IER3 / IEX1 antibody

Principal name

IER3 / IEX1 antibody

Alternative names for IER3 / IEX1 antibody

DIF2, IEX-1, PRG1, GLY96, Radiation-inducible immediate-early gene IEX-1, Immediate early protein GLY96, Immediate early response 3 protein, PACAP-responsive gene 1 protein, Differentiation-dependent gene 2 protein

SwissProt ID

P46694 (Mouse), P46695 (Human)

Gene ID

8870 (IER3)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F)

Background of IER3 / IEX1 antibody

IEX-1 is a stress inducible gene that is induced by ionizing radiation, ultraviolet radiation, and a variety of growth factors, i.e., FAS and TNF-alpha. IEX-1 is widely expressed in epithelial and endocrine tissues, as well as in vascular endothelium. It plays an important role in the regulation of cellular growth, cell death and oncogenesis. IEX-1 is precisely regulated by multiple transcription factors such as p53, NF-kappaB/rel, Sp1 and c-Myc, to ensure rapid and transient expression of IEX-1 in cells under a variety of stress conditions. IEX-1 is expressed as both a longer form (IEX1L) and a splice variant, designated IEX1S. It is localized to the nucleus and perinuclear region. Overexpression of IEX-1 facilitates apoptosis and cell cycle progression, whereas disruption of IEX-1 expression is associated with decreases in both apoptosis and cell cycle progression.

General readings

Shahid, M., et al. Hypertension 56(4):705-712(2010)
Ucisik-Akkaya, E., et al. Mol. Hum. Reprod. 16(10):770-777(2010)
Fellay, J., et al. PLoS Genet. 5 (12), E1000791 (2009)
Do, T.N., et al. Cancer Genet. Cytogenet. 195(1):31-36(2009)
Barcellos, L.F., et al. PLoS Genet. 5 (10), E1000696 (2009)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

IER3 / IEX1 (N-term) antibody

Immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue reacted with IER3 / IEX1 Antibody (N-term) Cat.-No AP52148PU-N, which was peroxidase conjugated to the secondary antibody and followed by AB staining. Rabbit Ig Aff - Purified Hu, Ms F, ICC/IF, P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

IER3 / IEX1 antibody

Western blot analysis of IEX1 in human brain tissue lysate with IEX1 antibody at (A) 2 and (B) 4 ug/ml. Rabbit IgG Aff - Purified Hu, Ms E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

IER3 / IEX1 antibody

AP07307PU-N IER3 Antibody Staining of Formalin-Fixed Paraffin-Embedded Human Adrenal at 5 µg/ml followed by biotinylated goat anti-Rabbit IgG secondary antibody, Alkaline Phosphatase-Streptavidin and Chromogen. Rabbit IgG Aff - Purified Hu, Ms P, WB
50 µg / €470.00
  Acris Antibodies GmbH

IER3 / IEX1 Control Peptide

IER3 / IEX1
50 µg / €160.00
  Acris Antibodies GmbH

IER3 / IEX1 antibody

Immunohistochemistry of IER3 in human liver tissue with IER3 polyclonal antibody ( Cat # PAB13000 ) at 2.5 µg/ml. Rabbit Hu, Ms P, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

IER3 / IEX1 antibody

IER3 / IEX1 Rabbit Aff - Purified Hu, Ms P, WB
50 µg / €480.00
  Novus Biologicals Inc.

IER3 / IEX1 antibody

Immunohistochemistry-Paraffin: IER3 Antibody [NBP1-76802] - Human liver tissue with IEX-1 antibody at 2.5 ug/mL._x000d_ Rabbit Aff - Purified Hu, Ms E, P, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

IER3 / IEX1 (1-82, His-tag)

IER3 / IEX1 Human Purified > 85 % by SDS - PAGE E. coli
0.1 mg / €730.00
  Acris Antibodies GmbH

IER3 / IEX1 (1-82, His-tag)

IER3 / IEX1 Human Purified > 85 % by SDS - PAGE E. coli
20 µg / €300.00
  Acris Antibodies GmbH

IER3 / IEX1

IER3 / IEX1 Human
2 µg / €300.00
  Abnova Taiwan Corp.

IER3 / IEX1

IER3 / IEX1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

IER3 / IEX1

IER3 / IEX1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

IER3 / IEX1

IER3 / IEX1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

IER3 / IEX1

IER3 / IEX1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

IER3 overexpression lysate

IER3 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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