IMPDH2 antibody

Principal name

IMPDH2 antibody

Alternative names for IMPDH2 antibody

IMPD2, Inosine-5'-monophosphate dehydrogenase 2, IMP dehydrogenase 2, EC=1.1.1.205, IMPDH-II, IMPD-2

SwissProt ID

P12268 (Human), P24547 (Mouse), Q3SWY3 (Bovin)

Gene ID

3615 (IMPDH2)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Ms (Mouse), Rt (Rat), Ze (Zebrafish), African clawed frog, Xen (Xenopus), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Immunoprecipitation (IP)

Background of IMPDH2 antibody

IMPDH2 is the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. It catalyzes the NAD-dependent oxidation of inosine-5\'-monophosphate into xanthine-5\'-monophosphate, which is then converted into guanosine-5\'-monophosphate. IMPDH2 is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5\'-monophosphate into xanthine-5\'-monophosphate, which is then converted into guanosine-5\'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

Fellenberg J, Bernd L, Delling G, Witte D, Zahlten-Hinguranage A.
Prognostic significance of drug-regulated genes in high-grade osteosarcoma.
Mod Pathol. 2007 Oct;20(10):1085-94. Epub 2007 Jul 27.
PMID: 17660802 Comments: Osteosarcoma.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

IMPDH2 antibody

TA305796 (1ug/ml) staining of Human Skeletal Muscle lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

IMPDH2 antibody

Western blot analysis of extracts of various cell lines, using IMPDH2 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

IMPDH2 antibody

WB Suggested Anti-IMPDH2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: 721_B cell lysate. IMPDH2 is supported by BioGPS gene expression data to be expressed in 721_B Rabbit IgG Purified Can, Eq, GP, Hu, Por, Rb, Rt ICC/IF, WB
50 µg / €325.00
  OriGene Technologies, Inc.

IMPDH2 antibody

WB Suggested Anti-IMPDH2 Antibody Titration: 0.2-1 ug/ml; Positive Control: HepG2 cell lysate Rabbit IgG Purified Can, Eq, GP, Hu, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

IMPDH2 antibody

Western blot analysis of IMPDH2 Antibody (Center) (AP17504PU-N) in NCI-H460,Hela,MCF7,A2058 cell line lysates(35ug/lane). IMPDH2 (arrow) was detected using the purified Pab. Rabbit Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

IMPDH2 antibody

IMPDH2 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

IMPDH2 antibody

Western Blot analysis of IMPDH2 expression in transfected 293T cell line (H00003615-T02) by IMPDH2 MaxPab polyclonal antibody.

Lane 1: IMPDH2 transfected lysate(56.54 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

IMPDH2 antibody

Western Blot analysis of IMPDH2 expression in transfected 293T cell line (H00003615-T01) by IMPDH2 MaxPab polyclonal antibody.

Lane 1: IMPDH2 transfected lysate(55.80 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

IMPDH2 antibody

Western Blot analysis of IMPDH2 expression in transfected 293T cell line by IMPDH2 monoclonal antibody (M01), clone 1E12-B6.

Lane 1: IMPDH2 transfected lysate(55.8 KDa).
Lane 2: Non-transfected lysate. Mouse IgG1 1E12-B6 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

IMPDH2 (N-term) antibody

Human Hep-2; . Sample Type :. Human Hep-2 cells. Primary Antibody Dilution :. 1:500. Secondary Antibody :. Goat anti-rabbit-Alexa Fluor 568. Secondary Antibody Dilution :. 1:400. Color/Signal Descriptions :. Red: IMPDH2 Blue: DAPI. Gene Name :. IMPDH2. Submitted by :. S. John Calise, Edward Chan Lab, University of Florida; IMPDH2 antibody - N-terminal region (ARP54365_P050) in Human Hep-2 cells using Immunohistochemistry Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

IMPDH2 antibody

Human HepG2; WB Suggested Anti-IMPDH2 Antibody Titration: 0.2-1 ug/ml. Positive Control: HepG2 cell lysate; IMPDH2 antibody - C-terminal region (ARP54366_P050) in Human HepG2 cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Hu, Ms, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

IMPDH2 antibody

Western Blot: IMPDH2 Antibody [NBP1-28478]-(1ug/ml) staining of Human Skeletal Muscle lysate (35ug protein in RIPA buffer) Goat IgG Aff - Purified Hu E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

IMPDH2 antibody

Western Blot: IMPDH2 Antibody  [NBP1-32093]- (30 µg of whole cell lysate) A:H1299 B:Hep G2 7.5% SDS PAGE diluted at 1:500 Rabbit IgG Hu WB
0.1 ml / €420.00
  Novus Biologicals Inc.

IMPDH2 antibody

Western Blot: IMPDH2 Antibody [NBP1-53028] - This Anti-IMPDH2 antibody was used in Western Blot of HepG2 tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Bov, Can, Chk, Hu, Ms, Rt, Xen, Ze WB
50 µg / €440.00
  Novus Biologicals Inc.

IMPDH2 antibody

Immunohistochemistry-Paraffin: IMPDH2 Antibody [NBP1-86177] - Immunohistochemical staining of human breast shows moderate cytoplasmic and nuclear positivity in glandular cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

IMPDH2

IMPDH2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

IMPDH2 (1-514, His-tag)

IMPDH2 Human Purified > 90 % by SDS - PAGE E. coli
0.25 mg / €940.00
  Acris Antibodies GmbH

IMPDH2 (1-514, His-tag)

IMPDH2 Human Purified > 90 % by SDS - PAGE E. coli
50 µg / €370.00
  Acris Antibodies GmbH

IMPDH2

IMPDH2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

IMPDH2

IMPDH2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

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