, Gilmont RR, Biederman KJ, Molloy MP, Goodmurphy CW, Cheng H, Andrews PC, Welsh MJ.
HSP22, a new member of the small heat shock protein superfamily, interacts with mimic of phosphorylated HSP27 ((3D)HSP27).
J Biol Chem. 2001 Jul 20;276(29):26753-61.
PMID: 11342557

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

HSPB8 / HSP22 antibody

  HSPB8 (Hsp22) mouse monoclonal antibody, clone OTI1E3 (formerly 1E3)  
Anti-HSPB8 mouse monoclonal antibody (TA501210) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY HSPB8(RC201040 ). Mouse IgG2a OTI1E3 Purified Hu, Rt F, ICC/IF, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

HSPB8 / HSP22 (C-term) antibody

  Goat Polyclonal Antibody against HSPB8  
TA302835 staining (1µg/ml) of human muscle lysate (RIPA buffer, 30µg total protein per lane).  Primary incubated for 1 hour.  Detected by western blot using chemiluminescence. Goat Aff - Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

HSPB8 / HSP22 antibody

  Rabbit Polyclonal antibody to HSP22 (heat shock 22kDa protein 8)  
Sample(30 ug whole cell lysate). A:293T whole cell lysate. B:A431. 12% SDS PAGE. TA308596 diluted at 1:1000 Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

HSPB8 / HSP22 antibody

  Rabbit polyclonal Hsp22 Antibody  
Western blot analysis of Hsp22 in rat skeletal muscle lysates using 20ug of the antibody Rabbit Purified Hu, Ms WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

HSPB8 / HSP22 antibody

  Rabbit Polyclonal Anti-HSPB8 Antibody  
WB Suggested Anti-HSPB8 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: Human Placenta Rabbit IgG Purified Bov, Eq, GP, Hu, Ms, Por, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

HSPB8 / HSP22 antibody

  Rabbit Polyclonal Anti-HSPB8 Antibody  
WB Suggested Anti-HSPB8 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: ACHN cell lysateHSPB8 is supported by BioGPS gene expression data to be expressed in ACHN Rabbit IgG Purified Can, Eq, GP, Hu, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

HSPB8 / HSP22 antibody

  Rabbit Polyclonal Anti-HSPB8 Antibody  
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using (HSPB8 Antibody) at dilution 1/45, on the right is treated with fusion protein. (Original magnification: ×200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

HSPB8 / HSP22 antibody

Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE) Mouse IgG 5B12 Purified Hu E, P, WB
50 µg / €530.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

HSPB8 - human gene knockout kit via CRISPR

HSPB8 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

HSPB8 - human gene knockout kit via CRISPR

HSPB8 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

HSPB8 - human gene knockout kit via CRISPR

HSPB8 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

HSPB8 - human gene knockout kit via CRISPR

HSPB8 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Hspb8 - mouse gene knockout kit via CRISPR

Hspb8 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Hspb8 - mouse gene knockout kit via CRISPR

Hspb8 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Hspb8 - mouse gene knockout kit via CRISPR

Hspb8 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Hspb8 - mouse gene knockout kit via CRISPR

Hspb8 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

HSPB8 / HSP22

  Recombinant protein of human heat shock 22kDa protein 8 (HSPB8)  
HSPB8 / HSP22 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

HSPB8 / HSP22 (1-196, His-tag)

HSPB8 / HSP22 Human Purified > 95 % by SDS - PAGE E. coli
0.25 mg / €1,000.00
  Acris Antibodies GmbH

HSPB8 / HSP22 (1-196, His-tag)

HSPB8 / HSP22 Human Purified > 95 % by SDS - PAGE E. coli
50 µg / €370.00
  Acris Antibodies GmbH

HSPB8 / HSP22

HSPB8 / HSP22 Human Purified > 95 % E. coli
0.1 mg / €1,750.00
  HyTest Ltd.

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