HYAL2 / Hyaluronidase-2 antibody

Principal name

HYAL2 / Hyaluronidase-2 antibody

Alternative names for HYAL2 / Hyaluronidase-2 antibody

LUCA2, Hyal-2, Hyaluronoglucosaminidase-2, Lung carcinoma protein 2

SwissProt ID

O35632 (Mouse), Q12891 (Human), Q8SQG7 (Sheep), Q8SQG8 (Bovin), Q9Z2Q3 (Rat)

Gene ID

8692 (HYAL2), 15587 (Hyal2)

Available reactivities

Eq (Equine), Fi (Fish), Hu (Human), Mky (Monkey), Prim (Primate), Ms (Mouse), Rt (Rat)

Available hosts

Goat, Rabbit, Mouse

Available applications

Paraffin Sections (P), Western blot / Immunoblot (WB), Flow Cytometry (F)

Background of HYAL2 / Hyaluronidase-2 antibody

HYAL2(hyaluronoglucosaminidase 2) also known as hyaluronidase 2, LuCa-2, is an enzyme that in humans is encoded by the HYAL2 gene. HYAL2 cDNAs encode a preprotein with an N-terminal signal peptide. Northern blot analysis indicated that HYAL2 was expressed in all human tissues tested except adult brain, and Western blot analysis detected Hyal2protein in all mouse tissues examined except adult brain. The HYAL2 gene is mapped on 3p21.31. HYAL2 is a glycosylphosphatidylinositol (GPI)-anchored protein on the cell surface and serves as a receptor for entry into the cell of the jaagsiekte sheep retrovirus (JSRV). The findings of Rai et al. (2001) that HYAL2 is a GPI-anchored protein on the cell surface showed that GFP would likely be cleaved from HYAL2 during GPI addition, leaving HYAL2 on the cell surface and resulting in GFP transit to the lysosome for degradation.

General readings

Monzon, M.E., et al. J. Biol. Chem. 285(34):26126-26134(2010)
Tzuman, Y.C., et al. Neoplasia 12(1):51-60(2010)
de la Motte, C., et al. Am. J. Pathol. 174(6):2254-2264(2009)
Nykopp, T.K., et al. BMC Cancer 9, 143 (2009)
Miller, A.D., et al. Osteoarthr. Cartil. 14(12):1315-1317(2006)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

HYAL2 / Hyaluronidase-2 (2-12) antibody

Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) Goat IgG Aff - Purified Hu P
50 µg / €470.00
  Acris Antibodies GmbH

HYAL2 / Hyaluronidase-2 (Center) antibody

Immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue reacted with HYAL2 / Hyaluronidase-2 Antibody (Center) Cat.-No AP52133PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining. Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

HYAL2 / Hyaluronidase-2 (C-term) antibody

Immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue reacted with HYAL2 Antibody (C-term) Cat.-No AP52134PU-N, which was peroxidase conjugated to the secondary antibody and followed by DAB staining. Rabbit Ig Aff - Purified Hu F, P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

Hyal2 - mouse gene knockout kit via CRISPR

Hyal2 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Hyal2 - mouse gene knockout kit via CRISPR

Hyal2 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Hyal2 - mouse gene knockout kit via CRISPR

Hyal2 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Hyal2 - mouse gene knockout kit via CRISPR

Hyal2 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

HYAL2 overexpression lysate

HYAL2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

HYAL2 overexpression lysate

HYAL2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, HYAL2 (mGFP-tagged) - Human hyaluronoglucosaminidase 2 (HYAL2), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, HYAL2 (mGFP-tagged) - Human hyaluronoglucosaminidase 2 (HYAL2), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, HYAL2 (Myc-DDK tagged) - Human hyaluronoglucosaminidase 2 (HYAL2), transcript variant 1 , 200 uL, >10^7 TU/mL

Lenti ORF particles, HYAL2 (Myc-DDK tagged) - Human hyaluronoglucosaminidase 2 (HYAL2), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Lenti ORF particles, HYAL2 (Myc-DDK tagged) - Human hyaluronoglucosaminidase 2 (HYAL2), transcript variant 2 , 200 uL, >10^7 TU/mL

Lenti ORF particles, HYAL2 (Myc-DDK tagged) - Human hyaluronoglucosaminidase 2 (HYAL2), transcript variant 2 , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

12 Item(s)

per page
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