HUWE1 / UREB1 antibody

Principal name

HUWE1 / UREB1 antibody

Alternative names for HUWE1 / UREB1 antibody

URE-binding protein 1, URE-B1, Mule, ARF-BP1, LASU1, HectH9, KIAA0312, KIAA1578, HSPC272, E3 ubiquitin-protein ligase HUWE1, HECT, UBA and WWE domain-containing protein 1, Upstream regulatory element-binding protein 1, Mcl-1 ubiquitin ligase E3, ARF-binding protein 1, Large structure of UREB1, Homologous to E6AP carboxyl terminus homologous protein 9

SwissProt ID

P51593 (Rat), Q7TMY8 (Mouse), Q7Z6Z7 (Human)

Gene ID

10075 (HUWE1), 1100756 (P23153)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse, Goat

Available applications

Paraffin Sections (P), Immunoprecipitation (IP), PLA/Proximity ligation assay (PLA), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of HUWE1 / UREB1 antibody

The ARF tumor suppressor is a critical regulator of p53 stability. In addition to p53, ARF1 binds to other proteins such as MDM2 and ARF-BP1, a large protein containing HECT, UBA and WWE motifs. ARF-BP1 directly binds and ubiquitinates p53; this activity is inhibited by ARF, indicating that ARF-BP1 is a critical mediator of the p53-dependent and p53-independent tumor suppressor functions of ARF. ARF-BP1 can also catalyze the polyubiquitination of Mcl-1, an anti-apoptotic Bcl-2 family member involved in DNA damage-induced apoptosis. Elimination of ARF-BP1 expression by RNA interference stabilized Mcl-1 protein, resulting in an attenuation of apoptosis induced by DNA-damage agents.

  1. Quick-Filters:
  2. Cited (1)

7 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

HUWE1 / UREB1 (C-term) antibody

Heart: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit IgG Aff - Purified Hu, Ms, Rt P, WB
50 µg / €470.00
  Acris Antibodies GmbH

HUWE1 / UREB1 antibody

Western blot analysis of ARF-BP1 in Daudi cell lysate with ARF-BP1 antibody at 1 ug/mL. Rabbit IgG Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

HUWE1 / UREB1 Control Peptide

HUWE1  / UREB1
50 µg / €160.00
  Acris Antibodies GmbH

HUWE1 / UREB1 antibody

HUWE1  / UREB1 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

HUWE1 / UREB1 antibody

Immunocytochemistry of HUWE1 in Daudi cells with HUWE1 polyclonal antibody ( Cat # PAB12996 ) at 5 µg/ml. Rabbit Hu, Ms, Rt ICC/IF, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

HUWE1 / UREB1

HUWE1  / UREB1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

HUWE1 / UREB1

HUWE1  / UREB1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

7 Item(s)

per page
  • LinkedIn