Importin 5 / RANBP5 antibody

Principal name

Importin 5 / RANBP5 antibody

Alternative names for Importin 5 / RANBP5 antibody

Importin-5, IPO5, Karyopherin beta-3, KPNB3, Ran-binding protein 5, Importin subunit beta-3

SwissProt ID

O00410 (Human), Q8BKC5 (Mouse)

Gene ID

3843 (IPO5)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), Por (Porcine), Rb (Rabbit)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of Importin 5 / RANBP5 antibody

Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). Mediates the nuclear import of ribosomal proteins RPL23A, RPS7 and RPL5. Binds to a beta-like import receptor binding (BIB) domain of RPL23A. In vitro, mediates nuclear import of H2A, H2B, H3 and H4 histones. In case of HIV-1 infection, binds and mediates the nuclear import of HIV-1 Rev.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Importin 5 / RANBP5 antibody

Western blot analysis of extracts of various cell lines, using IPO5 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

Importin 5 / RANBP5 antibody

WB Suggested Anti-IPO5 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: Jurkat cell lysate. IPO5 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells Rabbit IgG Purified Bov, Can, Eq, Hu, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

Importin 5 / RANBP5 antibody

Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE) Mouse IgG1 1C4 Purified Hu E, P, WB
50 µg / €530.00
  Acris Antibodies GmbH

Importin 5 / RANBP5 (N-term) antibody

Importin 5 / RANBP5 Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

Importin 5 / RANBP5 (importin) antibody

Importin 5 / RANBP5 Rabbit Aff - Purified Hu WB
50 µg / €440.00
  Novus Biologicals Inc.

5 Item(s)

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