HYAL1 / Hyaluronidase-1 antibody

Principal name

HYAL1 / Hyaluronidase-1 antibody

Alternative names for HYAL1 / Hyaluronidase-1 antibody

LUCA1, Hyal-1, Hyaluronoglucosaminidase-1, Lung carcinoma protein 1

SwissProt ID

Q12794 (Human), Q5E985 (Bovin), Q6RHW4 (Pig), Q76HN1 (Rat), Q8NFK8 (Human), Q91ZJ9 (Mouse)

Gene ID

3373 (HYAL1), 15586 (Hyal1), 367166

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Por (Porcine), Can (Canine), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Mouse, Goat, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Paraffin Sections (P)

Background of HYAL1 / Hyaluronidase-1 antibody

HYAL1 is a lysosomal hyaluronidase. Hyaluronidases intracellularly degrade hyaluron, one of the major glycosaminoglycans of the extracellular matrix. Hyaluron is thought to be involved in cell proliferation, migration and differentiation. This enzyme is active at an acidic pH and is the major hyaluronidase in plasma. Mutations in this gene are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency. This gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. Multiple transcript variants encoding different isoforms have been found for this gene.This gene encodes a lysosomal hyaluronidase. Hyaluronidases intracellularly degrade hyaluron, one of the major glycosaminoglycans of the extracellular matrix. Hyaluron is thought to be involved in cell proliferation, migration and differentiation. This enzyme is active at an acidic pH and is the major hyaluronidase in plasma. Mutations in this gene are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. Multiple transcript variants encoding different isoforms have been found for this gene.

General readings

Lanktree, M.B., et al. Blood 116(12):2160-2163(2010)
Gasingirwa, M.C., et al. Biochem. J. 430(2):305-313(2010)
Tzuman, Y.C., et al. Neoplasia 12(1):51-60(2010)
Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010)
Wang, X.Y., et al. Chin. Med. J. 122(11):1300-1304(2009)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

HYAL1 / Hyaluronidase-1 antibody

  Rabbit Polyclonal Anti-HYAL1 Antibody  
Host: Rabbit; Target Name: HYAL1; Sample Tissue: Human Fetal Lung; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

HYAL1 / Hyaluronidase-1 antibody

  Rabbit Polyclonal Anti-HYAL1 Antibody  
WB Suggested Anti-HYAL1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: Human brain Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

HYAL1 / Hyaluronidase-1 (C-term) antibody

Immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue reacted with HYAL1 / Hyaluronidase-1 Antibody (C-term) Cat.-No AP52132PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining. Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

HYAL1 - human gene knockout kit via CRISPR

HYAL1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

HYAL1 - human gene knockout kit via CRISPR

HYAL1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

HYAL1 - human gene knockout kit via CRISPR

HYAL1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

HYAL1 - human gene knockout kit via CRISPR

HYAL1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Hyal1 - mouse gene knockout kit via CRISPR

Hyal1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Hyal1 - mouse gene knockout kit via CRISPR

Hyal1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

HYAL1 / Hyaluronidase-1 (transcript variant 7)

  Recombinant protein of human hyaluronoglucosaminidase 1 (HYAL1), transcript variant 7  
HYAL1 / Hyaluronidase-1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

HYAL1 / Hyaluronidase-1 (transcript variant 5)

  Purified recombinant protein of Human hyaluronoglucosaminidase 1 (HYAL1), transcript variant 5  
HYAL1 / Hyaluronidase-1 Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
10 µg / €139.00
  OriGene Technologies, Inc.

Hyaluronidase

Hyaluronidase Bovine Purified
0.5 g / €250.00
  Acris Antibodies GmbH

Lysates

Catalog No.    

HYAL1 overexpression lysate

HYAL1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

HYAL1 overexpression lysate

HYAL1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, HYAL1 (mGFP-tagged) - Human hyaluronoglucosaminidase 1 (HYAL1), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, HYAL1 (mGFP-tagged) - Human hyaluronoglucosaminidase 1 (HYAL1), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, HYAL1 (mGFP-tagged) - Human hyaluronoglucosaminidase 1 (HYAL1), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, HYAL1 (mGFP-tagged) - Human hyaluronoglucosaminidase 1 (HYAL1), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,000.00
  OriGene Technologies, Inc.

Lenti ORF particles, HYAL1 (mGFP-tagged)-Human hyaluronoglucosaminidase 1 (HYAL1), transcript variant 5, 200 uL, >10^7 TU/mL

Lenti ORF particles, HYAL1 (mGFP-tagged)-Human hyaluronoglucosaminidase 1 (HYAL1), transcript variant 5, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, HYAL1 (mGFP-tagged) - Human hyaluronoglucosaminidase 1 (HYAL1), transcript variant 8, 200 uL, >10^7 TU/mL

Lenti ORF particles, HYAL1 (mGFP-tagged) - Human hyaluronoglucosaminidase 1 (HYAL1), transcript variant 8, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, HYAL1 (Myc-DDK tagged) - Human hyaluronoglucosaminidase 1 (HYAL1), transcript variant 1 , 200 uL, >10^7 TU/mL

Lenti ORF particles, HYAL1 (Myc-DDK tagged) - Human hyaluronoglucosaminidase 1 (HYAL1), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Lenti ORF particles, HYAL1 (Myc-DDK tagged) - Human hyaluronoglucosaminidase 1 (HYAL1), transcript variant 2 , 200 uL, >10^7 TU/mL

Lenti ORF particles, HYAL1 (Myc-DDK tagged) - Human hyaluronoglucosaminidase 1 (HYAL1), transcript variant 2 , 200 uL, >10^7 TU/mL  
200 µl / €890.00
  OriGene Technologies, Inc.

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