IDS / SIDS antibody

Principal name

IDS / SIDS antibody

Alternative names for IDS / SIDS antibody

Iduronate 2-sulfatase, Idursulfase, Alpha-L-iduronate sulfate sulfatase

SwissProt ID

P22304 (Human), Q08890 (Mouse)

Gene ID

3423 (IDS)

Available reactivities

Hu (Human), Ms (Mouse), Can (Canine), Mky (Monkey), Rt (Rat), Bov (Bovine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunoprecipitation (IP), Paraffin Sections (P), Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of IDS / SIDS antibody

IDS(Iduronate-2-sulfatase) is a sulfatase enzyme associated with Hunter syndrome. Iduronate 2-sulfatase is involved in the lysosomal degradation of the glycosaminoglycans heparan sulfate and dermatan sulfate. Wilson et al. (1991) used an IDS cDNA clone to localize the gene to Xq28, distal to the fragile X site. Faust et al. (1992) and Daniele et al. (1993) demonstrated that the homologous Ids gene in the mouse occupies the same position on the X chromosome in relation to the FMR1, F9, and GABRA3 genes. Iduronate-2-sulfatase is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this X-chromosome gene that result in enzymatic deficiency lead to the sex-linked mucopolysaccharidosis type II, also known as Hunter syndrome. Iduronate-2-sulfatase has a strong sequence homology with human arylsulfatases A, B, and C, and human glucosamine-6-sulfatase.

General readings

Keeratichamroen S, Ketudat Cairns JR, Wattanasirichaigoon D, Wasant P, Ngiwsara L, Suwannarat P, Pangkanon S, Kuptanon J, Tanpaiboon P, Rujirawat T, Liammongkolkul S, Svasti J Molecular analysis of the iduronate-2-sulfatase gene in Thai patients with Hunter syndrome. J Inherit Metab Dis. 2008 May 20. [Epub ahead of print]. PMID: 18500569

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

IDS / SIDS antibody

  IDS (Iduronate 2 sulfatase) mouse monoclonal antibody, clone OTI1D9 (formerly 1D9)  
Immunohistochemical staining of paraffin-embedded Carcinoma of Human liver tissue using anti-IDS mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504257) Mouse IgG2a OTI1D9 Purified Hu, Ms F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

IDS / SIDS antibody

  IDS (Iduronate 2 sulfatase) mouse monoclonal antibody, clone OTI3B10 (formerly 3B10)  
Immunohistochemical staining of paraffin-embedded Human endometrium tissue within the normal limits using anti-IDS mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504276) Mouse IgG2a OTI3B10 Purified Hu F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

IDS / SIDS antibody

  IDS (Iduronate 2 sulfatase) mouse monoclonal antibody, clone OTI4G2 (formerly 4G2)  
Immunohistochemical staining of paraffin-embedded Human liver tissue within the normal limits using anti-IDS mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504277) Mouse IgG2a OTI4G2 Purified Can, Hu, Mky, Ms, Rt F, ICC/IF, P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

IDS / SIDS antibody

  Goat Anti-IDS Antibody  
TA305799 (0.1ug/ml) staining of Human Liver lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

IDS / SIDS antibody

  Rabbit Polyclonal Anti-IDS Antibody  
WB Suggested Anti-IDS Antibody; Titration: 1.0 ug/ml; Positive Control: Hela Whole Cell Rabbit IgG Purified Bov, Can, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

IDS / SIDS (transcript variant 1)

  Recombinant protein of human iduronate 2-sulfatase (IDS), transcript variant 1  
IDS / SIDS Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

IDS overexpression lysate

IDS overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

IDS overexpression lysate

IDS overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, IDS (mGFP-tagged) - Human iduronate 2-sulfatase (IDS), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, IDS (mGFP-tagged) - Human iduronate 2-sulfatase (IDS), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €920.00
  OriGene Technologies, Inc.

Lenti ORF particles, IDS (Myc-DDK tagged) - Human iduronate 2-sulfatase (IDS), transcript variant 2 , 200 uL, >10^7 TU/mL

Lenti ORF particles, IDS (Myc-DDK tagged) - Human iduronate 2-sulfatase (IDS), transcript variant 2 , 200 uL, >10^7 TU/mL  
200 µl / €820.00
  OriGene Technologies, Inc.

10 Item(s)

per page
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