IKZF1 / IKAROS antibody

Principal name

IKZF1 / IKAROS antibody

Alternative names for IKZF1 / IKAROS antibody

IK1, LYF-1, LYF1, ZNFN1A1, DNA-binding protein Ikaros, Ikaros family zinc finger protein 1, Lymphoid transcription factor LyF-1

SwissProt ID

O42410 (Chick), Q03267 (Mouse), Q13422 (Human)

Gene ID

10320 (IKZF1)

Available reactivities

Bov (Bovine), Can (Canine), Hu (Human), Ms (Mouse), Por (Porcine), Rb (Rabbit), Rt (Rat), Chk (Chicken), African clawed frog, Eq (Equine), GP (Guinea Pig)

Available hosts

Rabbit, Goat, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Immunoprecipitation (IP), Flow Cytometry (F), ELISA (detection) (E(detection)), ChIP assay (ChIP)

Background of IKZF1 / IKAROS antibody

This gene encodes a transcription factor that belongs to the family of zinc-finger D-binding proteins associated with chromatin remodeling. The expression of this protein is restricted to the fetal and adult hemo-lymphopoietic system, and it functions as a regulator of lymphocyte differentiation. Several altertively spliced transcript variants encoding different isoforms have been described for this gene. Most isoforms share a common C-termil domain, which contains two zinc finger motifs that are required for hetero- or homo-dimerization, and for interactions with other proteins. The isoforms, however, differ in the number of N-termil zinc finger motifs that bind D and in nuclear localization sigl presence, resulting in members with and without D-binding properties. Only a few isoforms contain the requisite three or more N-termil zinc motifs that confer high affinity binding to a specific core D sequence element in the promoters of target genes. The non-D-binding isoforms are largely found in the cytoplasm, and are thought to function as domint-negative factors. Overexpression of some domint-negative isoforms have been associated with B-cell maligncies, such as acute lymphoblastic leukemia (ALL). [provided by RefSeq, May 2014].

General readings

Mullighan CG, Goorha S, Radtke I, Miller CB, Coustan-Smith E, Dalton JD, Girtman K, Mathew S, Ma J, Pounds SB, Su X, Pui CH, Relling MV, Evans WE, Shurtleff SA, Downing JR.
Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia.
Nature. 2007 Apr 12;446(7137):758-64.
PMID: 17344859

  1. Quick-Filters:
  2. Highly Validated (3)

Items 1 to 20 of 23 total

per page
Page:
  1. 1
  2. 2

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

IKZF1 / IKAROS antibody

Western blot analysis of extracts of various cell lines, using IKZF1 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

IKZF1 / IKAROS antibody

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-IKZF1 Rabbit Polyclonal antibody. (TA590587) Rabbit IgG Purified Hu E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

IKZF1 / IKAROS antibody

Hum. Adult Placenta; Host: Rabbit. Target Name: CHAD . Sample Tissue: Human Adult Placenta . Antibody Dilution: 1.0ug/ml.; IKZF1 antibody - middle region (ARP31470_P050) in Hum. Adult Placenta cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

IKZF1 / IKAROS (N-term) antibody

Human tonsil stained with anti-IKAROS Antibody Cat.-No AM20273PU (Clone SP108). Rabbit IgG SP108 Purified Hu F, P, WB
0.5 ml / €510.00
  Acris Antibodies GmbH

IKZF1 / IKAROS (N-term) antibody

Human tonsil stained with anti-IKAROS Antibody Cat.-No AM20273PU (Clone SP108). Rabbit IgG SP108 Purified Hu F, P, WB
1 ml / €730.00
  Acris Antibodies GmbH

IKZF1 / IKAROS (N-term) antibody

Human tonsil stained with anti-IKAROS Antibody Cat.-No AM20273PU (Clone SP108). Rabbit IgG SP108 Purified Hu F, P, WB
0.1 ml / €290.00
  Acris Antibodies GmbH

IKZF1 / IKAROS antibody

Staining of paraffin embedded Human Tonsil using IKAROS Antibody Cat.-No AP23703PU-N at 1 µg/ml. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. Goat Aff - Purified Bov, Can, Hu E, P, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

IKZF1 / IKAROS antibody

AP23793PU IKAROS antibody staining of Human Tonsil. Rabbit Purified Hu P
0.5 ml / €360.00
  Acris Antibodies GmbH

IKZF1 / IKAROS antibody

AP23793PU IKAROS antibody staining of Human Tonsil. Rabbit Purified Hu P
1 ml / €520.00
  Acris Antibodies GmbH

IKZF1 / IKAROS antibody

AP23793PU IKAROS antibody staining of Human Tonsil. Rabbit Purified P
0.1 ml / €190.00
  Acris Antibodies GmbH

IKZF1 / IKAROS antibody

TA303248 (0.03µg/ml) staining of MOLT4 lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

IKZF1 / IKAROS antibody

WB Suggested Anti-ZNFN1A1 Antibody Titration: 0.2-1 ug/ml; Positive Control: Daudi cell lysateIKZF1 is strongly supported by BioGPS gene expression data to be expressed in Human Daudi cells Rabbit IgG Purified Can, Hu P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

IKZF1 / IKAROS antibody

WB Suggested Anti-IKZF1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: ACHN cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

IKZF1 / IKAROS antibody

Western blot detection of Ikaros(C-terminus) in Ramos and Jurkat cell lysates using Ikaros(C-terminus) mouse mAb (1:1000 diluted).Predicted band size: 58KDa.Observed band size: 58KDa. Mouse IgG1 1A12-F2-D8 Purified WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

IKZF1 / IKAROS (C-term) antibody

Immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue using IKZF1/IKAROS antibody Cat.-No.AP52180PU-N (C-term), followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the IKZF1 antibody for IHC. Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu F, P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

IKZF1 / IKAROS antibody

IKZF1 / IKAROS Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

IKZF1 / IKAROS antibody

Human kidney; ZNFN1A1 antibody - middle region (ARP32757_P050) in Human kidney cells using Immunohistochemistry Rabbit Aff - Purified Bov, Can, Hu, Ms, Por, Rb, Rt P, WB
50 µg / €350.00
  AVIVA Systems Biology

IKZF1 / IKAROS antibody

Human ACHN; WB Suggested Anti-IKZF1 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: ACHN cell lysate; IKZF1 antibody - middle region (ARP32758_P050) in Human ACHN cells using Western Blot Rabbit Aff - Purified Bov, Can, Chk, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

IKZF1 / IKAROS antibody

ELISA: IKZF1 Antibody [23210002] - Affinity Purified Rabbit Hu E, P, WB
50 µg / €500.00
  Novus Biologicals Inc.

IKZF1 / IKAROS antibody

NBP1-00125 (0.03ug/ml) staining of MOLT4 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat IgG Aff - Purified Hu E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

Items 1 to 20 of 23 total

per page
Page:
  1. 1
  2. 2
  • LinkedIn