ING3 antibody

Principal name

ING3 antibody

Alternative names for ING3 antibody

HSPC301, Inhibitor of growth protein 3, p47ING3

SwissProt ID

Q498T3 (Rat), Q5ZK36 (Chick), Q7ZX31 (Xenla), Q8VEK6 (Mouse), Q9HC99 (Human), Q9NXR8 (Human)

Gene ID

54556 (ING3), 312154 (Ing3)

Available reactivities

Hu (Human), Rt (Rat), Chk (Chicken), Ms (Mouse), Chimp (Chimpanzee), Bov (Bovine), Can (Canine), Ze (Zebrafish), African clawed frog, Mky (Monkey), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit), Ye (Yeast)

Available hosts

Mouse, Goat, Rabbit

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of ING3 antibody

ING3 is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers.The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers. Two alternatively spliced transcript variants encoding different isoforms have been observed.

General readings

Gunduz,M., (2008) Cancer Sci. 99 (3), 531-538

16 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ING3 antibody

  Goat polyclonal anti-p47 ING3 antibody  
WB using anti-ING3 antibody shows detection of a band at ~55 kDa corresponding to ING3 in RKO cells transfected with ING3 (lane 2). Control RKO cells do not show detection of this specific band (lane 1). The identity of the non-specific bands at 33 kDa and 20 kDa has not been determined. Primary antibody was used at 1:1,000. Secondry antibody was a 1:20,000 dilution of IRDye™800 conjugated Rb-a-Goat IgG [H&L]. Goat Aff - Purified Can, Chk, Hu, Mky, Ms, Rt E
0.1 mg / €356.00
  OriGene Technologies, Inc.

ING3 antibody

  Rabbit anti-ING3 Polyclonal Antibody  
Western blot analysis of extracts of various cell lines, using ING3 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

ING3 antibody

  Rabbit Polyclonal Anti-ING3 Antibody  
WB Suggested Anti-ING3 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: HepG2 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

ING3 antibody

  Rabbit Polyclonal Anti-ING3 Antibody  
WB Suggested Anti-ING3 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: Human heart Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ye, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

ING3 antibody

AP07597PU-N ING3 antiboy staining of Formalin-Fixed Paraffin-Embedded Human Brain, Cortex at 2.5 µg/ml followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Goat Aff - Purified Hu E, ICC/IF, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

ING3 Control Peptide

ING3 Purified
50 µg / €200.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

ING3 - human gene knockout kit via CRISPR

ING3 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

ING3 - human gene knockout kit via CRISPR

ING3 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

ING3 - human gene knockout kit via CRISPR

ING3 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

ING3 - human gene knockout kit via CRISPR

ING3 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

ING3 (transcript variant 1)

  Recombinant protein of human inhibitor of growth family, member 3 (ING3), transcript variant 1  
ING3 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Lysates

Catalog No.    

ING3 overexpression lysate

ING3 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, ING3 (mGFP-tagged)-Human inhibitor of growth family, member 3 (ING3), transcript variant 3, 200 uL, >10^7 TU/mL

Lenti ORF particles, ING3 (mGFP-tagged)-Human inhibitor of growth family, member 3 (ING3), transcript variant 3, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, ING3 (Myc-DDK-tagged)-Human inhibitor of growth family, member 3 (ING3), transcript variant 3, 200 uL, >10^7 TU/mL

Lenti ORF particles, ING3 (Myc-DDK-tagged)-Human inhibitor of growth family, member 3 (ING3), transcript variant 3, 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Ing3 (GFP-tagged ORF) - Rat inhibitor of growth family, member 3 (Ing3), 200 uL, >10^7 TU/mL

Lenti ORF particles, Ing3 (GFP-tagged ORF) - Rat inhibitor of growth family, member 3 (Ing3), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Ing3 (Myc-DDK-tagged ORF) - Rat inhibitor of growth family, member 3 (Ing3), 200 uL, >10^7 TU/mL

Lenti ORF particles, Ing3 (Myc-DDK-tagged ORF) - Rat inhibitor of growth family, member 3 (Ing3), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

16 Item(s)

per page
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