Inositol monophosphatase / IMPA1 antibody

Principal name

Inositol monophosphatase / IMPA1 antibody

Alternative names for Inositol monophosphatase / IMPA1 antibody

IMPA, IMPase 1, Inositol-1(or 4)-monophosphatase, Lithium-sensitive myo-inositol monophosphatase A1

SwissProt ID

O55023 (Mouse), O77591 (Pig), P20456 (Bovin), P29218 (Human), P29219 (Xenla), P97697 (Rat)

Gene ID

3612 (IMPA1), 3612296 (IPR001365)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Por (Porcine), African clawed frog, GP (Guinea Pig), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of Inositol monophosphatase / IMPA1 antibody

This gene encodes an enyzme that dephosphorylates myo-inositol monophosphate to generate free myo-inositol, a precursor of phosphatidylinositol, and is therefore an important modulator of intracellular signal transduction via the production of the second messengers myoinositol 1,4,5-trisphosphate and diacylglycerol. This enzyme can also use myo-inositol-1,3-diphosphate, myo-inositol-1,4-diphosphate, scyllo-inositol-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates. This enzyme shows magnesium-dependent phosphatase activity and is inhibited by therapeutic concentrations of lithium. Inhibition of inositol monophosphate hydroylosis and subsequent depletion of inositol for phosphatidylinositol synthesis may explain the anti-manic and anti-depressive effects of lithium administered to treat bipolar disorder. Alternative splicing results in multiple transcript variants encoding distinct isoforms. A pseudogene of this gene is also present on chromosome 8q21.13. [provided by RefSeq]

General readings

Schapiro MB., et al. (2002) Neurobiol Aging. 23(3):389-96.

18 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Inositol monophosphatase / IMPA1 antibody

WB Suggested Anti-IMPA1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:1562500; Positive Control: Human heart Rabbit IgG Purified Bov, Can, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

Inositol monophosphatase / IMPA1 antibody

Inositol monophosphatase / IMPA1 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

Inositol monophosphatase / IMPA1 antibody

Western Blot analysis of IMPA1 expression in transfected 293T cell line (H00003612-T01) by IMPA1 MaxPab polyclonal antibody.

Lane 1: IMPA1 transfected lysate(30.47 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

Inositol monophosphatase / IMPA1 antibody

Western Blot analysis of IMPA1 expression in transfected 293T cell line (H00003612-T01) by IMPA1 MaxPab polyclonal antibody.

Lane 1: IMPA1 transfected lysate(30.20 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu, Ms E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

Inositol monophosphatase / IMPA1 antibody

Inositol monophosphatase / IMPA1 Mouse IgG1 1E6-F11 Purified Hu E, WB
50 µg / €370.00
  Abnova Taiwan Corp.

Inositol monophosphatase / IMPA1 antibody

Inositol monophosphatase / IMPA1 Mouse IgG1 1E6-F11 Ascites Hu E, WB
0.2 ml / €370.00
  Abnova Taiwan Corp.

Inositol monophosphatase / IMPA1 antibody

Human Heart; WB Suggested Anti-IMPA1 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: Human heart; IMPA1 antibody - middle region (ARP58713_P050) in Human Heart cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Hu, Ms, Por, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

Inositol monophosphatase / IMPA1 antibody

Immunohistochemistry-Paraffin: IMPA1 Antibody [NBP1-83107] - Immunohistochemical staining of human testis shows strong cytoplasmic and nuclear positivity in seminiferous tubules. Rabbit IgG Aff - Purified Hu ICC/IF, P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Inositol monophosphatase / IMPA1 (transcript variant 1)

Inositol monophosphatase / IMPA1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Inositol monophosphatase / IMPA1 (transcript variant 2)

Inositol monophosphatase / IMPA1 Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
10 µg / €399.00
  OriGene Technologies, Inc.

Inositol monophosphatase / IMPA1 (1-277, His-tag)

Inositol monophosphatase / IMPA1 Human Purified > 95 % E. coli
0.5 mg / €750.00
  Acris Antibodies GmbH

Inositol monophosphatase / IMPA1 (1-277, His-tag)

Inositol monophosphatase / IMPA1 Human Purified > 95 % E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

Inositol monophosphatase / IMPA1

Inositol monophosphatase / IMPA1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

Inositol monophosphatase / IMPA1

Inositol monophosphatase / IMPA1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Inositol monophosphatase / IMPA1

Inositol monophosphatase / IMPA1 Human Purified
0.1 mg / €380.00
  Novus Biologicals Inc.

Inositol monophosphatase / IMPA1

Inositol monophosphatase / IMPA1 Human Purified
0.5 mg / €870.00
  Novus Biologicals Inc.

Lysates

Catalog No.    

IMPA1 293T Cell Transient Overexpression Lysate(Denatured)

IMPA1 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

IMPA1 overexpression lysate

IMPA1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

18 Item(s)

per page
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