IAP2 / BIRC2 antibody

Principal name

IAP2 / BIRC2 antibody

Alternative names for IAP2 / BIRC2 antibody

API1, MIHB, RNF48, Inhibitor of apoptosis protein 2, C-IAP1, cIAP1, IAP homolog B, HIAP2, HIAP-2, Baculoviral IAP repeat-containing protein 2, TNFR2-TRAF-signaling complex protein 2, RING finger protein 48

SwissProt ID

Q13490 (Human), Q62210 (Mouse)

Gene ID

329 (BIRC2), 11797 (Birc2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C), Immunoprecipitation (IP), ELISA (detection) (E(detection)), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of IAP2 / BIRC2 antibody

Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and can be prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family that binds to and inhibits cell death proteases. The two isoforms of c-IAP (c-IAP1 and c-IAP2) are structurally related to XIAP, containing 3 baculoviral IAP repeat (BIR) motifs that are essential and sufficient for the binding and inhibition of caspases -3, -7. The c-IAPs can associate with the death receptor TNF-R2, and mediate the ubiquitinization of TRAF2 following the binding of TNF-a by its receptor. Omi, a negative regulator of c-IAP, inhibits its activity by catalytically cleaving c-IAP. Another negative regulator, Smac/DIABLO, acts by enhancing the auto-ubiquitization activity of c-IAP.

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  2. Highly Validated (2)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

IAP2 / BIRC2 antibody

  Rabbit Polyclonal cIAP1 Antibody  
Immunohistochemical staining of human adrenal gland shows strong nuclear and cytoplasmic positivity in cortical cells.This validation was performed by Protein Atlas and the presentation of data is for informational purposes only. Rabbit IgG Purified Hu E, ICC/IF, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

IAP2 / BIRC2 (361-372) antibody

Formalin-Fixed, Paraffin-Embedded Human Adrenal stained with IAP2 / BIRC2 antibody Cat.-No AP08427PU-N at 1/250 dilution after heat-induced antigen retrieval. Rabbit IgG Serum Hu P, WB
50 µl / €470.00
  Acris Antibodies GmbH

IAP2 / BIRC2 (C-term) antibody

  Rabbit Polyclonal cIAP Antibody  
Western blot analysis of c-IAP in human lung lysate with c-IAP antibody at 1 (lane A), 2 (lane B), and 4 (lane C) ug/ml, respectively. Rabbit IgG Aff - Purified Hu, Ms E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

IAP2 / BIRC2 antibody

  Anti-BIRC2 Rabbit Polyclonal Antibody  
Predicted band size: 70 kDa . Positive control: Human fetal muscle tissue lysate. Recommended dilution: 1/200-1000. (Gel: 8%SDS-PAGE Lysate: 40 ug per lane Primary antibody: 1/300 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 2 minutes) Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

IAP2 / BIRC2 antibody

  Anti-BIRC2 rabbit polyclonal antibody  
Predicted band size: 70kDa. Positive control: SKOV3 cell lysate. Recommended dilution: 1/500-2000. (Gel: 8%SDS-PAGE Lysate:40 ug Primary antibody: 1/300 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/8000 dilution Exposure time: 30 seconds) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

IAP2 / BIRC2 antibody

  Rabbit anti-BIRC2 Polyclonal Antibody  
Western blot analysis of extracts from HeLa cells, treated with Adriamycin (0.5ug/ml, 24hours), using RFA2 (Phospho-Thr21) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

IAP2 / BIRC2 antibody

Western blot analysis of cIAP-1 in Jurkat cell lysate. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 mg / €350.00
  Acris Antibodies GmbH

IAP2 / BIRC2 control peptide

IAP2 / BIRC2 Purified
50 µg / €180.00
  Acris Antibodies GmbH

IAP2 / BIRC2 antibody

Western blot analysis of cIAP-2 in Jurkat Cell Lysate. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 mg / €330.00
  Acris Antibodies GmbH

IAP2 / BIRC2 antibody

Prostate: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit Aff - Purified Hu, Ms ICC/IF, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

Birc2 - mouse gene knockout kit via CRISPR

Birc2 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Birc2 - mouse gene knockout kit via CRISPR

Birc2 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Birc2 - mouse gene knockout kit via CRISPR

Birc2 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Birc2 - mouse gene knockout kit via CRISPR

Birc2 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

IAP2 / BIRC2

  Recombinant protein of human baculoviral IAP repeat-containing 2 (BIRC2)  
IAP2 / BIRC2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

BIRC2 overexpression lysate

BIRC2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, BIRC2 (mGFP-tagged) - Human baculoviral IAP repeat containing 2 (BIRC2), 200 uL, >10^7 TU/mL

Lenti ORF particles, BIRC2 (mGFP-tagged) - Human baculoviral IAP repeat containing 2 (BIRC2), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, BIRC2 (Myc-DDK tagged) - Human baculoviral IAP repeat containing 2 (BIRC2) , 200 uL, >10^7 TU/mL

Lenti ORF particles, BIRC2 (Myc-DDK tagged) - Human baculoviral IAP repeat containing 2 (BIRC2) , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Birc2 (GFP-tagged) - Mouse baculoviral IAP repeat-containing 2 (Birc2), 200 uL, >10^7 TU/mL

Lenti ORF particles, Birc2 (GFP-tagged) - Mouse baculoviral IAP repeat-containing 2 (Birc2), 200 uL, >10^7 TU/mL  
200 µl / €1,270.00
  OriGene Technologies, Inc.

Lenti ORF particles, Birc2 (Myc-DDK-tagged) - Mouse baculoviral IAP repeat-containing 2 (Birc2), 200 uL, >10^7 TU/mL

Lenti ORF particles, Birc2 (Myc-DDK-tagged) - Mouse baculoviral IAP repeat-containing 2 (Birc2), 200 uL, >10^7 TU/mL  
200 µl / €1,140.00
  OriGene Technologies, Inc.

20 Item(s)

per page
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