HTRA1 / PRSS11 antibody

Principal name

HTRA1 / PRSS11 antibody

Alternative names for HTRA1 / PRSS11 antibody

HTRA, L56, Serine protease 11, Serine protease HTRA1

SwissProt ID

Q92743 (Human), Q9R118 (Mouse)

Gene ID

5654 (HTRA1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Frozen Sections (C)

Background of HTRA1 / PRSS11 antibody

The defining features of the widely conserved HtrA (high temperature requirement) family of serine proteases are the combination of a catalytic protease domain with one or more C-terminal PDZ domains and reversible zymogen activation. Even though HtrAs have previously been implicated in a cell's protein quality control and various diseases, including cancer, arthritis, and neuromuscular disorder, the biology of the human family members is not well understood. New studies suggest that HtrA1 is directly involved in the amyloid pathway as it degrades various fragments of amyloid precursor protein while an HtrA1 inhibitor causes accumulation of amyloid beta in astrocyte cell culture supernatants. Furthermore, HtrA1 colocalizes with amyloid deposits in human brain samples.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

HTRA1 / PRSS11 (N-term) antibody

The anti-HtrA1 N-term Pab (Cat. #TA324517) is used in Western blot to detect HtrA1in mouse brain tissue lysate. Rabbit Ig Purified Hu, Ms ICC/IF, P, WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

HTRA1 / PRSS11 (C-term) antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Purified Hu P, WB

Regular Price: 0.4 ml / €370.00

Special Price: 0.4 ml / €231.00

  Acris Antibodies GmbH

HTRA1 / PRSS11 antibody

The HTRA1 polyclonal antibody ( Cat # PAB2455 ) is used in Western blot to detect HTRA1 mouse brain tissue lysate. Rabbit Hu, Ms E, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

HTRA1 / PRSS11 antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the HTRA1 polyclonal antibody ( Cat # PAB2456 ) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. BC = breast carcinoma. Rabbit Hu E, P, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

HTRA1 / PRSS11 antibody

Immunohistochemistry-Paraffin: htrA1 Antibody [NBP1-81654] Immunohistochemical staining of human kidney shows strong cytoplasmic and membranous positivity in cells in tubules. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

HTRA1 / PRSS11

HTRA1 /  PRSS11 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

HTRA1 / PRSS11

HTRA1 /  PRSS11 Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

HTRA1 overexpression lysate

HTRA1 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

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