HYAL1 / Hyaluronidase-1 antibody

Principal name

HYAL1 / Hyaluronidase-1 antibody

Alternative names for HYAL1 / Hyaluronidase-1 antibody

LUCA1, Hyal-1, Hyaluronoglucosaminidase-1, Lung carcinoma protein 1

SwissProt ID

Q12794 (Human), Q5E985 (Bovin), Q6RHW4 (Pig), Q76HN1 (Rat), Q8NFK8 (Human), Q91ZJ9 (Mouse)

Gene ID

3373 (HYAL1), 15586 (Hyal1), 367166

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine), Bov (Bovine), Por (Porcine), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Mouse, Goat, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of HYAL1 / Hyaluronidase-1 antibody

HYAL1 is a lysosomal hyaluronidase. Hyaluronidases intracellularly degrade hyaluron, one of the major glycosaminoglycans of the extracellular matrix. Hyaluron is thought to be involved in cell proliferation, migration and differentiation. This enzyme is active at an acidic pH and is the major hyaluronidase in plasma. Mutations in this gene are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency. This gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. Multiple transcript variants encoding different isoforms have been found for this gene.This gene encodes a lysosomal hyaluronidase. Hyaluronidases intracellularly degrade hyaluron, one of the major glycosaminoglycans of the extracellular matrix. Hyaluron is thought to be involved in cell proliferation, migration and differentiation. This enzyme is active at an acidic pH and is the major hyaluronidase in plasma. Mutations in this gene are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. Multiple transcript variants encoding different isoforms have been found for this gene.

General readings

Lanktree, M.B., et al. Blood 116(12):2160-2163(2010)
Gasingirwa, M.C., et al. Biochem. J. 430(2):305-313(2010)
Tzuman, Y.C., et al. Neoplasia 12(1):51-60(2010)
Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010)
Wang, X.Y., et al. Chin. Med. J. 122(11):1300-1304(2009)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

HYAL1 / Hyaluronidase-1 antibody

Host: Rabbit; Target Name: HYAL1; Sample Tissue: Human Fetal Lung; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

HYAL1 / Hyaluronidase-1 antibody

Human Liver; Immunohistochemistry with Human Liver cell lysate tissue at an antibody concentration of 5.0ug/ml using anti-HYAL1 antibody (ARP50812_P050); HYAL1 antibody - N-terminal region (ARP50812_P050) in Human Liver cells using Immunohistochemistry Rabbit Aff - Purified Bov, Hu, Ms, Por, Rt P, WB
50 µg / €350.00
  AVIVA Systems Biology

HYAL1 / Hyaluronidase-1 antibody

WB Suggested Anti-HYAL1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: Human brain Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

HYAL1 / Hyaluronidase-1 (325-339) antibody

Liver: Formalin-Fixed, Paraffin-Embedded (FFPE) Goat IgG Aff - Purified Bear, Bt, Can, Elephant, Eq, Hu, Mky, Por, Prim E, P
50 µg / €470.00
  Acris Antibodies GmbH

HYAL1 / Hyaluronidase-1 (C-term) antibody

Immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue reacted with HYAL1 / Hyaluronidase-1 Antibody (C-term) Cat.-No AP52132PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining. Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

HYAL1 / Hyaluronidase-1 antibody

HYAL1 / Hyaluronidase-1 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

HYAL1 / Hyaluronidase-1 antibody

Western Blot analysis of HYAL1 expression in transfected 293T cell line (H00003373-T01) by HYAL1 MaxPab polyclonal antibody.

Lane 1: HYAL1 transfected lysate(27.83 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

HYAL1 / Hyaluronidase-1 antibody

Western Blot analysis of HYAL1 expression in transfected 293T cell line (H00003373-T01) by HYAL1 MaxPab polyclonal antibody.

Lane 1: HYAL1 transfected lysate(28.00 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

HYAL1 / Hyaluronidase-1 antibody

Detection limit for recombinant GST tagged HYAL1 is approximately 1ng/ml as a capture antibody. Mouse IgG2a 2H7 Purified Hu E
0.1 mg / €370.00
  Abnova Taiwan Corp.

HYAL1 / Hyaluronidase-1 antibody

HYAL1 / Hyaluronidase-1 Goat Ms, Rt E
0.1 mg / €390.00
  Abnova Taiwan Corp.

HYAL1 / Hyaluronidase-1 antibody

HYAL1 / Hyaluronidase-1 Goat Hu E
0.1 mg / €390.00
  Abnova Taiwan Corp.

HYAL1 / Hyaluronidase-1 antibody

Human Brain; WB Suggested Anti-HYAL1 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: Human brain; HYAL1 antibody - N-terminal region (ARP50813_P050) in Human Brain cells using Western Blot Rabbit Aff - Purified Bov, Hu, Ms, Por, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

HYAL1 / Hyaluronidase-1 antibody

Western Blot: HYAL1 Antibody [NBP1-32465] - (30 ug whole cell lysate) A:293T 7.5% SDS PAGE diluted at 1:1000 Rabbit IgG Hu P, WB
0.1 mg / €420.00
  Novus Biologicals Inc.

HYAL1 / Hyaluronidase-1 antibody

Immunohistochemistry-Paraffin: HYAL1 Antibody [NBP1-83409] - Immunohistochemical staining of human corpus, uterine shows strong cytoplasmic positivity in glandular cells. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

HYAL1 / Hyaluronidase-1 (transcript variant 7)

HYAL1 / Hyaluronidase-1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

HYAL1 / Hyaluronidase-1 (transcript variant 5)

HYAL1 / Hyaluronidase-1 Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
10 µg / €139.00
  OriGene Technologies, Inc.

HYAL1 / Hyaluronidase-1

HYAL1 / Hyaluronidase-1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

HYAL1 / Hyaluronidase-1

HYAL1 / Hyaluronidase-1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

HYAL1 / Hyaluronidase-1

HYAL1 / Hyaluronidase-1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

HYAL1 / Hyaluronidase-1

HYAL1 / Hyaluronidase-1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

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