IKZF1 / IKAROS antibody

Principal name

IKZF1 / IKAROS antibody

Alternative names for IKZF1 / IKAROS antibody

IK1, LYF-1, LYF1, ZNFN1A1, DNA-binding protein Ikaros, Ikaros family zinc finger protein 1, Lymphoid transcription factor LyF-1

SwissProt ID

O42410 (Chick), Q03267 (Mouse), Q13422 (Human)

Gene ID

10320 (IKZF1)

Available reactivities

Bov (Bovine), Can (Canine), Hu (Human), Ms (Mouse), Por (Porcine), Rb (Rabbit), Rt (Rat), Chk (Chicken), African clawed frog, Eq (Equine), GP (Guinea Pig)

Available hosts

Rabbit, Goat, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Flow Cytometry (F), Enzyme Immunoassay (E), ELISA (detection) (E(detection))

Background of IKZF1 / IKAROS antibody

This gene encodes a transcription factor that belongs to the family of zinc-finger D-binding proteins associated with chromatin remodeling. The expression of this protein is restricted to the fetal and adult hemo-lymphopoietic system, and it functions as a regulator of lymphocyte differentiation. Several altertively spliced transcript variants encoding different isoforms have been described for this gene. Most isoforms share a common C-termil domain, which contains two zinc finger motifs that are required for hetero- or homo-dimerization, and for interactions with other proteins. The isoforms, however, differ in the number of N-termil zinc finger motifs that bind D and in nuclear localization sigl presence, resulting in members with and without D-binding properties. Only a few isoforms contain the requisite three or more N-termil zinc motifs that confer high affinity binding to a specific core D sequence element in the promoters of target genes. The non-D-binding isoforms are largely found in the cytoplasm, and are thought to function as domint-negative factors. Overexpression of some domint-negative isoforms have been associated with B-cell maligncies, such as acute lymphoblastic leukemia (ALL). [provided by RefSeq, May 2014].

General readings

Mullighan CG, Goorha S, Radtke I, Miller CB, Coustan-Smith E, Dalton JD, Girtman K, Mathew S, Ma J, Pounds SB, Su X, Pui CH, Relling MV, Evans WE, Shurtleff SA, Downing JR.
Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia.
Nature. 2007 Apr 12;446(7137):758-64.
PMID: 17344859

  1. Quick-Filters:
  2. Highly Validated (4)

17 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

IKZF1 / IKAROS antibody

  IKZF1 Rabbit Polyclonal Antibody  
Western blot analysis of extracts of various cell lines, using IKZF1 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

IKZF1 / IKAROS antibody

  Rabbit Polyclonal anti-IKZF1 antibody  
WB Suggested Anti-IKZF1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: Hela cell lysate Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

IKZF1 / IKAROS antibody

  Rabbit Monoclonal anti-IKAROS Antibody  
Human Tonsil stained with anti-IKAROS antibody. Rabbit IgG SP108 Purified Hu F, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

IKZF1 / IKAROS antibody

  Rabbit Polyclonal IKZF1 Antibody  
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-IKZF1 Rabbit Polyclonal antibody. (TA590587) Rabbit IgG Purified Hu E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

IKZF1 / IKAROS antibody

Staining of paraffin embedded Human Tonsil using IKAROS Antibody Cat.-No AP23703PU-N at 1 µg/ml. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. Goat Aff - Purified Bov, Can, Hu E, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

IKZF1 / IKAROS antibody

  Goat Polyclonal Antibody against IKZF1  
TA303248 (0.03µg/ml) staining of MOLT4 lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

IKZF1 / IKAROS antibody

  Rabbit Polyclonal Anti-ZNFN1A1 Antibody  
WB Suggested Anti-ZNFN1A1 Antibody Titration: 0.2-1 ug/ml; Positive Control: Daudi cell lysateIKZF1 is strongly supported by BioGPS gene expression data to be expressed in Human Daudi cells Rabbit IgG Purified Can, Hu P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

IKZF1 / IKAROS antibody

  Rabbit Polyclonal Anti-IKZF1 Antibody  
WB Suggested Anti-IKZF1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: ACHN cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

IKZF1 / IKAROS antibody

  Mouse Monoclonal Ikaros (C-terminus) Antibody  
Western blot detection of Ikaros(C-terminus) in Ramos and Jurkat cell lysates using Ikaros(C-terminus) mouse mAb (1:1000 diluted).Predicted band size: 58KDa.Observed band size: 58KDa. Mouse IgG1 1A12-F2-D8 Purified WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

IKZF1 / IKAROS antibody

  Rabbit Polyclonal anti-IKAROS Antibody  
Human Tonsil stained with anti-IKAROS antibody. Rabbit IgG Purified Hu P
0.1 ml / €325.00
  OriGene Technologies, Inc.

IKZF1 / IKAROS (C-term) antibody

Immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue using IKZF1/IKAROS antibody Cat.-No.AP52180PU-N (C-term), followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the IKZF1 antibody for IHC. Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu F, P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

IKZF1 - human gene knockout kit via CRISPR

IKZF1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

IKZF1 - human gene knockout kit via CRISPR

IKZF1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

IKZF1 - human gene knockout kit via CRISPR

IKZF1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

IKZF1 - human gene knockout kit via CRISPR

IKZF1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

IKZF1 / IKAROS

  Recombinant protein of human IKAROS family zinc finger 1 (Ikaros) (IKZF1)  
IKZF1 / IKAROS Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, IKZF1 (mGFP-tagged) - Human IKAROS family zinc finger 1 (Ikaros) (IKZF1), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, IKZF1 (mGFP-tagged) - Human IKAROS family zinc finger 1 (Ikaros) (IKZF1), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,140.00
  OriGene Technologies, Inc.

17 Item(s)

per page
  • LinkedIn