INPPL1 antibody

Principal name

INPPL1 antibody

Alternative names for INPPL1 antibody

INPPL-1, SHIP2, SHIP-2, Inositol polyphosphate phosphatase-like protein 1, Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2, SH2 domain-containing inositol-5'-phosphatase 2

SwissProt ID

O15357 (Human), Q6P549 (Mouse), Q9WVR3 (Rat)

Gene ID

3636 (INPPL1), 16332 (Inppl1)

Available reactivities

Hu (Human), Rt (Rat), Ms (Mouse)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Flow Cytometry (F), Paraffin Sections (P)

Background of INPPL1 antibody

INPPL1 (Inositol polyphosphate phosphatase-like 1), also called SHIP2, encodes inositol polyphosphate-5 phosphatase-like 1, a protein that in addition to the phosphatase domain contains an SH2 (src-homology domain 2) motif. INPPL1 is a member of the family of inositol triphosphate phosphatases. The INPPL1 gene is mapped on 11q13.4. Immunoblot analysis revealed that SHIP2 was widely expressed in fibroblast and nonhematopoietic tumor cell lines, unlike the SHIP protein, which was found only in cell lines of hematopoietic origin. Using human epithelial cell lines and primary human corneal and epidermal keratinocytes, Yu et al. (2008) showed that microRNA-184 (MIR184) interfered with the ability of MIR205 to downregulate expression of SHIP2.SHIP2 may play a significant role in regulation of phosphatidylinositol 3-prime-kinase signaling by growth factors and insulin. By targeting the translation-initiating ATG codon and deleting the first 18 exons encoding Inppl1, Sleeman et al. (2005) generated Inppl1 -/- mice that were null for Inppl1 mRNA and protein.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

INPPL1 antibody

Confocal immunofluorescent analysis of HeLa cells labeled with SHIP2 Antibody (left, green) compared to a nonspecific negative control antibody (right). Actin filaments have been labeled with Alexa Fluor® 555 phalloidin (red). Blue pseudocolor = DRAQ5™ (fluorescent DNA dye).  Rabbit Aff - Purified Hu, Rt F, ICC/IF, IP, WB
0.1 ml / €410.00
  Neuromics Antibodies

CRISPR

Catalog No. Species Donor Vector  

INPPL1 - human gene knockout kit via CRISPR

INPPL1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

INPPL1 - human gene knockout kit via CRISPR

INPPL1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

INPPL1 - human gene knockout kit via CRISPR

INPPL1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

INPPL1 - human gene knockout kit via CRISPR

INPPL1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

INPPL1 overexpression lysate

INPPL1 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

Lysates (Knockout)

Catalog No.    

INPPL1-knockout Cell lysate

INPPL1-knockout Cell lysate  
0.1 mg / €495.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, INPPL1 (mGFP-tagged)-Human inositol polyphosphate phosphatase-like 1 (INPPL1), 200 uL, >10^7 TU/mL

Lenti ORF particles, INPPL1 (mGFP-tagged)-Human inositol polyphosphate phosphatase-like 1 (INPPL1), 200 uL, >10^7 TU/mL  
200 µl / €1,320.00
  OriGene Technologies, Inc.

Lenti ORF particles, INPPL1 (Myc-DDK-tagged)-Human inositol polyphosphate phosphatase-like 1 (INPPL1), 200 uL, >10^7 TU/mL

Lenti ORF particles, INPPL1 (Myc-DDK-tagged)-Human inositol polyphosphate phosphatase-like 1 (INPPL1), 200 uL, >10^7 TU/mL  
200 µl / €1,180.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Inppl1 (GFP-tagged) - Mouse inositol polyphosphate phosphatase-like 1 (Inppl1), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, Inppl1 (GFP-tagged) - Mouse inositol polyphosphate phosphatase-like 1 (Inppl1), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €2,120.00
  OriGene Technologies, Inc.

Lenti ORF particles, Inppl1 (GFP-tagged) - Mouse inositol polyphosphate phosphatase-like 1 (Inppl1), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, Inppl1 (GFP-tagged) - Mouse inositol polyphosphate phosphatase-like 1 (Inppl1), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €2,120.00
  OriGene Technologies, Inc.

Lenti ORF particles, Inppl1 (Myc-DDK-tagged) - Mouse inositol polyphosphate phosphatase-like 1 (Inppl1), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, Inppl1 (Myc-DDK-tagged) - Mouse inositol polyphosphate phosphatase-like 1 (Inppl1), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,910.00
  OriGene Technologies, Inc.

Lenti ORF particles, Inppl1 (Myc-DDK-tagged) - Mouse inositol polyphosphate phosphatase-like 1 (Inppl1), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, Inppl1 (Myc-DDK-tagged) - Mouse inositol polyphosphate phosphatase-like 1 (Inppl1), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,910.00
  OriGene Technologies, Inc.

13 Item(s)

per page
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