HSPG2 / Perlecan antibody

Principal name

HSPG2 / Perlecan antibody

Alternative names for HSPG2 / Perlecan antibody

PLC, Basement membrane-specific heparan sulfate proteoglycan core protein

SwissProt ID

P98160 (Human), Q05793 (Mouse)

Gene ID

3339 (HSPG2)

Available reactivities

Bov (Bovine), Hu (Human), Ms (Mouse), Rt (Rat), Cod, Wolf (Wolffish), Por (Porcine)

Available hosts

Rat, Mouse, Rabbit

Available applications

Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E)

Background of HSPG2 / Perlecan antibody

This gene encodes the perlecan protein, which consists of a core protein to which three long chains of glycosaminoglycans(heparan sulfate or chondroitin sulfate) are attached. The perlecan protein is a large multidomain proteoglycan that binds to and cross-links many extracellular matrix components and cell-surface molecules. It has been shown that this protein interacts with laminin, prolargin, collagen type IV, FGFBP1, FBLN2, FGF7 and Transthyretin, etc. and plays essential roles in multiple biological activities. Perlecan is a key component of the vascular extracellular matrix, where it helps to maintain the endothelial barrier function. It is a potent inhibitor of smooth muscle cell proliferation and is thus thought to help maintain vascular homeostasis. It can also promote growth factor (e.g., FGF2) activity and thus stimulate endothelial growth and re-generation. It is a major component of basement membranes, where it is involved in the stabilization of other molecules as well as being involved with glomerular permeability to macromolecules and cell adhesion. Mutations in this gene cause Schwartz-Jampel syndrome type 1, Silverman-Handmaker type of dyssegmental dysplasia, and Tardive dyskinesia.[provided by RefSeq, Mar 2010].

7 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

HSPG2 / Perlecan antibody

Immunohistochemistry on Frozen Section of Human kidney showing strong reactivity in the extracellular matrix and basement membrane. Rat IgG2a A7L6 Purified Bov, Cod, Hu, Ms, Rt, Wolf C, ICC/IF, IP, P, WB
0.1 mg / €320.00
  Acris Antibodies GmbH

HSPG2 / Perlecan antibody

HSPG2 / Perlecan Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

HSPG2 / Perlecan antibody

Frozen human tonsil stained with NeoMarkers' Heparan Sulfate Proteoglycan Ab-1 using peroxidase-conjugate and DAB chromogen. Note basement membrane and cell surface staining of blood vessels. Rat IgG2a A7L6 Supernatant Bov, Hu, Ms, Por C, ICC/IF, P
0.5 ml / €440.00
  Novus Biologicals Inc.

HSPG2 / Perlecan antibody

HSPG2 / Perlecan Mouse IgG1 Purified Bov, Hu C, E, IP, P
0.1 mg / €450.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

HSPG2 / Perlecan

HSPG2 / Perlecan Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

HSPG2 / Perlecan

HSPG2 / Perlecan Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates (Overexpressed)

Catalog No.    

HSPG2 overexpression lysate

HSPG2 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

7 Item(s)

per page
  • LinkedIn