ICT1 / DS1 antibody

Principal name

ICT1 / DS1 antibody

Alternative names for ICT1 / DS1 antibody

Digestion substraction 1, DS-1, Immature colon carcinoma transcript 1 protein

SwissProt ID

Q14197 (Human), Q3T116 (Bovin), Q8R035 (Mouse)

Gene ID

3396 (ICT1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), ELISA (detection) (E(detection)), Paraffin Sections (P)

Background of ICT1 / DS1 antibody

Peptidyl-tRNA hydrolase ICT1 acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. The adult colon epithelium contains 3 differentiated cell types that arise from a multipotent stem cell. Deviation from the normal maturation pathway by neoplastic transformation is thought to initiate in stem cells or their early descendants. This neoplastic-induced deviation is marked by a change in expression of several mRNAs. ICT1 is a member of the prokaryotic/mitochondrial release factor family whose expression is downregulated over 4 fold upon colon stem cell differentiation. This downregulation of ICT1 could lead to its use as a marker for detection of colon carcinomas.

General readings

Richer, R, et al. (2010) EMBO J 17;29(6): 1116-25.
van Belzen, N., et al. (1995) Eur J Biochem 15;234(3):843-8.

20 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ICT1 / DS1 antibody

ICT1 Antibody (C-term) (Cat. #TA325136) western blot analysis in Hela,Jurkat,U251,MDA-MB453,NCI-H292,K562,ZR-75-1 cell line lysates (35ug/lane).This demonstrates the ICT1 antibody detected the ICT1 protein (arrow). Rabbit IgG RB42881 Purified Hu WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

ICT1 / DS1 antibody

WB Suggested Anti-ICT1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: Human Thymus Rabbit IgG Purified Can, Eq, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

ICT1 / DS1 antibody

Immunohistochemical staining of paraffin-embedded Human prostate tissue within the normal limits using anti-ICT1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA505881) Mouse IgG1 OTI2F9 Purified Hu P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

ICT1 / DS1 (30-206) antibody

Western blot analysis: The cell lysates (40ug) were resolved by SDS - PAGE, transferred to PVDF membrane and probed with anti human ICT1 antibody (1:1000). Proteins were visualized using a goat anti mouse secondary antibody conjugated to HRP and an ECL detection system. Mouse IgG1 AT1E9 Purified Hu E, F, WB
0.1 ml / €310.00
  Acris Antibodies GmbH

ICT1 / DS1 (30-206) antibody

Western blot analysis: The cell lysates (40ug) were resolved by SDS - PAGE, transferred to PVDF membrane and probed with anti human ICT1 antibody (1:1000). Proteins were visualized using a goat anti mouse secondary antibody conjugated to HRP and an ECL detection system. Mouse IgG1 AT1E9 Purified Hu E, F, WB
50 µl / €220.00
  Acris Antibodies GmbH

ICT1 / DS1 antibody

ICT1 / DS1 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

ICT1 / DS1 antibody

Immunofluorescence of purified MaxPab antibody to ICT1 on HeLa cell. [antibody concentration 10 ug/ml] Mouse Purified Hu E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

ICT1 / DS1 antibody

Western Blot analysis of ICT1 expression in transfected 293T cell line (H00003396-T01) by ICT1 MaxPab polyclonal antibody.

Lane 1: ICT1 transfected lysate(23.60 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

ICT1 / DS1 antibody

ICT1 monoclonal antibody (M05), clone 6F8. Western Blot analysis of ICT1 expression in HeLa(Cat # L013V1 ). Mouse IgG1 6F8 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

ICT1 / DS1 antibody

ICT1 / DS1 Mouse IgG2a 4C10 Purified Hu E
0.1 mg / €370.00
  Abnova Taiwan Corp.

ICT1 / DS1 antibody

Human Thymus; WB Suggested Anti-ICT1 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: Human Thymus; ICT1 antibody - middle region (ARP54583_P050) in Human Thymus cells using Western Blot Rabbit Aff - Purified Bov, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

ICT1 / DS1 antibody

Western Blot: ICT Antibody [NBP1-55014] - This Anti-ICT1 antibody was used in Western Blot of Fetal thymus tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu, Ms, Rt WB
50 µg / €440.00
  Novus Biologicals Inc.

ICT1 / DS1 antibody

Immunohistochemistry-Paraffin: ICT Antibody [NBP1-87963] - Immunohistochemical staining of human rectum shows cytoplasmic positivity in glandular cells. Rabbit IgG Aff - Purified Hu, Rt P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

ICT1 / DS1

ICT1 / DS1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

ICT1 / DS1 (30-206, His-tag)

ICT1 / DS1 Human Purified > 90 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

ICT1 / DS1 (30-206, His-tag)

ICT1 / DS1 Human Purified > 90 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

ICT1 / DS1

ICT1 / DS1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

ICT1 / DS1

ICT1 / DS1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

ICT1 293T Cell Transient Overexpression Lysate(Denatured)

ICT1 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

ICT1 overexpression lysate

ICT1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

20 Item(s)

per page
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