IFNA1 / Interferon-alpha 1 antibody

Principal name

IFNA1 / Interferon-alpha 1 antibody

Alternative names for IFNA1 / Interferon-alpha 1 antibody

IFNA13, Interferon alpha-D, LeIF D, IFN-alpha 1

SwissProt ID

P01562 (Human), P01572 (Mouse), P05003 (Horse), P05011 (Rat), P07348 (Bovin), P42165 (Chick), P49879 (Pig), P81255 (Canfa)

Gene ID

3439 (IFNA1), 298210 (Ifna1), 15962, 3447 (IFNA13)

Available reactivities

Hu (Human), Por (Porcine), Bov (Bovine), Ms (Mouse), Mky (Monkey), Rt (Rat), Can (Canine), Gt (Goat), Sh (Sheep)

Available hosts

Mouse, Rabbit, Rat

Available applications

Frozen Sections (C), Enzyme Immunoassay (E), Functional assay (FN), Immunoprecipitation (IP), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), EPair for Elisa (EPair), Flow Cytometry (F)

Background of IFNA1 / Interferon-alpha 1 antibody

The type I interferons consist of 14 different alpha isoforms (subtypes with slightly different specificities), and single beta, omega, epsilon and kappa isoforms. Homologous molecules are found in many species, including rats and mice (and most mammals), and have been identified in birds, reptiles and fish species. Interferon alpha is produced primarily by plasmacytoid dendritic cells and is a potent component of the anti viral innate immune response; it modulates adaptive immunity.
The classification of mammalian cytokines with antiviral activity, is well documented as being either Type I Interferon (IFNI) or Type II Interferon (IFNII). This is not the case for avian IFNs however, even though IFN was first detected in the chicken. A growing number of functional studies indicate similarities between chicken IFN and mammalian IFNI, revealing the conservation of cysteine residues and the existence of around ten closely related intron-less IFN alpha genes. Further research has shown that chIFN-alpha genes are strongly expressed following viral infection of monocyte-derived macrophage and embryo fibroblasts and that recombinant chicken IFN acts as a potent antiviral agent.

General readings

Kontsek, P. et al. Immunodominant structures in the aminotermonal portion of human interferon alpha 1. Mol Immunol. 29: 863-870 (1992)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

IFNA1 / Interferon-alpha 1 antibody

  Rabbit Polyclonal Anti-IFNA13 Antibody  
WB Suggested Anti-IFNA13 Antibody; Titration: 1.0 ug/ml; Positive Control: Placenta Rabbit IgG Purified Bov, Can, Gt, Hu, Por, Sh WB
50 µg / €325.00
  OriGene Technologies, Inc.

IFNA1 / Interferon-alpha 1 antibody

  Mouse monoclonal Anti-Interferon Clone ST126  
IFNA1 / Interferon-alpha 1 Mouse IgG1 ST126 Purified Hu
0.1 mg / €325.00
  OriGene Technologies, Inc.

IFNA1 / Interferon-alpha 1 antibody

  Mouse monoclonal Anti-Interferon Clone ST225  
IFNA1 / Interferon-alpha 1 Mouse IgG1 ST225 Purified Hu
0.1 mg / €325.00
  OriGene Technologies, Inc.

IFNA1 / Interferon-alpha 1 antibody

  Mouse monoclonal Anti-Interferon Clone ST254  
IFNA1 / Interferon-alpha 1 Mouse IgG1 ST254 Purified Hu
0.1 mg / €325.00
  OriGene Technologies, Inc.

IFNA1 / Interferon-alpha 1 antibody

  Mouse monoclonal Anti-Interferon Clone ST47  
IFNA1 / Interferon-alpha 1 Mouse IgM ST47 Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

IFNA1 / Interferon-alpha 1 antibody

  Rabbit Polyclonal Interferon alpha-D Antibody  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY IFNA1 (RC210902, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-IFNA1. Rabbit IgG Purified Hu E, WB
50 µg / €325.00
  OriGene Technologies, Inc.

IFNA1 / Interferon-alpha 1 antibody

IFNA1 / Interferon-alpha 1 Mouse IgG1 2-52 Purified Hu C, E, WB
0.1 mg / €310.00
  Acris Antibodies GmbH

IFNA1 / Interferon-alpha 1 antibody

IFNA1 / Interferon-alpha 1 Mouse IgG1 2-48 Purified Hu C, E, WB
0.1 mg / €310.00
  Acris Antibodies GmbH

IFNA1 / Interferon-alpha 1 antibody

IFNA1 / Interferon-alpha 1 Rabbit Serum Bov WB
0.1 ml / €380.00
  Acris Antibodies GmbH

IFNA1 / Interferon-alpha 1 antibody

IFNA1 / Interferon-alpha 1 Rabbit Serum Bov WB
20 µl / €150.00
  Acris Antibodies GmbH

IFNA1 / Interferon-alpha 1 antibody

IFNA1 / Interferon-alpha 1 Rat IgG1 F18 Purified Ms E, F, FN
0.1 mg / €310.00
  Acris Antibodies GmbH

IFNA1 / Interferon-alpha 1 antibody

IFNA1 / Interferon-alpha 1 Mouse IgG1 G16 Azide Free Por E, FN, IP
0.25 mg / €610.00
  Acris Antibodies GmbH

IFNA1 / Interferon-alpha 1 antibody

IFNA1 / Interferon-alpha 1 Mouse IgG1 MMHA-6 Purified Hu C, E, FN, IP, WB
50 µg / €270.00
  PBL Assay Science

IFNA1 / Interferon-alpha 1 antibody

IFNA1 / Interferon-alpha 1 Mouse IgG1 MMHA-9 Purified Hu C, E, FN, IP, WB
50 µg / €270.00
  PBL Assay Science

IFNA1 / Interferon-alpha 1 antibody

IFNA1 / Interferon-alpha 1 Mouse IgG1 MMHA-14 Purified Hu C, E, FN, IP, WB
50 µg / €270.00
  PBL Assay Science

CRISPR

Catalog No. Species Donor Vector  

IFNA1 - human gene knockout kit via CRISPR

IFNA1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

IFNA1 - human gene knockout kit via CRISPR

IFNA1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

IFNA1 - human gene knockout kit via CRISPR

IFNA1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Ifna1 - mouse gene knockout kit via CRISPR

Ifna1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Ifna1 - mouse gene knockout kit via CRISPR

Ifna1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

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