HYAL2 / Hyaluronidase-2 antibody

Principal name

HYAL2 / Hyaluronidase-2 antibody

Alternative names for HYAL2 / Hyaluronidase-2 antibody

LUCA2, Hyal-2, Hyaluronoglucosaminidase-2, Lung carcinoma protein 2

SwissProt ID

O35632 (Mouse), Q12891 (Human), Q8SQG7 (Sheep), Q8SQG8 (Bovin), Q9Z2Q3 (Rat)

Gene ID

8692 (HYAL2), 286920 (Accn3)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Goat, Mouse

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of HYAL2 / Hyaluronidase-2 antibody

This gene encodes a protein which is similar in structure to hyaluronidases. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is thought to be involved in cell proliferation, migration and differentiation. Varying functions have been described for this protein. It has been described as a lysosomal hyaluronidase which is active at a pH below 4 and specifically hydrolyzes high molecular weight hyaluronan. It has also been described as a GPI-anchored cell surface protein which does not display hyaluronidase activity but does serve as a receptor for the oncogenic virus Jaagsiekte sheep retrovirus. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. This gene encodes two alternatively spliced transcript variants which differ only in the 5' UTR. [provided by RefSeq]. Transcript Variant: This variant (2) uses an alternate first exon in the 5' UTR. It encodes the same protein as transcript variant 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

Monzon, M.E., et al. J. Biol. Chem. 285(34):26126-26134(2010)
Tzuman, Y.C., et al. Neoplasia 12(1):51-60(2010)
de la Motte, C., et al. Am. J. Pathol. 174(6):2254-2264(2009)
Nykopp, T.K., et al. BMC Cancer 9, 143 (2009)
Miller, A.D., et al. Osteoarthr. Cartil. 14(12):1315-1317(2006)

10 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

HYAL2 / Hyaluronidase-2 (2-12) antibody

Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) Goat IgG Aff - Purified Eq, Fi, Hu, Mky, Prim P
50 µg / €470.00
  Acris Antibodies GmbH

HYAL2 / Hyaluronidase-2 (Center) antibody

Immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue reacted with HYAL2 / Hyaluronidase-2 Antibody (Center) Cat.-No AP52133PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining. Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

HYAL2 / Hyaluronidase-2 (C-term) antibody

Immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue reacted with HYAL2 Antibody (C-term) Cat.-No AP52134PU-N, which was peroxidase conjugated to the secondary antibody and followed by DAB staining. Rabbit Ig Aff - Purified Hu F, P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

HYAL2 / Hyaluronidase-2 antibody

HYAL2 / Hyaluronidase-2 Mouse Hu WB
50 µg / €370.00
  Abnova Taiwan Corp.

HYAL2 / Hyaluronidase-2 antibody

HYAL2 / Hyaluronidase-2 Rabbit IgG Aff - Purified Hu, Ms, Rt WB
0.1 mg / €290.00
  Boster Immunoleader

HYAL2 / Hyaluronidase-2 antibody

Immunohistochemistry-Paraffin: HYAL2 Antibody [NBP1-81283] - Immunohistochemical staining of human kidney shows strong cytoplasmic positivity in cells in tubules. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

HYAL2 / Hyaluronidase-2

HYAL2 / Hyaluronidase-2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

HYAL2 / Hyaluronidase-2

HYAL2 / Hyaluronidase-2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates (Overexpressed)

Catalog No.    

HYAL2 overexpression lysate

HYAL2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

HYAL2 overexpression lysate

HYAL2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

10 Item(s)

per page
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