IFNAR1 antibody

Principal name

IFNAR1 antibody

Alternative names for IFNAR1 antibody

IFN-R-1, IFN-alpha Receptor alpha, IFN-alpha/beta receptor 1, Type I interferon receptor 1, CRF2-1, Interferon-alpha/beta receptor alpha chain, Cytokine receptor class-II member 1, Cytokine receptor family 2 member 1

SwissProt ID

P17181 (Human), P33896 (Mouse), Q04790 (Bovin), Q28589 (Sheep), Q764M8 (Pig)

Gene ID

3454 (IFNAR1)

Available reactivities

Rt (Rat), Hu (Human), Ms (Mouse), Bov (Bovine), Sh (Sheep), Can (Canine)

Available hosts

Rabbit, Mouse, Goat

Available applications

Frozen Sections (C), Paraffin Sections (P), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Flow Cytometry (F), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF), ELISA (detection) (E(detection))

Background of IFNAR1 antibody

IFNAR1 is a member of the cytokine receptor superfamily which also includes receptors for interleukins, IFN gamma, ciliary neurotrophic factor, somatotrophin, erythropoietin, nerve growth factor, tumor necrosis factor, leukemia inhibitory factor, and oncostatin M. Some members of the family have an alpha chain with either low or high ligand binding affinity and at least one beta chain involved in signal transduction with either relatively low or no ligand binding affinity. Type I interferons, alpha and beta, induce a variety of effects on target cells including antiviral, antiproliferative, and immunomodulatory activities. The alpha and beta interferons compete to bind to a common cell surface receptor, while IFN gamma binds to a distinct receptor. IFNAR1 is very responsive to type I interferons and bind to IFN beta and IFN alpha subtypes. It is also functionally involved in signal transduction because of its association with the cytoplasmic tyrosine kinase JAK1. The type I interferons, alpha and beta, are produced by leukocytes (alpha subunits), fibroblasts (beta subtypes), lymphocytes (omega subtypes), and ruminant embryos (tau subtypes). Interferon receptors are generally found on most human cell types whatever their origin, even on cells poorly responsive to interferon. IFNAR1 is expressed on the cell surface in a variety of human cell lines.

General readings

1. Kotenko SV, et al Nat Acad Sci USA,
96:5007-5012, 1999.
2. Constantinescu SN, et al Proc Natl Acad Sci USA
91:9602-9606, 1994.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

IFNAR1 pSer535/539 antibody

Figure 1. Western blot of immunoprecipitates from HEK 293 cells transfected with: 1. Mock, 2. IFNAR1 WT, and 3. IFNAR1 S535A and S539A mutants showing specific immunolabeling of the ~110k to ~130k IFNAR1 WT. The immunolabeling is absent in IFNAR1 Ser535 and Ser539 mutants (Control). The immunolabeling is blocked by the phosphopeptide (Phos) used as the antigen but not by the corresponding dephosphopeptide (Dephos). Rabbit IgG Aff - Purified Bov, Can, Hu, Ms, non-Human Primates, Rt, Sh C, WB
0.1 ml / €380.00
  Acris Antibodies GmbH

IFNAR1 (353-364) antibody

Staining of K562 lysate using IFNAR1 Antibody Cat.-No AP32812PU-N at 0.3 µg/ml (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu E, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

IFNAR1 (181-193) antibody

Staining of HepG2 lysate using IFNAR1 Antibody Cat.-No AP32813PU-N at 0.3 µg/ml (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu E, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

IFNAR1 antibody

interferon alpha Receptor 1 antibody [N1N3] detects interferon alpha Receptor 1 protein by western blot analysis. A.50 ug mouse brain lysate/extract. 7.5 % SDS-PAGE. interferon alpha Receptor 1 antibody [N1N3] (TA308908) dilution: 1:1000 Rabbit IgG Aff - Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

IFNAR1 antibody

Western blot analysis of extracts of various cell lines, using IFNAR1 antibody. Rabbit IgG Purified Hu
0.1 mg / €325.00
  OriGene Technologies, Inc.

IFNAR1 antibody

ELISA: IFNAR1 Antibody Rabbit IgG Purified Hu E
0.1 mg / €325.00
  OriGene Technologies, Inc.

IFNAR1 antibody

Immunohistochemistry (IHC) analyzes of IFN-α/βRα antibody (Cat.-No.: AP06615PU-N) in paraffin-embedded human brain tissue. Rabbit Aff - Purified Hu, Ms ICC/IF, P
0.1 mg / €350.00
  Acris Antibodies GmbH

IFNAR1 antibody

Western blot analysis of IFNAR1 Antibody (Center) (AP18064PU-N) in K562 cell line lysates (35ug/lane). IFNAR1 (arrow) was detected using the purified Pab.(8ug/ml) Rabbit Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

IFNAR1 antibody

Western Blot analysis of IFNAR1 expression in transfected 293T cell line (H00003454-T01) by IFNAR1 MaxPab polyclonal antibody.

Lane 1: IFNAR1 transfected lysate(61.27 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

IFNAR1 antibody

Western Blot analysis of IFNAR1 expression in transfected 293T cell line (H00003454-T02) by IFNAR1 MaxPab polyclonal antibody.

Lane 1: IFNAR1 transfected lysate(63.50 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

IFNAR1 antibody

IFNAR1 Mouse IgG2a 1H2 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

IFNAR1 antibody

Western blot of immunoprecipitates from HEK 293 cells transfected with 1. Mock, 2. IFNAR1 WT, and 3. IFNAR1 S535A and S539A mutants showing specific immunolabeling of the ~110k to ~130k IFNAR1 WT. The immunolabeling is absent in IFNAR1 Ser535 and Ser539 mutants (Control). The immunolabeling is blocked by the phosphopeptide (Phos) used as the antigen but not by the corresponding dephosphopeptide (Dephos). Rabbit Bov, Hu, Ms, Rt, Sh C, IP, WB
0.1 ml / €510.00
  Abnova Taiwan Corp.

IFNAR1 pTyr466 antibody

Immunohistochemistry analysis of paraffin-embedded human brain, using Interferon-alpha/beta Receptor alpha (Phospho-Tyr466) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, P
50 µg / €205.00
  Assay Biotech

IFNAR1 pTyr466 antibody

Immunohistochemistry analysis of paraffin-embedded human brain, using Interferon-alpha/beta Receptor alpha (Phospho-Tyr466) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, P
0.1 mg / €310.00
  Assay Biotech

IFNAR1 antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using Interferon-alpha/beta Receptor alpha chain (Ab-466) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, ICC/IF, P
50 µg / €205.00
  Assay Biotech

IFNAR1 antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using Interferon-alpha/beta Receptor alpha chain (Ab-466) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, ICC/IF, P
0.1 mg / €310.00
  Assay Biotech

IFNAR1 pTyr466 antibody

Western blot analysis of IFNAR1 (pY466) expression in K562 EGF-treated (A) whole cell lysates. Rabbit Aff - Purified Hu IP, WB
30 µl / €210.00
  Cohesion Biosciences Ltd.

IFNAR1 pTyr466 antibody

Western blot analysis of IFNAR1 (pY466) expression in K562 EGF-treated (A) whole cell lysates. Rabbit Aff - Purified Hu IP, WB
0.1 ml / €330.00
  Cohesion Biosciences Ltd.

IFNAR1 pTyr466 antibody

Western blot analysis of IFNAR1 (pY466) expression in K562 EGF-treated (A) whole cell lysates. Rabbit Aff - Purified Hu IP, WB
0.2 ml / €530.00
  Cohesion Biosciences Ltd.

IFNAR1 antibody

ELISA: IFNAR1 Antibody [33310002] Rabbit Hu E, WB
50 µg / €440.00
  Novus Biologicals Inc.

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