IMPDH2 antibody

Principal name

IMPDH2 antibody

Alternative names for IMPDH2 antibody

IMPD2, Inosine-5'-monophosphate dehydrogenase 2, IMP dehydrogenase 2, EC=1.1.1.205, IMPDH-II, IMPD-2

SwissProt ID

P12268 (Human), P24547 (Mouse), Q3SWY3 (Bovin)

Gene ID

3615 (IMPDH2), 23918 (Impdh2)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Ms (Mouse), Rt (Rat), Ze (Zebrafish), African clawed frog, Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of IMPDH2 antibody

IMPDH2 is the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. It catalyzes the NAD-dependent oxidation of inosine-5\'-monophosphate into xanthine-5\'-monophosphate, which is then converted into guanosine-5\'-monophosphate. IMPDH2 is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5\'-monophosphate into xanthine-5\'-monophosphate, which is then converted into guanosine-5\'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

Fellenberg J, Bernd L, Delling G, Witte D, Zahlten-Hinguranage A.
Prognostic significance of drug-regulated genes in high-grade osteosarcoma.
Mod Pathol. 2007 Oct;20(10):1085-94. Epub 2007 Jul 27.
PMID: 17660802 Comments: Osteosarcoma.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

IMPDH2 antibody

  Goat Anti-IMPDH2 Antibody  
TA305796 (1ug/ml) staining of Human Skeletal Muscle lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

IMPDH2 antibody

  Rabbit anti-IMPDH2 Polyclonal Antibody  
Western blot analysis of extracts of various cell lines, using IMPDH2 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

IMPDH2 antibody

  Rabbit Polyclonal Anti-IMPDH2 Antibody  
WB Suggested Anti-IMPDH2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: 721_B cell lysate. IMPDH2 is supported by BioGPS gene expression data to be expressed in 721_B Rabbit IgG Purified Can, Eq, GP, Hu, Por, Rb, Rt ICC/IF, WB
50 µg / €325.00
  OriGene Technologies, Inc.

IMPDH2 antibody

  Rabbit Polyclonal Anti-IMPDH2 Antibody  
WB Suggested Anti-IMPDH2 Antibody Titration: 0.2-1 ug/ml; Positive Control: HepG2 cell lysate Rabbit IgG Purified Can, Eq, GP, Hu, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

IMPDH2 antibody

  Rabbit Polyclonal Anti-IMPDH2 Antibody  
Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane: A549 cells, Primary antibody: (IMPDH2 Antibody) at dilution 1/650, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 minutes Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

IMPDH2 antibody

Western blot analysis of IMPDH2 Antibody (Center) (AP17504PU-N) in NCI-H460,Hela,MCF7,A2058 cell line lysates(35ug/lane). IMPDH2 (arrow) was detected using the purified Pab. Rabbit Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

Impdh2 - mouse gene knockout kit via CRISPR

Impdh2 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Impdh2 - mouse gene knockout kit via CRISPR

Impdh2 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Impdh2 - mouse gene knockout kit via CRISPR

Impdh2 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Impdh2 - mouse gene knockout kit via CRISPR

Impdh2 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

IMPDH2

  Recombinant protein of human IMP (inosine monophosphate) dehydrogenase 2 (IMPDH2)  
IMPDH2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

IMPDH2 (1-514, His-tag)

IMPDH2 Human Purified > 90 % by SDS - PAGE E. coli
0.25 mg / €940.00
  Acris Antibodies GmbH

IMPDH2 (1-514, His-tag)

IMPDH2 Human Purified > 90 % by SDS - PAGE E. coli
50 µg / €370.00
  Acris Antibodies GmbH

Lysates

Catalog No.    

IMPDH2 overexpression lysate

IMPDH2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, IMPDH2 (mGFP-tagged) - Human IMP (inosine 5'-monophosphate) dehydrogenase 2 (IMPDH2), 200 uL, >10^7 TU/mL

Lenti ORF particles, IMPDH2 (mGFP-tagged) - Human IMP (inosine 5'-monophosphate) dehydrogenase 2 (IMPDH2), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, IMPDH2 (Myc-DDK tagged) - Human IMP (inosine 5'-monophosphate) dehydrogenase 2 (IMPDH2) , 200 uL, >10^7 TU/mL

Lenti ORF particles, IMPDH2 (Myc-DDK tagged) - Human IMP (inosine 5'-monophosphate) dehydrogenase 2 (IMPDH2) , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

16 Item(s)

per page
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