INPP5B / 5PTase 2 antibody

Principal name

INPP5B / 5PTase 2 antibody

Alternative names for INPP5B / 5PTase 2 antibody

Type II inositol-1,4,5-trisphosphate 5-phosphatase, Phosphoinositide 5-phosphatase, 75 kDa inositol polyphosphate-5-phosphatase

SwissProt ID

P32019 (Human)

Gene ID

3633 (INPP5B)

Available reactivities

Hu (Human), Can (Canine), Ms (Mouse), Rt (Rat), Eq (Equine), GP (Guinea Pig), Por (Porcine)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Flow Cytometry (F), Paraffin Sections (P)

Background of INPP5B / 5PTase 2 antibody

Cellular calcium sigling is controlled by the production of inositol phosphates (IPs) by phospholipase C in response to extracellular sigls. The IP sigling molecules are ictivated by a family of inositol polyphosphate-5-phosphatases (5-phosphatases). INPP5B is the type II 5-phosphatase. The protein is localized to the cytosol and mitochondria, and associates with membranes through an isoprenyl modification near the C-terminus.Cellular calcium sigling is controlled by the production of inositol phosphates (IPs) by phospholipase C in response to extracellular sigls. The IP sigling molecules are ictivated by a family of inositol polyphosphate-5-phosphatases (5-phosphatases). This gene encodes the type II 5-phosphatase. The protein is localized to the cytosol and mitochondria, and associates with membranes through an isoprenyl modification near the C-terminus. Several altertively spliced transcript variants of this gene have been described, but the full-length ture of some of these variants has not been determined.

General readings

Coon, B.G., et al. Hum. Mol. Genet. 18(23):4478-4491(2009)
Mao, Y., et al. EMBO J. 28(13):1831-1842(2009)
Williams, C., et al. J. Cell. Sci. 120 (PT 22), 3941-3951 (2007)
Speed, C.J., et al. Eur. J. Biochem. 234(1):216-224(1995)
Janne, P.A., et al. Genomics 28(2):280-285(1995)

13 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

INPP5B / 5PTase 2 antibody

Sample (30 ug of whole cell lysate). A: H1299. 7.5% SDS PAGE. TA308024 diluted at 1:1000. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

INPP5B / 5PTase 2 antibody

WB Suggested Anti-INPP5B Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: Hela cell lysate Rabbit IgG Purified Can, Eq, GP, Hu, Ms, Por, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

INPP5B / 5PTase 2 (C-term) antibody

Immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle reacted with INPP5B / 5PTase 2 Antibody (C-term) Cat.-No AP52214PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining. Rabbit Ig Aff - Purified Hu F, P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

INPP5B / 5PTase 2 antibody

Western Blot analysis of INPP5B expression in transfected 293T cell line (H00003633-T01) by INPP5B MaxPab polyclonal antibody.

Lane 1: INPP5B transfected lysate(82.28 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

INPP5B / 5PTase 2 antibody

INPP5B / 5PTase 2 Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

INPP5B / 5PTase 2 antibody

Human HeLa; WB Suggested Anti-INPP5B Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: Hela cell lysate; INPP5B antibody - middle region (ARP54772_P050) in Human HeLa cells using Western Blot Rabbit Aff - Purified Can, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

CRISPR

Catalog No. Species Donor Vector  

INPP5B - human gene knockout kit via CRISPR

INPP5B - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

INPP5B - human gene knockout kit via CRISPR

INPP5B - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

INPP5B - human gene knockout kit via CRISPR

INPP5B - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

INPP5B - human gene knockout kit via CRISPR

INPP5B - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

INPP5B / 5PTase 2

INPP5B / 5PTase 2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

INPP5B / 5PTase 2

INPP5B / 5PTase 2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

INPP5B 293T Cell Transient Overexpression Lysate(Denatured)

INPP5B 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

13 Item(s)

per page
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